794 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS active agents. It has been found to be particularly useful for glycol esters and sorbitan esters. Some of the possibilities of extension of this work to quantitative analysis of the components of these surface-active agents has been mentioned. In addition, fatty amides and ethanola- mines have been indicated as areas of research that would merit further interest. (Received July 16, 1965) (i) (2) (3) (4) (5) (6) (7) (8) (9) (10) (11) (12) (13) (14) (15) (16) REFERENCES Hofmann, A. F., J. Lipid Res., 3,391 (1962). Hamilton, J. G. and Holman, T. T., J. Am. Chem. Soc., 76, 4107 (1954). Huebner, V. R., J. Am. Chem. Soc., 35,325 (1958). Holasek, A., and Fried, J., Mikrochim Acta, 1957, 469. Dieckert, J. W., and Reiser, R., J. Am. Oil Chem. Soc., 33, 123 (1956). Privett, O. S., and Blank, M. L., Ibid., 39,520 (1962). Rybecka, S. M., Chem. Ind. (London) 1962, 308. Vioque, E., and Holman, R. T., J. Am. Oil Chem. Soc., 39, 63 (1962). Perry, E. S., and Brokow, G. Y., Ibid., 32,652 (1955). Monick, J. A., and Treybal, R. E., Ibid., 3/!, 193 (1956). Fryer, F. H., Ormand, W. L., and Crump, G. B., Ibid., 37,589 (1960). McInnes, A. G., Tattrie, N.H., and Kater, M., Ibid., 37, 7 (1960). Huebner, V. R., Ibid., 36,262 (1959). Sweeley, C. C., Bentley, R., Makita, M., and Wells, W. W., J. Am. Chem. Soc., 85, 2497 (1903). Bentley, R., Sweeley, C. C., Makita, M., and Wells, W. W., Biochem. Biophys. Research Commun., 11, 14 (1963). Wood, R. D., Raju, P. K., and Reiser, R., J. Am. Chem. Soc., 42, 161 (1965). ERRATUM Due to language difficulties an unavoidable error occurred in the synopsis of "Approaches to a Prophylaxis of Skin Aging," by M. and H. Ippen, J. Soc. Cosmetic Chemists, 16, 305-8 (1965). The corrected synopsis should read as follows: Synopsis--It is shown that smoking has a deleterious effect on skin condition and that this effect can be differentiated from that of damage by sunlight. Smoker's skin is identified as skin which suffers from loss of "turgor" and shows signs of flabbincss in addition, the color of the smoker's skin is pale, with a grayish hue. Dermatological examination of 224 women up to now show moderate correlation between their smoking habits and the appear- ance of their skin, as defined above. By contrast, smoking seems to have only a very minor effect on the skin of male smokers. For the convenience of the readers, the corrected synopsis is repeated on page xxxvii for use in card indexes.
Book Reviews •.}BER DIE WIRKUNGSWEISE INDIF- FERENTER SALBEN UND EMULSIONS- SYSTEME AN DER HAUT IN ABItJiNGIG- KmT VON •HRER ZUSAMM•NS•TZUNO (Action of Plain Ointments and Emul- sion Systems on Skin as a Function of Their Composition), edited by H. Tronnier. Editio Cantor Kg., Aulen- dorf, 1964. 178 pages, indexed. Price 25 DM, paper bound. This booklet is Volume V of the Berufsdermatosen monographs. In it Tronnier describes the performance of 36 different ointment and lotion bases and discusses their effect on normal or healthy skin. Tronnier uses eleven tests to evaluate these formulations: adhesion to the skin transfer from the skin effect of bases on the dyeing and washability of the skin immersion test penetration through the bases (from the outside to the skin and from inside to the surrounding) effect of temperature of the skin melting of the bases at skin temperature gloss on the skin friction on the skin change of reso- nance frequency of the skin (moistur- izing action) and effect of the bases on alkali-neutralization by the skin. The cosmetic chemist and derma- tologist will find much of interest in 795 this booklet. Although one need not necessarily agree with all of Tron- nier's conclusions nor approve his test procedures, the ideas are provocative and merit careful review. It is evi- dent that the discussion of plain bases is only part of the problem since the bases do not include the "active" component of the cosmetic or derma- tological formulation. Once the "actives" are included in the base, questions of drug transfer, penetra- tion, and inactivation become impor- tant. Nevertheless, a few of the comments by Tronnier are particu- larly noteworthy. He observed little or no influence by the pH of the bases, whether they be o/w or w/o emul- sions. The addition of silicones, in the hands of Tronnier, has failed to increase the barrier properties of petrolatum or of standard o/w emul- sions. In summary, this volume describes a considerable amount of original experimental work. The experi- mental data and the background are supported by numerous (over 300) references to the original literature. As a result, this booklet is worthwhile reading for all cosmetic chemists.-- M. M. RmG•R--Warner-Lambert Research Institute.
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794 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS active agents. It has been found to be particularly useful for glycol esters and sorbitan esters. Some of the possibilities of extension of this work to quantitative analysis of the components of these surface-active agents has been mentioned. In addition, fatty amides and ethanola- mines have been indicated as areas of research that would merit further interest. (Received July 16, 1965) (i) (2) (3) (4) (5) (6) (7) (8) (9) (10) (11) (12) (13) (14) (15) (16) REFERENCES Hofmann, A. F., J. Lipid Res., 3,391 (1962). Hamilton, J. G. and Holman, T. T., J. Am. Chem. Soc., 76, 4107 (1954). Huebner, V. R., J. Am. Chem. Soc., 35,325 (1958). Holasek, A., and Fried, J., Mikrochim Acta, 1957, 469. Dieckert, J. W., and Reiser, R., J. Am. Oil Chem. Soc., 33, 123 (1956). Privett, O. S., and Blank, M. L., Ibid., 39,520 (1962). Rybecka, S. M., Chem. Ind. (London) 1962, 308. Vioque, E., and Holman, R. T., J. Am. Oil Chem. Soc., 39, 63 (1962). Perry, E. S., and Brokow, G. Y., Ibid., 32,652 (1955). Monick, J. A., and Treybal, R. E., Ibid., 3/!, 193 (1956). Fryer, F. H., Ormand, W. L., and Crump, G. B., Ibid., 37,589 (1960). McInnes, A. G., Tattrie, N.H., and Kater, M., Ibid., 37, 7 (1960). Huebner, V. R., Ibid., 36,262 (1959). Sweeley, C. C., Bentley, R., Makita, M., and Wells, W. W., J. Am. Chem. Soc., 85, 2497 (1903). Bentley, R., Sweeley, C. C., Makita, M., and Wells, W. W., Biochem. Biophys. Research Commun., 11, 14 (1963). Wood, R. D., Raju, P. K., and Reiser, R., J. Am. Chem. Soc., 42, 161 (1965). ERRATUM Due to language difficulties an unavoidable error occurred in the synopsis of "Approaches to a Prophylaxis of Skin Aging," by M. and H. Ippen, J. Soc. Cosmetic Chemists, 16, 305-8 (1965). The corrected synopsis should read as follows: Synopsis--It is shown that smoking has a deleterious effect on skin condition and that this effect can be differentiated from that of damage by sunlight. Smoker's skin is identified as skin which suffers from loss of "turgor" and shows signs of flabbincss in addition, the color of the smoker's skin is pale, with a grayish hue. Dermatological examination of 224 women up to now show moderate correlation between their smoking habits and the appear- ance of their skin, as defined above. By contrast, smoking seems to have only a very minor effect on the skin of male smokers. For the convenience of the readers, the corrected synopsis is repeated on page xxxvii for use in card indexes.
Book Reviews •.}BER DIE WIRKUNGSWEISE INDIF- FERENTER SALBEN UND EMULSIONS- SYSTEME AN DER HAUT IN ABItJiNGIG- KmT VON •HRER ZUSAMM•NS•TZUNO (Action of Plain Ointments and Emul- sion Systems on Skin as a Function of Their Composition), edited by H. Tronnier. Editio Cantor Kg., Aulen- dorf, 1964. 178 pages, indexed. Price 25 DM, paper bound. This booklet is Volume V of the Berufsdermatosen monographs. In it Tronnier describes the performance of 36 different ointment and lotion bases and discusses their effect on normal or healthy skin. Tronnier uses eleven tests to evaluate these formulations: adhesion to the skin transfer from the skin effect of bases on the dyeing and washability of the skin immersion test penetration through the bases (from the outside to the skin and from inside to the surrounding) effect of temperature of the skin melting of the bases at skin temperature gloss on the skin friction on the skin change of reso- nance frequency of the skin (moistur- izing action) and effect of the bases on alkali-neutralization by the skin. The cosmetic chemist and derma- tologist will find much of interest in 795 this booklet. Although one need not necessarily agree with all of Tron- nier's conclusions nor approve his test procedures, the ideas are provocative and merit careful review. It is evi- dent that the discussion of plain bases is only part of the problem since the bases do not include the "active" component of the cosmetic or derma- tological formulation. Once the "actives" are included in the base, questions of drug transfer, penetra- tion, and inactivation become impor- tant. Nevertheless, a few of the comments by Tronnier are particu- larly noteworthy. He observed little or no influence by the pH of the bases, whether they be o/w or w/o emul- sions. The addition of silicones, in the hands of Tronnier, has failed to increase the barrier properties of petrolatum or of standard o/w emul- sions. In summary, this volume describes a considerable amount of original experimental work. The experi- mental data and the background are supported by numerous (over 300) references to the original literature. As a result, this booklet is worthwhile reading for all cosmetic chemists.-- M. M. RmG•R--Warner-Lambert Research Institute.

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