ANALYTICAL CHEMISTRY OF COSMETICS 419 (43) D. Grossi and R. Vece, The gas chromatographic analysis of primary, secondary, and tertiary fatty amines and of compounding quaternary ammonium compounds,J. Gas Chromatog., 3, 170 (1965). (44) R.J. Cotter, G. Hansen and T. R.Jones, Mass spectral determination of long chain quaternary amines in mixtures, Anal Chim. Acta, 136, 135-42 (1982). (45) N. N. Daoud, P. A. Crooks and P. Gilbert, Identification of component alkyl chains within commercial samples of benzalkonium chloride mixtures by chemical ionization mass spectrometry,J. Pharm. PharmacoL, 33, 8P (1981). (46) C. H. Wilson, Identification of preservatives in cosmetic products by thin layer chromatography,J. Soc. Cosmet. Chem., 26, 75-81 (1975). (47) D. H. Liem, Analysis of antimicrobial compounds in cosmetics, Cosmet. anal Toilet., 59, 59-62, 67-68, 70-72 (1977). (48) E. P. Sheppard and C. H. Wilson, Fluorometric determination of formaldehyde-releasing cosmetic preservatives,J. Soc. Cosmet. Chem., 25,655-666 (1974). (49) M. W. Dong andJ. L. DiCesare, Very high speed liquid chromatography. III. Quantitative analysis of parabens in cosmetic products,J. Chromatogr. Sci., 20, 49-54 (1982). (50) Y. Masada, Analysis of Essential Oils by Gas Chromatography and &lass Spectroscopy (John Wiley Be Sons, Inc., New York, 1976). (51) B.J. Gudzinowicz, M.J. Gudzinowicz, and H. F. Marten, Fundamentals of Integrated GC-&iS, VoL 7 (Marcel Dekker, Inc., New York, 1977). (52) W. Jennings and T. Shieamoto, Qualitative Analysis of Flavor anal Fragrance Volatiles by Glass Capillary Gas Chromatography (Academic Press, New York, 1980). (53) W. Paul and H. Steinwedel, Ein Neues Massenspektrometer Ohne magnetfeld, Z. Naturforschung, (8a), 448-450 (1953). (54) B. B. Jones, B.C. Clark, and G. A. Iacobucci, Semipreparative high-performance liquid chromato- graphic separation of a characterized flavor mixture of monoterpenes, J. Chromatog., 178, 575-578 (1979). (55) J. Fohlman, L. Rask, and P. A. Peterson, High pressure liquid chromatographic identification of phenylthiohydantoin derivatives of all twenty common amino acids, Anal. Biochem., 106, 22-26 (1980). (56) G.J. Hughs, K. H. Winterhalter, E. Boiler, and K.J. Wilson, Amino acid analysis using standard high performance liquid chromatography,J. Chromatogr., 235,417-426 (1982). (57) D. W. Hill, F. H. Walters, T. D. Wilson, and J. D. Stuart, High performance liquid chromatographic determination of amino acids in the Picomole range, Anal. Chem., 51, 1338-1341 (1979). (58) S. I. Bonvell and R. H. Monheimer, A gas-liquid chromatographic analysis of sulfur-containing amino acids employing flame photometric detection,J. Chromatogr. Sci., 18, 18-22 (1980). (59) J. J. Hansen, T. Greibrokk, B. L. Currie, K. Nils-Gunnar Johansson, and K. Folkers, High pressure liquid chromatography of peptides,J. Chromatogr., 13 5, 155-164 (1977). (60) W. S. Hancock, C. A. Bishop, R. L. Prestidge, and D. R. K. Harding, High pressure liquid chromatography of peptides and proteins. II. The use of phosphoric acid in the analysis of underivatized peptides by reverse phase high pressure liquid chromatography, J. Chromatogr., 153, 391-398 (1978). (61) F. E. Regnier and K. M. Goodin& High performance liquid chromatography of proteins, Anal. Biochem., 103, 1-25 (1980). (62) T. Hashimoto, H. Sasaki, M. Aiura, and Y. Kato, High speed aqueous gel-permeation chromatogra- phy of proteins,J. Chromatogr., 160, 301-305 (1978). (63) B. A. Coles, Protein determination by nuclear magnetic resonance,J. Am. Oil Chem. Soc., 57, 202-204 (1980). (64) I. J. Levy and P. L. Dubin, Molecular weight distribution of cationic polymers by aqueous gel permeation chromatography, Ind. Eng. Chem. Prod. Res. Deve., 21, 59-63 (1982). (65) "N-nitroso compounds--analysis and formation," IARC Scientific Publication No. 3, International Agency for Research on Cancer, Lyon, France, 1972. (66) "Environmental N-nitroso compounds--Analysis and formation," IARC Scientific Publication No. 14, International Agency for Research on Cancer, Lyon, France, 1976. (67) T. U. Fan, U. Goff, L. Song, D. H. Fine, G. P. Arsenault, and K. Biemann, N-nitrosodiethanolamine in cosmetics, lotions and shampoos, Food Cosmet. Tox., 15,423-430 (1977). (68) MRI Reports NFT-1-NFT-7. Available through the Cosmetic, Toiletry and Fragrance Association, 1110 Vermont Avenue, N.W., Washington, D.C. 200O5.

42O JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS (69) P. Rahn and W. Mitchell, High performance liquid chromatography in cosmetic analysis, Drug Cosmet. Indus., 123, 56-66, 126, 130 (1978). (70) I.E. Rosenberg, J. Gross, T. Spears, and U. Caterbone, Methodology development for the determination of nitrite and nitrosamines in cosmetic raw materials and finished products, J. Soc. Cosmet. Chem., 30, 127-135 (1979). (71) I.E. Rosenberg, J. Gross, T. Spears, and P. Rahn, Analysis of nitrosamines in cosmetic raw materials and finished product by high pressure liquid chromatography, J. Soc. Cosmet. Chem., 31, 237-252 (1980). (72) I.E. Rosenberg,J. Gross, and T. Spears, Analysis of N-nitrosodiethanolamine in linoleamide DEA by high pressure liquid chromatography and U.V. detection,J. Soc. Cosmet. Chem., 31,323-327 (1980). (73) Y. Fellion, J. DeSmedt, and N. Brudney, "An HPLC-UV method for the direct evaluation of N-nitrosodiethanolamine in some cosmetic products and raw materials, N-nitroso compounds analysis, formation and occurrence," IARC Scientific Publication No. 31, International Agency for Research on Cancer, Lyon, France, 1980, pp 435-444. (74) M. Tunick, H. S. Veale, and G. W. Harrington, Qualitative detection of N-Nitrosodiethanolamine in cosmetic products, Fd. Chem. Toxic., 20, 473-474 (1982). (75) H.J. Chou, R. L. Yates, R.J. Gajan, and H. M. Davis, Differential pulse polarographic determination of N-nitrosodiethanolamine in cosmetic products,J. Assoc. Off. Anal. Chem., 65(4), 850-854 (1982). (76) R. H. Bennett and E. S. Peterson, "Determination of nitrosamines by liquid chromatography using a photoconductivity detector," Paper presented at the 21st Rocky Mountain Conference on Analytical Chemistry, August 2, 1979, Denver, CO. (77) S.S. Hecht and J. B. Morrison, N-nitroso-N-methyldodecylamine and N-nitroso-N-methyltetrade- cylamine in hair care products, Fd. Chem. Tox., 20, 165-169 (1982). (78) V. H. Baptist and R. Brown, Nitrosamine determination by the use of conventional equipment,J. Soc. Cosmet. Chem., 31,219 (1980). (79) I. Schmakz, S. Abidi, and D. Hoffman, Tumorigenic agents in unburned processed tobacco: N-nitrosodiethanolamine and 1,1-dimethylhydrazine, Cancer Letters, 2, 125-132 (1977). (80) P. Griess, Bernerkungen zu der Abhandlung der H. H. Weselsky und Benedikt: 'Ueber einige azovervindungen,' Bet. Dtsch. Chem. Ges., 12,426-428 (1879). (81) R. R. Gadde and B. Patel, A simple nitrite assay method for the screening of raw materials commonly used in creams and lotions,J. Soc. Cosmet. Chem., 30, 385-391 (1979). (82) J. H. Wiersma, 2,3-Diaminonaphthalene as a spectrophotometric and fluorometric reagent for the determination of nitrite ion, Anal. Letters, 3(3), 123-132 (1970). (83) MRI Reports NFT-10 NFT-11. Available through the Cosmetic, Toiletry and Fragrance Association, 1110 Vermont Avenue, N.W., Washington, D.C. 20005. (84) T. Birkel, C. Warner, and T. Fazio, Gas chromatographic determination of 1,4-Dioxane in Polysorbate 60 and Polysorbate 80, J.H.O.Ac., 62, 931-936 (1979). (85) Report of the Dioxane Round-robin Program. Available through the Cosmetic, Toiletry and Fragrance Association, 1110 Vermont Avenue, N.W., Washington, D.C. 20005. (86) B. A. Waldman, Analysis of 1,4-dioxane in ethoxylated compounds by gas chromatography/mass spectrometry using selected ion monitoring,J. Soc. Cosmet. Chem., 33, 19-25 (1982). (87) J. j. Robinson and E. W. Ciurczak, Direct gas chromatographic determination of 1,4-dioxane in ethoxylated surfactants,J. Soc. Cosmet. Chem., 31,329-337 (1980). (88) M. L. Stafford, K. F. Guin, G. A.Johnson, L. A. Sanders, and S. L. Rockey, Analysis of 1,4-dioxane in ethoxylated surfactants,J. Soc. Cosmet. Chem., 31,281-287 (1980). (89) E. K. Weisburger et al., Testing of twenty-one environmental aromatic amines or derivatives for long-term toxicity or carcinogenicity, J. Environ. Path. and ToMcol., 2, 325-356 (1978). (90) E. Cox, High performance liquid chromatographic determination of quinizarin, p-toluidine and D & C Violet No. 2 in D & C Green No. 6, J.A.O.Ac., 62, 1338-1341 (1979). (91) Federal Register, 47, No. 64, 14140 (1982).