lOO 100. JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS 50.0 10.0 5.0 1.0 0.5 O.1 O I 2 3 4 5 6 % CONCENTRATION Figure 14. Propoxylated ethyl p-aminobenzoate erythemal and tanning transmission versus concentration considered of no significance in this test. These results are shown in Table III. Propoxylated ethyl p-aminobenzoate compared favorably with two cormner- cial products when all three were res,ted simultaneously. Three sites on the volar part of the right arm were stripped to the glistening layer by repeated application of clear tape. The volar part of the ]eft arm was used for normal skin. Each of the test materials was applied once daily for 10 days under oc- clusion to the arms of the subjects. Clinical evaluations were made daily, using a 0 to 4 scale. The method is that developed by Klingman and Wooding (7). (4) Maximization Testing o[ Sensitizing Potential (8): No instance of con- tact sensitization was noted on 25 healthy adult male volunteers.

EVALUATION OF SUNSCREENING AGENT 101 Table III Results Subject Number Initials Stripped Skin Study Day 1 2 3 4 5 6 7 8 9 10 1 K.C. 2 L.L. 3 M.W. 4 G.I. 5 L.C. 6 M.R. 7 C.O. 8 E.S. 9 l.c. lO J.R. 0 0 0 0 i 0 0 0 0 0 0 0 i i i 0 0 0 0 0 0 i i 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 i i 0 0 0 0 0 0 0 0 0 i i 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 I I I 0 0 0 0 0 0 0 i I 0 0 0 0 0 'Material: 5 per cent Amerscreen P lotion. Table IV Irritancy Subtotal Inunction for 21 days Subject Day Number Numbers Initials i 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 L.L. 0 0 1 0 0 1 0 0 1 0 0 0 1 1 0 0 0 1 1 0 0 E.S. 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 T.S. 0 0 0 0 0 0 0 0 0 0 0 0 i 0 1 0 i i 0 i 0 M.M. 0 0 0 0 i 0 0 0 i 0 0 i 0 0 0 0 0 0 i 0 0 G.S. 0 0 0 0 0 0 i 0 0 0 0 0 0 0 i 0 0 0 0 I 0 J.C. 0 0 0 0 0 0 0 0 1 0 0 1 1 1 0 0 0 1 0 0 0 M.R. 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 1 C.O. 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 1 0 0 0 0 0 T.O. 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 1 0 J.D. 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 1 1 0 0 M.W. 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 K.G. 0 0 0 0 0 0 1 0 0 1 1 0 1 0 0 1 0 0 0 1 0 C.J. 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 L.C. 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 1 J.R. 0 0 0 0 0 1 0 0 0 0 1 0 1 0 0 1 0 0 0 0 0 R.J. 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 J.F. 0 0 0 0 0 0 0 0 0 I 0 0 0 0 0 0 0 0 0 0 1 L.I. 0 0 0 0 0 0 0 0 0 0 i 0 i 0 0 0 0 i i 0 0 R.H. 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1t.P. 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0