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1. Soc. Cosmet. Chem., 25, 407-421 (August 1974) Polymerization into Human Hair CLARENCE ROBBINS, Ph.D.,* RICHARD CRAWFORD, Ph.D.,* D. W. McNEIL, B.S.* JULIUS NACHTIGAL, Ph.D.,* and GIUSEPPI ANZUINO, Ph.D. '• Synopsis-THIOGLYCOLIC ACID (TGA)-CUMENE HYDROPEROXIDE (CHP) and BISULFITE--CHP systems are described for po]ymerizing METHYL METHACRYLATE (MMA) in HUMAN HAIR. An ethanol-water solvent system was employed. Diffusion rate control appears to predominate over a variety of reaction conditions. The influence of reagent concentrations and so]vent effects on the reaction is also describe:]. POLY- MERIZATION is shown to occur more rapidly into either reduced-oxidized or bleached hair than into chemically unaltered hair. Partial hydrolysis of the hair fibers containing polymethyl methacrylate (PMMA) provides filament-like fragments, consisting primarily of PMMA, which were examined microscopically. INTRODUCTION Two manuscripts (1, 2) from our laboratories describing chemical reac- tions of human hair containing synthetic polymer have already been pub- lished. This paper describes the polymerization reaction used in our earlier work and some characteristics of the synthetic polymer isolated by hydrolyric methods. Additional references and background to vinyl polymerizations in keratin fibers may be found in the first two articles of this series. EXPERI1VIENTAL Materials Human Hair The keratin fibers used in this investigation were brown human hair,$ from European Caucasians, which were washed with 2% sodium lauryl sul- fate and rinsed thoroughly with deionized water. *Colgate-Palmolive Research Center, 909 River Road, Piscataway, N.J. 08854. This work was conducted at the Colgate-Palmolive Research Center where all correspondence should be addressed. ?Chatilion S.P.A., Largo Chatilion, Verce]li, Italy. Purchased froin De Meo Brothers, New York, N.Y. 4O7