550 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS (11) (12) (6) J. Medema and J. Houtman, Brunauer-Emett-Teller specific measurement of solids using krypton., Anal. Chem., 41, 209-11 (1969). (7) S. P. Harrold and B. A. Pethica, Thermodynamics of the adsorption of small mole- cules by proteins, Trans Faraday Soc., 54, 1876-84 (1958). (8) B. R. Choman, Detemaination of the response of skin to chemical agents by an in vitro procedure, J. Invest. Dermatol., 37, 263-71 (1961). (9) R. B. Kundsin and C. W. Walter, Investigations on adsorption of benzalkonium chlo- ride U.S.P. by skin, gloves and sponges., Arch. Surg. Chicago, 75, 1036-42 (1957). (10) M. E. Ginn, S.C. Dunn, and E. Jungem•ann, Contact angle studies on viable human skin: II. Effect of surfactant ionic type in pretreatment, J. Amer. Oil Chem. Soc., 47, 83-5 (1970). E. S. Cooperman, Protein hydrolysates as skin moisturizers, Amer. Cosmet Perrum., 87, •5-7 (1972). J. Facq, D. L. Kirk, and C. A. Bebell, Simple replica technique for the observation of human skin, ]. Soe. Cosynet. Chem. 15, 87-98 (1964).
1. Soc. Cosmet. Chem., 26, 551-571 (November 1975) Evaluation of Human Body Odors: Methods and Interpretations A. DRAVNm•S, Ph.D.* Synopsis-Annoying odors from various parts of the HUMAN BODY constitute cosmetic defects. COSMETIC TREATMENTS to remedy such defects may be based on the sup- pression of MALODORANT GENEBATION and EMISSION, on MODIFICATION OF ODOR CHARACTER, or on both of these approaches. Measurement of the efficacy of the treatments requires a source-adapted sample collection technique and the use of appropriate sensory or analytical methods. The following are described and illustrated in this paper: measurements of odor intensity utilizing 1-butanol reference scale mea- surements of the odor threshol.d using a dynamic dilution forced-choice triangle olfac- tometer and measurements of odor character change by a multidimensional scaling of odors using a 136-descriptor list and the chi-squared statistic. The analytical techniques include use of odorograms (odor-annotated gas chromatograms) and are primarily suited for the measurement of efficacy in the suppression of malodorant emission and the eval- uation o[ the persistence of fragrances in vivo. INTRODUCTION Excessive or annoying odors, which are caused by the emission of odorous substances from various parts of the human body, may be considered cosmetic defects. Various treatments are used to correct such defects. Antiperspirants cleansing agents, which may be reinforced by substances that suppress proli- feration of microorganisms and fragrances that modify the character of odor are some examples of materials utilized in odor-correcting treatments. The development of formulations and application schedules for human- body odor control requires methods which may be used to measure the ef- ficacy of the treatments. The objective of this paper is to enumerate both some presently used methods, together •vith their principles, and some ex- *Odor Sciences Center, lit Research Institute, 10 West Thirty-fifth Street. Chicago, Ill. 6O616. 551
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