SKIN PENETRATION 633 (82) (8•) (84) (8•) (87) (88) (89) 0o) (9•) 02) 06) (97) (98) (9.•) (loo) (lOl) 002) 003) 004) 005) Aguiar, A. J., and Weiner, M. H., Percutaneous absorption studies of chloramphenicol solutions, Ibid., 58, 210 (1969). Rothman, S., Physiology and Biochemistry of the Skin, University of Chicago Press, Chicago, 1954. Barr, M. J., Percutaneous absorption, J. Pharm. Sci., 51, 395 (1962). Munro, D. D., The relationship between percutaneous absorption and stratum corneum retention, Brit. ]. Dermatol., 81, Suppl. 4, 92 (1969). Sarkany, I., and Hadgraft, J. W., The influence of formulation on topical cortico- steroid activity, Ibid., 81, Suppl. 4, 98 0969). Poulsen, B., The use of models in estimating vehicle effects on the activity of topical corticosteroid formulations, Ibid., 82, Suppl. 6, 49 0970). Sarkany, I., Hadgraft, J. w., caron, G. A., and Barrett, C. W., The role of vehicles in the percutaneous absorption of corticosteroids, Ibid., 77, 569 0965). Garb, J., Ncvus verrucosus unilateris cured with podophyllin ointment, Arch. Dermatol., 81, 606 (1960). Schultz, J. R., Topical therapy of psoriasis with fluocinolone acetonide, Ibid., 84, 1029 (1961). Allenby, A. C., Creasy, N.H., Edgington, A. G., Fletcher, J. A., and Schock, C., Mecha- nism of action of accelerants on skin penetration, Brit. J. Dermatol., 81, Suppl. 4, 47 (1969). Elfbaum, S. G., and Laden, K., The effect of dimethyl sulfoxide on percutaneous ab- sorption: A mechanistic study, Part I, J. Soc. Cosmet. Chem., 19, 119 (1968). Elfbaum, S. G., and Laden, K., The effect of dimethyl sulfoxide on percutaneous ab- sorption: A mechanistic study, Part III, Ibid., 19, 841 (1968). MacKee, G. M., Su]zberger, M. B., Herrmann, F., and Baer, R. L., Histological studies on percutaneous penetration with special reference to the effect of vehicles, J. Invest. Dermalol., 6, 4• (1945). Feldmann, R. J., and Maibach, H. I., Percutaneous penetration of •C hydrocortisone in man. II. Effect of certain bases and pretreatments, Arch. Dermatol., 94, 649 (1966). Portnoy, B., The effect ooe formulation on the clinical response to topical fiuocinolone acetonide, Brit. J. Dermatol., 77, •79 (196•). Cahlwell, I. W., Hall-Smith, S. P., Main, R. A., Ashurst, P. J., Kurton, V., Simpson, W. T., and Williams, G. W., Clinical e•aluation of a new topical corticosteroid be- c]omethasone dipropionate, Ibid., 81), 11 (1968). Tis•,ot, J., and Osmundsen, P. E., Influence of vehicles on the topical activity of fiuoro- methalone, Acta Dermato-Venereol., 46, 447 (1966). Brode, E., Die percutane resorption yon corticosteroiden. II. Die resorption yon fiuo- cinolonacetonid dutch normale rattenhaut und ihre beeinfiussung, Arzneim.-Forsch., 18, 580 (1968). Dillaha, C. J., Jansen, G. T., and Honeycutt, M. •V., Quart. Bull. Dermatol. Found., New York, 1966. Stoughlon, R. B., Percutaneous absorption, Toxicoh Appl. Pharmacol., 7, 1 (1965). Suhberger, M. B., Cortese, T. A., Fishman, L., Wiley, H. S., and Peyakowisch, P.S., Some effects of DMSO on human skin in vivo, Ann. N.Y. Acad. Sci., 141,437 (1967). Jacob, 8. W., and Wood, D.C., Dimethylsulfoxide: Toxicology, pharmacology and current clinical usefulness, Arzneim.-Forsch., 17, 553 (1967). Perman, F., and Wolfe, H. F., Dimethyl sulfoxide as a penetrant carrier of allergens through intact hmnan skin, J. Allergy, 38, 299 (1966). Reiss, F., Percutaneous absorption, a critical and historical review, Amer. J. Med. Sci., 252, 588 (1966).

634 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS (106) (107) (108) (109) (110) (111) (112) ,,(113) (114) (115) (116) (117) (118) (119) (120) Maibach, H. I., and Feldmann, R. J., The effect .of DMSO on percutaneous penetration of hydrocortisone and testosterone in man, Ann. N.Y. Acad. Sci., 141, 425 (1967). Ritschel, W. A., Sorption promoters in biopharmaceutics, Angew. Chem., Int. Ed., 8, 699 (1969). Baker, H. J., The effects of dimethyl sulfoxide, dimethyl formanfide and dimethyl acetamide on the cutaneous barrier to water in human skin, J. Invest. Derrnatol., 50, 283 (1968). McDermot, H. L., Finkbeiner, A. J., Wells, W. J., and Heggie, R. M., The enhance- ment of penetration of an organophosphorus anticholinesterase through guinea pig skin by dimethyl sulfoxide, J. Physiol. Pharmacol., 45, 299 (1967) Kligman, A.M., Topical pharmacology and toxicology of dimethyl sulfoxide, J. Am. Med. Assoc., 193, 796 (1965). Rammler, D. H., and Zaffaroni, A., Biological implications of DMSO bascd on a review of its chemical properties, Ann. N.Y. Acad. Sci., 141, 13 (1967). Embery, G., and Dugard, P. H., The influence of dimethyl sulfoxide on the percutane- ous migration of potassium dodecyl (•S) sulphate, Brit. J. Dermatol., 81, Suppl. 4, 63 (1969). Scala, J., McOsker, D. E., and Reller, H. H., The percutaneous absorption of ionic surfactants, J. Invest. Dermatol., 50, 371 (1968). Blank, I. H., Cutaneous barriers, Ibid., 45, 249 (1965). Blank, I. H., and Gould, E. J., Penetration of anionic surafctants (surface active agents) into skin, Ibid., 33, 327 (1959). Blank, I. H., and Gould, E. J., Penetration of anionic surfactants into skin. III. Pene- tration from buffered sodium laurate solutions, Ibid., $7, 485 (1961). Bettley, F. R., The irritant effect of soap in relation to epidermal permeability, Brit. J. Dermatol., 75, 113 (1963). Wahlberg, J. E., The effect of anionic, cationic and nonionic detergents on the percu- taneous absorption of sodium chromate (•Cr) in the guinea pig, Acta Dermato-Ven- ereol., 48, 549 (1968). Bettley, F. R., The influence of detergents and surfactants on epidermal permeability, Brit. J. Derrnatol., 77, 98 (1965). Bettley, F. R., The influence of soap on the permeability of the epidermis, Ibid., 73, 448 (1961).