160 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS (9) (10) (11) (12) (13) (14) (15) (16) (17) (18) (19) (20) Peck, S. M., and Glick, A. W., Y. Soc. Cosmetic Chem., 7,530 (1956). Shelmire, J. R., J. Invest. Dermatol., 26,105 (1956). Laden, K., J. Soc. Cosmetic Chem., 13,455 (1962). Fox, C., et al., J. Soc. Cosmetic Chem., 13,263 (1962). Blank, J. H., Proc. Scl. Sect. Toilet Goods Assoc., 23, 19 (1955). Blank, J. H., J. Am. Med. Assoc., 164,412 (May, 1957). Flesch, P., Am. Perfumer &' Cosmetics, 77, 77 (October, 1962). Weitzel, G., Hoppe-Seylers Z. Physiol. Chem., 285, 220, 230 (1950) 287, 66, 254 (1951) 288, 174, 189,200, 251,266 (1951) :]01, 17, 26 (1955) Fette Seifen Anstrichmittel, 63,171 (1961). Jacobi, 0., Perfumery Essent. Oil Record, :]4, 35 (1963). Gregory, H., Shirley Inst. Mere., 20,163 (1946). Reinertson, R. P., and Wheatley, V. R., J. Invest. Dermatol., :]2, 49 (1959). Nicolaides, N., and Kellum, R. E., J. Am. Oil Chemists' Soc., 42, 8 (1965).

J, Soc, Uosmetic Uhemists, 18, 161-167 (Mar. 4, 1967) Clinical Evaluation of Bacteriostatic Soap in Diaper Dermatitis- Prophylaxis* EMANUEL DUBOW, M.D., F.A.A.P.,t LEO WINTER, JR., D.D.S.,• and BRUCE E. ELLICKSON, Ph.D.õ Presented September 20-21, 1966, Seminar, New York City Synopsis--A clinical study was conducted in the New York City area using 100 infants with a history of diaper rash but who were not suffering from diaper rash at the beginning of the study. Fifty infants were bathed with an antibacterial soap containing 0.75% hexachloro- phene and 0.75 • 3,4,4 •-trichlorocarbanilide 50 infants were bathed with the same soap with- out the presence of the antibacterial agents. In the case of the relatively common varieties of diaper rash, the severity and the incidence during the use of the antibacterial soap were significantly lower than that from the soap containing no antibacterial system. INTRODUCTION Diaper dermatitis continues to be one of the most common problems of pediatrics (1). At some time it occurs in almost all infants, and cases serious enough to warrant treatment account for 25% of all pediatric patients seen (2-4). This figure does not include the milder forms of irritation noted during well-baby checkups (5). The etiology of diaper dermatitis is not entirely clear, though it is estimated that over 90% are due to contact dermatitis resulting from * Contributed by Armour Grocery Products Co., a Division of Armour and Co., Chicago, Ill. • Diplomate, American Board of Pediatrics, 7 Lexington Ave., New York, N.Y. :• Leo Winter Associates, Inc., 211 E. 43rd St., New York, N.Y. õ Armour Grocery Pro•tlct• Go., 100 S. Wacker Dr., Chicago, Ill. 161