618 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS Figure 6. Scanning electron micrograh of water-soaked skin. Wolfram, Wolejsza and Laden (8). Bar represents 167 t•m simultaneously enhancing the roughness and bumpiness within each cluster (Fig. 6). Ether extraction followed by water elution causes a further elevation in the height and number of protuberances ( Fig. 7). The grooves between [he subdivisions spread and have become accentuated, while the surface has be- come stretched and made taut. These SEM observations (8) strongly sub- stantiate the conclnsion drawn from gravimetric (1, 2) and biomechanical (7-9) analyses that removal of lipids and NMF results in enhanced water
ASSESSMENT OF SKIN MOISTURIZATION 619 '% .... ' ":::•' .--c.':.::,--..•. . . . : ......... .... -'-' •:ii:. ".• '"L .•-::'.)'(-• ":'":" ß :: •½ . --. .... .•- •:•--.• -•½:•d. --..:'.:..'..:½.:•.:•.-•..:.:-/.-:"'::"......'" '::'' ' •": ..' •.•.".::.•:'*•5•-': ß . ½' '-- , .,::..' ..:.. ß / ../ .... ... ........ .. •. .... -: /-- .:.........• . •.. ß '-.' ß .• •Z. •-t •. -.':.. : '"..:: ".':.. .- . ] -•{•..'•..' :,•:::•--.•.-- ..- . -.•.,-•"• ....:•...-:. :,' _:. --• .. . •:: -- . : •"•:. . :-,....': ..•: '..--:...•.• •:. %..:--,:,.:.:.-.".'. :-... •....--: : -:"%"'.• •.:..• '%:."':':." ':' '-'":%d'.. ..? •..•-: "•::-:.:'•.•-• '•:.'½• . "•. '::'" . •.. .. ' •:: . "::' •:•'%..:• •:.':'.:.:::.' "•" :'•'• .-.•:s:: .-' .... ""-:"" '-' --'•':' '"' ..... . :. :%: .':., .:. :.:-': ...•:•'.•..•:• ...... ..:::':--•::.:.::•,.•. "•7.'. •':.: •.:.•:-:..?.,: •' •"':•-.- '•½ ..... :.•%•,•.•' '•f• •..•.. ...::ii:.. %.:?-•.:•.... ..• -:.. •....•- .•:.%..•.•'•-:•:.• % -'• ß '.• . : . .... (.........•½•.- ....... •. ...• .... . . . :--•..• ..• ..... •.. .::.. •: .. ..: •..•.•... ........ .. •., .•'•..• . ß •¾..:•' .:..•:• '....•' .'. •' ':.:•:' :•: :' •:%:-::" .... :•,•7 '.."..•: :.•. ,..• ß ::'•. ' ....... ' •:::.• •' .:d •::•:' •"• '• .....•. :"• '"'.•.:: •.:•.... ..:•. .• ,:•::: ..., :. •..'•½.'•.• '•••,•? ...:.• •:•-• :, .. .•:.. .... ,. ...•.• •:,,.. •*.. •'.: ::•: :•. ..•..:: ..... :.? •g'. .. ...::.:.. .... , ½. ß .... .:,. .... •,.:..% ,.......•... ...•.:....:..•..• -,• ..: ........... ..,. ½ .... ..:.:• : .•.•: .,•::...•:.½• -..:- . . .• .. :•:i..•:,'. •" . .... . ............ ...::::..:..•..,... .... ß --"- ..... " ' .. ß . .:-'.% '•.'• d':..:.-•:%:-. '" •.½ - k .• -- :- . '•--.:.." " "'" ½.:,.•....t- ..•'-:•.?"'"q& 2z. ...... •..' .'•'"{. (: .' "' :... "':: •:'.'".'." '--: " '"-2 ' .:,'•:- . . .... .: ..•...- .. •:::.?-. ..... -:.. •. .... ..... :. '.:-..' -.q.....::. -'•.. ....... :'"".":.. •?'.' '"':"' ".:':'.• 5?..•&:. '•:" '"• .. ?.. ..........:.:• .... ?..::. ? ?% ..=,., %: .. . •: ... ?•. ß . ........ ....:. ...::....: :.-.. ß :•..•, ..... •....•., ?•.•: ... ..... .-,. ß . .•. ..., ... :*g .. .•. .-- •. ....: ',:..:'..%. .: .•.• •: . .-.: .. ""' .-..'..-:.%• : •. d' '?'•--dCe.. •,.:,:.......,-:,:..:....:.,..:.,... ...,•½•..: ß ': " ,::. •.:,: •-•d•w•::... :.• :'--,•%d.:•::. ... . ...•: %.•-.:•:: :•"--•..•- :.'•:-,'::....... .... ...... .•: 2, s. •' '. --:• :.. .. ß 4..•- .•.. '"' v...'.'•-..-._•' ß . , ...:- /. ......,:• ..... .•.½ .. .•.. :• . .... ..':.:-., .... ,. - ,, ?:-: -" '•' ..:"• :. ½: : 2.'::47 ½ ..' ]: ..,-:• ' ' ' ?.::•.::'• t•':.½' --' .... •.' -.:. '" •.:'"":'•"*' :::• ........ :• :--':-?•" ß ":""':'"': '. : :' :• "*':': ...... . '7 .... '.-:.'. ' '":: •":'•½-'..5•.-.•.' '"." :' .,,-:k ." '%.•.. •'"." .:? . ..:• . : :.t:: , .... •.. '.'.• .. ':::•t..- * : :....., :':%: Figure 7. Scanning electron micrograph of ether-extracted and water-soaked skin. Wolh-am, Wolejsza and Laden (8). Bar represents 167/•m permeability, roughness, and swelling of the corneum cells concomitant with a weakening of the cellular membranes. This swelling, however, disappears within 1 h. In order to avoid removal of desquamous material from winter-dried skin through adhesion to the Silastic polymer upon repetitive replication of a single area, we have routinely chosen to reproduce immediately adjacent
Previous Page Next Page

Volume 27 No 12 resources

Extracted Text (may have errors)

618 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS Figure 6. Scanning electron micrograh of water-soaked skin. Wolfram, Wolejsza and Laden (8). Bar represents 167 t•m simultaneously enhancing the roughness and bumpiness within each cluster (Fig. 6). Ether extraction followed by water elution causes a further elevation in the height and number of protuberances ( Fig. 7). The grooves between [he subdivisions spread and have become accentuated, while the surface has be- come stretched and made taut. These SEM observations (8) strongly sub- stantiate the conclnsion drawn from gravimetric (1, 2) and biomechanical (7-9) analyses that removal of lipids and NMF results in enhanced water
ASSESSMENT OF SKIN MOISTURIZATION 619 '% .... ' ":::•' .--c.':.::,--..•. . . . : ......... .... -'-' •:ii:. ".• '"L .•-::'.)'(-• ":'":" ß :: •½ . --. .... .•- •:•--.• -•½:•d. --..:'.:..'..:½.:•.:•.-•..:.:-/.-:"'::"......'" '::'' ' •": ..' •.•.".::.•:'*•5•-': ß . ½' '-- , .,::..' ..:.. ß / ../ .... ... ........ .. •. .... -: /-- .:.........• . •.. ß '-.' ß .• •Z. •-t •. -.':.. : '"..:: ".':.. .- . ] -•{•..'•..' :,•:::•--.•.-- ..- . -.•.,-•"• ....:•...-:. :,' _:. --• .. . •:: -- . : •"•:. . :-,....': ..•: '..--:...•.• •:. %..:--,:,.:.:.-.".'. :-... •....--: : -:"%"'.• •.:..• '%:."':':." ':' '-'":%d'.. ..? •..•-: "•::-:.:'•.•-• '•:.'½• . "•. '::'" . •.. .. ' •:: . "::' •:•'%..:• •:.':'.:.:::.' "•" :'•'• .-.•:s:: .-' .... ""-:"" '-' --'•':' '"' ..... . :. :%: .':., .:. :.:-': ...•:•'.•..•:• ...... ..:::':--•::.:.::•,.•. "•7.'. •':.: •.:.•:-:..?.,: •' •"':•-.- '•½ ..... :.•%•,•.•' '•f• •..•.. ...::ii:.. %.:?-•.:•.... ..• -:.. •....•- .•:.%..•.•'•-:•:.• % -'• ß '.• . : . .... (.........•½•.- ....... •. ...• .... . . . :--•..• ..• ..... •.. .::.. •: .. ..: •..•.•... ........ .. •., .•'•..• . ß •¾..:•' .:..•:• '....•' .'. •' ':.:•:' :•: :' •:%:-::" .... :•,•7 '.."..•: :.•. ,..• ß ::'•. ' ....... ' •:::.• •' .:d •::•:' •"• '• .....•. :"• '"'.•.:: •.:•.... ..:•. .• ,:•::: ..., :. •..'•½.'•.• '•••,•? ...:.• •:•-• :, .. .•:.. .... ,. ...•.• •:,,.. •*.. •'.: ::•: :•. ..•..:: ..... :.? •g'. .. ...::.:.. .... , ½. ß .... .:,. .... •,.:..% ,.......•... ...•.:....:..•..• -,• ..: ........... ..,. ½ .... ..:.:• : .•.•: .,•::...•:.½• -..:- . . .• .. :•:i..•:,'. •" . .... . ............ ...::::..:..•..,... .... ß --"- ..... " ' .. ß . .:-'.% '•.'• d':..:.-•:%:-. '" •.½ - k .• -- :- . '•--.:.." " "'" ½.:,.•....t- ..•'-:•.?"'"q& 2z. ...... •..' .'•'"{. (: .' "' :... "':: •:'.'".'." '--: " '"-2 ' .:,'•:- . . .... .: ..•...- .. •:::.?-. ..... -:.. •. .... ..... :. '.:-..' -.q.....::. -'•.. ....... :'"".":.. •?'.' '"':"' ".:':'.• 5?..•&:. '•:" '"• .. ?.. ..........:.:• .... ?..::. ? ?% ..=,., %: .. . •: ... ?•. ß . ........ ....:. ...::....: :.-.. ß :•..•, ..... •....•., ?•.•: ... ..... .-,. ß . .•. ..., ... :*g .. .•. .-- •. ....: ',:..:'..%. .: .•.• •: . .-.: .. ""' .-..'..-:.%• : •. d' '?'•--dCe.. •,.:,:.......,-:,:..:....:.,..:.,... ...,•½•..: ß ': " ,::. •.:,: •-•d•w•::... :.• :'--,•%d.:•::. ... . ...•: %.•-.:•:: :•"--•..•- :.'•:-,'::....... .... ...... .•: 2, s. •' '. --:• :.. .. ß 4..•- .•.. '"' v...'.'•-..-._•' ß . , ...:- /. ......,:• ..... .•.½ .. .•.. :• . .... ..':.:-., .... ,. - ,, ?:-: -" '•' ..:"• :. ½: : 2.'::47 ½ ..' ]: ..,-:• ' ' ' ?.::•.::'• t•':.½' --' .... •.' -.:. '" •.:'"":'•"*' :::• ........ :• :--':-?•" ß ":""':'"': '. : :' :• "*':': ...... . '7 .... '.-:.'. ' '":: •":'•½-'..5•.-.•.' '"." :' .,,-:k ." '%.•.. •'"." .:? . ..:• . : :.t:: , .... •.. '.'.• .. ':::•t..- * : :....., :':%: Figure 7. Scanning electron micrograph of ether-extracted and water-soaked skin. Wolh-am, Wolejsza and Laden (8). Bar represents 167/•m permeability, roughness, and swelling of the corneum cells concomitant with a weakening of the cellular membranes. This swelling, however, disappears within 1 h. In order to avoid removal of desquamous material from winter-dried skin through adhesion to the Silastic polymer upon repetitive replication of a single area, we have routinely chosen to reproduce immediately adjacent

Help

loading