PRODUCT STABILITY--PART I 147 single nonisothermal run which is considered to be equal to a complete stability study. Essentially, the sample is subjected to a programmed change of temperature-time conditions. Some function, then, which represents both temperature and concentration, is obtained from samples removed and analyzed during the run. Plotting of the function rs. time produces a straight line from which both the heat of activation and the specific reaction rate constant may be calculated. Rogers (16) also presented a similar accelerated storage testing technique in which both the heat of activation and the room temperature reaction rate constant could be obtained from analyses made on samples withdrawn while the temperature of the system was raised in accordance with a certain pro- gram. (Received October 27, 1965) REFERENCES (1) Farrer, K. T. H., Blochem. J., 39, 128 (1945). (2) Farrer, K. T. H., Ibid., 39,261 (194,5). (3) Farrer, K. T. H., Ibid., 41, 162 (1947). (4) Farrer, K. T. H., 41, 167 (1947). (5) Maeek, T. J., Feller, B. A., and Hanus, E. J., J. Am. Pharm. Assoc., Sci. Ed., 39,365 (1950). (6) Watanabe, A., J. Pharm. Soc. Japan, 59 (3), 52,218 (1939). (7) Watanabe, A., Ibid., 59 (7), 133,500 (1939). (8) Heirnlich, K. R., and Martin, A. N., J. Am. ]harm. Assoc., 3ci. Ed., 49,592 (1960). (9) Ooteghem, M. V., and Stcigcr, K., through M. Gulllot, Am. J. Hosp. JVharm., 17• 540 (1960). 10) Tootill, J.P. R., J. Pharm. Pharmacol., 13• 75T (1961). 11) Kennon, L., J. Pharm. Sci., 53• 815 (1964). 12) Lordi, N. G., and Scott, M. W., Ibid., 54,531 (1965). 13) Eriksen, S. P., Pauls, J. F., and Swintosky, J. V., J. Am. ]harm. Assoc., Sci. Ed., 47,697 (1958). 14) Eriksen, S. P., Irwin, G. M., and Swintosky, J. V., Ibid., 49,632 (1960). 15) Eriksen, S. P., and Stelmaeh, H., J. ]harm. Sci., 54, 1029 (1965). 16) Rogers, A. R., J. ]harm. Pharmacol., 15, 101T (1963).
148 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS International Federation of Societies of Cosmetic Chemists The Fourth Congress of the I. F. S.C. C. will take place in Paris in June, 1966. The "Soci•t6 Francaise de Cosmeto]ogie" has created a scientific Committee consisting of: Dr. Ir. Velon Ir. Jean Morelle Dr. Collin This Committee wishes to receive conference papers before January 31, 1966. Each paper can be typed in the original language of the speaker. The French Committee will take care of the translation in English, French and German. General Secretary Dr. P. A.M. E. van Velzen Scheveningseweg 62 The Hague, The Netherlands
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