114 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS (lO) (11) (12) (13) (14) (15) (16) (17) Train, D. J., Y. Pharm. Pharmacol., 10, 127T (1958). Grosby, E. J., Am. Perfurner, 75 (Sept.), 43 (1960). Tawashi, R., Pharm. Ind., 25, 64 (1963). Tawashi, R., Diss., Basel, 1960. Gregg, S. J., The Surface Chemistry of Solids, 2nd Ed., Chapman and Hall Ltd., London, 1961. Coulson, J. M., and Richardson, J. F., Chemical Engineering, Vol. II, Pergamon Press, London, 1962, p. 854. Roemer, G., Dranoif, J. S., and Smith, J. M., Ind. Eng. Chem., Fundamentals, 1, 284 (1962). Krasuk, J. H., and Smith, J. M., Ibid., 4, 102 (1965).
J. Soc. Cosmetic Chemists, 17, 115-122 (1966) Aqueous Topical Adhesives Spray-on Bandage II. WINTHROP E. LANGE, Ph.D., and VICTOR S. FANG, M.S.* Presented December 2, 1963, New York Uity Synopsis--The research and development of protective films for cosmetic and dermatological uses have been of interest to many groups in recent years. Many of these preparations in pressurized packaging are known as "spray-on bandages." They usually deposit film on the skin which cannot be readily washed off. Thus the development of a preparation con- taining water-washable resins was considered advantageous. A combination of polyvinyl alcohol with either polyvinyl acetate or acrylic resins pro- duced aerosol concentrates with good stability and film-forming properties. Incorporation of the concentrates into quick-breaking foam formulations gave products with good stability and bandage properties. The products when sprayed on the skin dried to transparent, tack- free films in approximately 10 minutes. INTRODUCTION The research and development of medicated films for cosmetic and dermatological uses have been topics of great interest in recent years. Many of these preparations in pressurized packaging are known as "spray-on bandages." They are generally two-phase aerosols con- taining plain or medicated resin dressings, an organic solvent, and a propellant. Although these products have been widely accepted be- cause of their convenience, they have some shortcomings. They usually deposit a film on the skin which cannot be washed off. The organic solvent systems prevent the incorporation of drugs which are soluble only in water. * Massachusetts College of Pharmacy, Boston, Mass. 115
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