IMPACT OF SUNSCREEN REGULATIONS ON SUNCARE DEVELOPMENT 231 are being absorbed into our blood and are unsafe to use? Publishing their studies in JAMA without an alternative is a travesty that casted doubts on the current protocols in combating the rising incidence of skin cancer. We need options and real solutions now for adequate protection from the harmful radia- tion of the sun. We need new safer ingredients and protocols for sun protection. Let us start out with approving the tried and true European fi lters. Also, allow American ingenuity the opportunity and the path to introduce new effective and safe ingredients to combat the rising incidents of skin cancer. * Footnote: Since I wrote this article in January 2020, Congress released its Over-The- Counter Reform Act on March 25, 2020 as part of the 2 Trillion dollar stimulus package. For a review, please read my May and June "The Sunscreen Filter" column in HAPPI Magazine for all the recommendations pertaining to Sunscreens in the Reform Act. REFERENCES (1) Skin Cancer Foundation, www.skincancer.org/skin-cancer-information. (2) A. Holzer, M. Athar, and C. Elmets, The other end of the rainbow: infrared and skin, J. Invest. Dermatol., 130, 1496–1498 (2010). (3) C. Calles, M. Schneider, F. Macaluso, T. Benesova, J. Krutmann, and P. Schroederand, Infrared A radia- tion infl uences the skin fi broblast transcriptome: mechanism and consequences, J. Invest. Dermatol., 130, 1424–1436 (2010). (4) A. M. Calafat, L.-Y. Wong, X. Ye, J. A. Reidy, and L. L. Needham, Concentration of the Sunscreen Agent, Benzophenone-3, in Residents of the United States: National Health and Nutrition Examination Survey 2003– 2004. Environmental Health Perspectives 116 (2008). (5) https://www.federalregister.gov/documents/2019/02/26/2019-03019/sunscreen-drug-productsfor- over-the-counter-human-use. 21 CFR Parts 201,310, 347 and 352. (6) M. K. Matta, D. G. Strauss, R. Zusterzeel, N. R. Pilli, V. Patel, D. A. Volpe, J. Florian, L. Oh, E. Bashaw, I. Zineh, C. Sanabria, S. Kemp, and A. Godfrey, Effect of sunscreen application under maximal use conditions on plasma concentration of sunscreen active i ngredients, JAMA, 321, 2082–2091 (2019). (7) https://jamanetwork.com/journals/jama/article-abstract/2759002. (8) https://www.chemistryworld.com/news/hawaii-set-for-first-ever-ban-on-two-sunscreen-ingredients/ 3009002. (9) https://www.staradvertiser.com/2020/01/30/breaking-news/hawaii-bills-would-limit-more-than-a- dozen-chemicals-in-sunscreens/.

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