280 JOURNAL OF COSMETIC SCIENCE the skin. We were able to show that 1 % Sodium Ascorbyl Phosphate has a strong anti-microbial effect with a log reduction of 5 after 8 hours on P. acnes in a time-kill study. Further on in a human in vivo study with 20 subjects a Sodium Ascorbyl Phosphate O/W formulation si gn ificantly prevents the UV A-induced sebum oxidation up to 40%. Finally we performed an open in vivo study with 60 subjects with a 5% Sodium Ascorbyl Phosphate lotion over 12 weeks. The efficacy ranked as excellent and good of Sodium Ascorbyl Phosphate was 76.9%, which was superior compared with a widely prescribed acne treatment. In conclusion this data shows that Sodium Ascorbyl Phosphate is efficient in the prevention and treatment of acne vulgaris. Sodium Ascorbyl Phosphate can be used in a non-antibiotic and effective treatment or co-treatment of acne with no side effects, which makes it particularly attractive for cosmetic purposes. Synthesis of mono-dispersed spherical silica particles containing covalently bonded chromophores Thomas Walenzyk, Christophe Carola, Herwig Buchholz and Burkhard Konig Institut fi.ir Organische Chemie, Universitat Regensburg, Regensburg, Germany Organic-inorganic UV active hybrid materials have been prepared by a sol-gel process from benzophenone derivatives and tetraethylorthosilicate. The silica particles are spherical in shape and have a narrow size distribution which remains unchanged up to organic chromophore concentrations of 0.2 mmol/g. At higher concentrations the spheres become less regular and fuse. A dependence of the materials absorption properties on the particle size (at the same organic chromophore concentration) and on the concentration of surface grafted chromophores was noted. The most effective UV filter materials were found in a combination of silica incorporated chromophores and surface grafted chromophores at low overall chromophore concentration. A comparison of the chromophores photostability at standardized UV irradiation revealed an increase in stability for silica incorporated and surface immobilised benzophenone compared to benzophenone in homogeneous solution. Topical palmitoyl pentapeptide provides improvement m photoaged human facial skin Larry R. Robinson, Noelle C. Fitzgerald, Darrell G. Doughty, Nancy C. Dawes, Cynthia A Berge, and Donald L. Bissett The Procter & Gamble Company, Miami Valley Laboratories, Cincinnati, OH, USA The palmitoyl pentapeptide palmitoyl-lysine-threonine­ threonine-lysine-serine (pal-KTTKS) is a synthetic material that was designed as a topical agent to stimulate collagen production and thus provide a skin anti-wrinkle benefit. To determine if pal-KTTKS is effective, the clinical study reported here was conducted. Caucasian female subjects (n = 93, ages 35-55) participated in a 12-week, double-blind, placebo-controlled, split-face, left-right randomized clinical study assessing two topical products: moisturizer control product vs. the same moisturizer product containing 3 ppm pal-KTTKS. Pal-KTTKS was well tolerated by the skin and provided significant improvement vs. placebo control for reduction in wrinkles/fine lines by both quantitative technical and expert grader image analysis. In self assessments, subjects also reported si gn ificant fine line/wrinkle improvements and noted directional effects for other facial improvement parameters.
]. Cosmet. Sci.J 56, 281-282 Quly/August 2005) Abstracts IFSCC Magazine Vol. 8, No. 2, 2005* Emotional and Psychological Effects of Fra gr ance in Men's Modified Superoxide Dismutase for Cosmeceuticals Skin Care A. Abriat 1 , S. Barkat 2 , M. Bensafi 2 , C. Roub/• 3 , V. Guillou 4 1 Lancome, Paris, France 2 Neurosciences et System.es Sensoriels, CNRS UMR 5020, Universite Claude Bernard Lyon 1 , France 3 INRA UMR Aromes, Dijon, France 4 L 'Orea! Recherche, Chevilly - Larue, France It has been demonstrated for visual and olfactory stimuli that an increase in heart rate, skin conductance, facial electromyogram activity and breathing rate correlates with negative and/or excited emotional states and a decrease with positive and/or relaxed emotional states. It was the aim of this study to explore the psychophysiological status of emotional moods associated with use of a men's skincare range. Therefore, in a five-day habituation phase nineteen male volunteers (mean age 32 years) used three perfumed products (a shaving mousse, cleansing gel and hydrating cream) for their morning shaving routine and assessed their mood before and after by means of self-assessment manikins and a general mood estimate questionnaire. In a second study phase the psychophysiological parameters heart rate, skin conductance and facial electromyogram activity of the resting subjects were recorded after exposure to three different odors, the fra gr ance of the men's products of the habituation phase, a control fragrance and the solvent dipropylene glycol. During the habituation phase the cosmetics had positive effects on the mood behavior of the subjects. These positive effects could be confirmed by the objective measurements of peripheral nervous system parameters in the.second study phase. Nae-Gyu Kang, Jun-l'vfan Lim, Min-You! Chang, Sun-Gyoo Park, Wan-Goo Cho, and Soo-Y oung Choi 1 LG Household & Health Care Research Park, Yusong-gu, Daejon, Korea 1 Deparment of Genetic Engineering, Division of Life Sciences, Hallym University, Chunchon, Korea A human Cu,Zn-superoxide dismutase was fused with a transcriptional transactivator protein transduction domain of HIV-1 to produce a novel anti-aging in gr edient for cosmeceuticals, transcriptional transactivator superoxide dismutase (Tat-SOD). Stability tests and evaluation of the transduction efficacy and enzymatic activity suggest Tat­ SOD is an effective active in gr edient for anti-aging treatment. A Look Behind the Salt Curve: The Link Between Rheology, Structure, and Salt Content in Shampoo Formulations Kevin Penfield, Ph.D. Uniqema, 900 Uniqema Blvd., New Castle, DE 19720-2779, USA The salt curve is well documented in the literature, whereby the viscosity of a solution initially increases with the addition of salt but then decreases with further increases in salinity. This paper examines the rheological behavior of eight common shampoo bases made with sodium lauryl ether * These abstracts appear as they were originally published. They have not been edited by the Journal of Cosmetic Science. 281
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