g80 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS (1) (2) (3) (4) (5) (6) (7) (8) (9) (10) (11) (12) (13) (14) (15) (16) (17) (18) (19) (20) (21) (22) (23) (24) (25) (26) (27) (28) (29) (30) (31) REFERENCE s Nevins, M. A., Stechel, G. H., Fishman, S. I., Schwartz, G., and Allen, A. C., Pul- monary granulomatosis. Two cases associated with inhalation of cosmetic aerosols, J. Amer. Med. Ass., 193, 86-91 (1965). DeNosaquo, N., Hair sprays and blood dysrasias, Ibid., 188, 197 (1964). Bergmann, M., Flance, I. J., and Blumenthal, H. T., Thesaurosis following inhalation of hair spray. A clinical and experimental study, N. Engl. J. Med., 258, 471-6 (1958). Kramer, R. A., and Pierpaoli, P., Hallucinogenic effect of propellant components of deodorant sprays, Pediatrics, 48, 322-3 (1971). MacLean, A. L., A common epithelial keratitis from noncorrosive household sprays, Trans. Amer. Acad. Ophthalmol. Otolaryngol., 71, 330-40 (1967). Masters, E. J., Allergies to cosmetic products, N.Y. State J. Med., 60, 1934-40 (1960). Gowdy, J. M., Feminine deodorant sprays, N. Engl. J. Med., 287, 203 (1972). Kaye. B. M., Hazards of hygenic deodorant sprays for women, J. Amer. Med. Ass., 212, 2121 (1970). MacLean, A. L., Aerosol keratitis, a common epithelial foreign body reaction to household chemical sprays, Amer. J. Ophthalmol., 63, 1709-19 (1967). Zucker, A., Investigation of purified pyrethrum extracts, Ann. Allergy, 23, 335-39 (1965). Teitelbaum, D. T., Vegetable oil aerosol spray intoxication, Rocky Mr. Med. J., 66, 62-3 (1969). Bernstein, I. L., Medical hazards of aerosols, Postgrad. Med., 52, 62-77 (1972). Sulzberger, M. B., Warshaw, T., and Herrmann, F., Studies of skin hypersensitivity to lanolin, J. Invest. Dermatol., 20, 33 (1953). Gloxhuber, C., Phototoxicity testing of cosmetic materials, J. Soc. Cosmet. Chem., 21, 825-33 (1970). Keri, H., Contact dermatitis due to oil of citronella, J. Invest. Dermatol., 8, 327 (1947). Osbourn. R. A., Tusin•, T. W., Coombs, F. P., and Moorish, E. P., Dermatologic standardization of perfumes, N.Y. State J. Med., 57, 1069 (1957). Birmingham, D. J., Clinical aspects of cutaneous irritation and sensitization, Toxicol. Appl. Pharmacol., 7, 54-9 (1965). Spoor, H. J., Skin reactions to cosmetics-classification and diagnosis, N.Y. State J. Med., 60, 1940-6 (1960). Rand, M. J., Toxicological considerations and safety testing of cosmetics and toiletties, Amer. Cosmet. Perrum., 87, 39-48 (1972). Jacobi, O., More on skin respiration and cosmetics, Ibid., 85, 25-30 (1970). Taylor, G. J., and Harris, W. S., Cardiac toxicity of aerosol propellants, J. Amer. Med. Ass., 214, 81-5 (1970). Editorial, Cardiac toxicity of aerosol propellants, Ibid., 222, 827-9 (1972). Egle, J. L., Putney, J. W., and Borzella, J. F., Cardiac rate and rhythm in mice af- fected by haloalkane propellants, Ibid., 222, 786-9 (1972). Tronnier, H., Cosmetic agents for general skin care and for feminine hygiene: der- matologists viewpoint, Seifen-Oele-Fette-Wachse, 96, 794-7 (1970). Ph•tsicians Desk Reference to Pharmaceutical Specialties and Biologicals, Medical Economics, Inc., Oradell, N.J., 1972, pp. 1374-5. Sterling, G. M., and Batten, J. C., Effect of aerosol propellants and surfactants on airway resistance, Thorax, 24, 228-31 (1969). Editorial, Cardiac toxicity of aerosol propellants, J. Amer. Med. Ass., 214, 136 (1970). Reinhardt, C. F., Azar, A., Maxfield, M. E., Smith, P. E., and Mullin, L. S., Cardiac arrhythmias and aerosol sniffing, Arch. Environ. Health, 22, 265-79 (1971). Idson, B., Topical toxicity and testing, J. Pharm. Sci., 57, 1-11 (1968). Downing, R. C., and Madinabeitia, D., The toxicity of fiuorinated hydrocarbon aero- sol propellants, Aerosol Age, 5, 25-8 (1960). Aerosol Education Bureau, Warning against deliberate misuse of aerosol products, Amer. Cosmet. Perrum., 87, 53-4 (1972).

CURRENT PERSPECTIVES ON AEROSOL TOXICITY 281 (32) (33) (34) (35) (36) (37) (38) (39) (40) (41) (42) (43) (44) (45) (46) (47) Clayton, J. W., The toxicity of fiuorocarbons with special reference to chemical con- stitution, Freon Tech. Bull. S-22. Clayton, J. W., Fluorocarbon toxicity and biological action, Fluorine Chem. Rev., 1, 197-252 (1967). Wiberg, G. S., Evaluating the toxicology of household aerosols, presented at the Society of Toxicology, 11th Annual Meeting, March 1972. McClure, D. A., Failure of fiuorocarbon propellants to alter the electrocardiogram of mice and dogs, Toxicol. Appl. Pharmacol., 22, 221-30 (1972). Azar, A., Zapp. ]. A., Jr., Reinhardt, C. F., and Stop,ps, G. J., Cardiac toxicity of aerosol propellants, 1. Amer. Med. Ass., 215, 1501-2 (1971). Flowers, N. C., and Horan, L. G., Nonanoxic aerosol arrhythmias, Ibid., 219, 33-7 (1972). Rubin, J., Slepyan, A. H., Weber, L. F., and Neuhauser, I., Granulomas of the axilla ca •sed by deodorants, Ibid., 162, 953-5 (1956) Asby, N., Consumerists and feminists vs. the vaginal spray, Product Management, 30-4 (March 1973). Medical News, Feminine hygiene sprays controversial despite FDA action, J. Amer. Med. Assoc., 219, 449-52 (1972). Parisse, A. J., Recent changes in formula technology of aerosol personal products, Amer. Cosmet. Perrum., 86• 46-8 (1971). Brtmner, M. J., Giovacchini, R. P., Wyatt, J.P., Dunlap, F. E., and Calandra, J. C., Pulmonary disease and hair-spray polymers: a disputed relationship, J. Amer. Med. Assoc., 184, 851-7 (1963). Calanalta, J., and Kay, J. A., Inhalation of aerosol hair sprays, Drug Cosmet. Ind., 84, 174-7 (1959). Giovacchini, R. P., Becker, G. H., Brunner, M. J., and Dunlap, F. E., Pulmonary disease and hair-spray polymers: effects of long term exposure of dogs, I. Amer. Med. Ass., 193, 298-9 (1965). John, H. A., Thesaurosis: a survey of those at risk, Med. 0t•ice, 109, 399 (1963). McLaughlin, A. I. G., Bidstrup, P. L., and Konstam, M., The effects of hair lacquer sprays on the lungs, Food Cosmet. Toxicol., 1, 171-88 (1963). Larson, R. K., A study of midexpiratory flow rates in users of hair spray, Amer. Rev. Resp. Dis., 90, 786-8 (1964).