THE SEBACEOUS GLANDS 411 (7) (8) (9) (10) REFERENCES (1) Montagna, W. in Montagna, W., Ellis, R. A. and Silver, A. F. Advances in biology o] skin 4 19 (1963) (Pergamon Press, Oxford). (2) Strauss, J. S. and Pochi, P. E. J. Invest. Dermatol. 36 293 (1961). (3) Strauss, J. S. and Pochi, P. E. Recent Progr. Hormone Res. 19 385 (1963). (4) Strauss, J. S. and Pochi, P. E. in Montagna, W., Ellis, R. A. and Silver, A. F. Advances in biology of skin 4 220 (1963) (Pergamon Press, Oxford). (5) Miles, A. E. in Montagna, W., Ellis, R. A. and Silver, A. F. Advances in biology of skin 4 46 (1963) (Pergamon Press, Oxford). (6) Montagna, W. in Montagna, W., Ellis, R. A. and Silver, A. F. Advances in biology of skin 4 32 (1963) (Pergamon Press, Oxford). Quay, W. B. Anat. Record. 119 161 (1954). Martan, J., J. Morphol. 110 285 (1962). Green, L. M. A. Australian J. Zool. 11 250 (1963). Serri, F. and Huber, W. M. in Montagna, W., Ellis, R. A. and Silver, A. F. Advances in biology of skin 4 1 (1963) (Pergamon Press, Oxford). (11) Nicolaides, N. in Montagna, W., Ellis, R. A. and Silver, A. F. Advances in biology of skin 4 167 (1963) (Pergamon Press, Oxford). (12) Wheatley, V. R. in Montagna, W., Ellis, R. A. and Silver, A. F. Advances in biologyof skin 4 135 (1963) (Pergamon Press, Oxford). (13) Yeares, N. T. M. Australian J. Agri. Res. 6 891 (1955). (14) Blank, I. H. J. Invest. Dermatol. 18 433 (1952). (15) Blank, I. H. J. Invest. Dermatol. 21 259 (1953). (16) Rothman, S. Physiology and biochemistry of the skin, Chapter 13 (1954) (University Press, Chicago). (17) Kligman, A.M. in Montagna, W., Ellis, R. A. and Silver, A. F. Advances in biology of skin 4 110 (1963) (Pergamon Press, Oxford). (18) Jarrett, A. Brit. J. Dermatol. 76 295 (1964). (19) Ebling, F. J. J. Endocrinol. 5 297 (1948). (20) Montagna, W. and Kenyon, P. Anat. Record 103 365 (1949). (21) Hamilton, J. B. and Montagna, W. Am. J. Anat. 86 191 (1950). (22) Lapi•re, C. C.R. Soc. Biol. Paris 147 1302 (1953). (23) Strauss, J. S., Kligman, A.M. and Pochi, P. E. J. Invest. Dermatol. 39 139 (1962). (24) Pochi, P. E., Strauss, J. S. and Mescon, H. J. Invest. Dermatol. :39 475 (1962). (25) Lasher, iW., Lorincz, A. L. and Rothman, S. J. Invest. Dermatol. 24 499 (1955). (26) Ebling, F. J. J. Endocrinol. 15 297 (1957). (27) Lorincz, A. L. and Lancaster, G. Science 126 124 (1957). (28) Pochi, P. E. and Strauss, J. S. Arch. Dermatol. 88 729 (1963). (29) Ebling, F. J. J. Endocrinol. ? 288 (1951). (30) Ebling, F. J. J. Endocrinol. 10 147 (1954). (31) Jarrett, A. Brit. J. Dermatol. 67 165 (1955). (32) Ebling, F. J. J. Embryol. Exp. Morphol. 5 74 (1957). (33) Ebling, F. J. J. Endocrinol. 12 38 (1955). (34) Hodgson-Jones, I. S., Mackenna, R. M. B. and Wheatley, V. R. Acta Dermato-Venereol. 32 (Suppl. 29) 151 (1952). (35) Strauss, J. S. and Kligman, A.M. J. Invest. Dermatol. 36 309 (1961). (36) Smith, J. G. Arch. Dermatol. Syph. Chicago 80 663 (1959). (37) Jarrett, A. Brit. J. Dermatol. 71 102 (1959). (38) Haskin, D., Lasher, N. and Rothman, S. J. Invest. Dermatol. 20 207 (1953). (39) Ebling, F. J. Brit. J. Dermatol. 73 65 (1961). (40) Ebling, F. J. in Montagna, W., Ellis, R. A. and Silver, A. F. Advances in biology of skin 4 200 (1963) (Pergamon Press, Oxford).

Book reviews THE HALOGENATED HYDROCARBONS OF INDUSTRIAL AND TOXICOLOGICAL IMPORTANCE. W. F. Von Oettingen. Pp. x -• 300 h- Ill. (1964.) Elsevier Publishing Company/Amsterdam/ London/New York. 60s. Those who have had occasions to consult the literature on the toxicology of the halogenated hydrocarbons will certainly be familiar with the name of the author, Dr. Von Oettingen, who has compiled this volume. To cosmetic chemists, the subject is primarily of interest in connection with the use of aerosol propellants and they will find here a comprehensive review of relevant material, even though it does not deal specifically with all the propellants in current use. The book is quite small and easy to follow, provided that the reader has some knowledge of physiology. The compounds with which it deals are divided into methane, ethane, ethylene and Butadiene derivatives, each chapter being subdivided for individual compounds such as methylene chloride and vinyl chloride, for example. Each of these selected com- pounds has a concise monograph, outlining its chemigtry, manufacture, uses, detection and determination, absorption rate and excretion, determi- nation in biological materials, toxicity for animals and man, prognosis, treatment and prevention of toxic effects. The paragraphs dealing with toxic effects are written mainly as reviews of the literature and are well referenced. There is a subject index, simply and adequately arranged for ease of consulting the main items in the book. The cosmetic chemist is quite likely to encounter situations demanding a decision on whether a particular compound is safe for a special application and he cannot expect to find a ready-made answer in this or any other work of reference. He will still have to estimate or determine the acute and chronic exposure in the actual conditions of use and then utilize information such as Dr. Von Oettingen provides, in order to evaluate the hazards. For such purposes, this is an excellent contribution and it will be useful as a guide to the toxic hazards that might arise in manufacturing and packaging areas, as well as in relation to the final consumer. N.J. VAN ABBE. 413