9,08 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS (7) (9) (10) (u) (i3) (i4) (i5) (16) 07) (is) (i9) (23) (24) (25) ½6) ½7) (28) (29) (30) (3i) (32) (33) Onken, H. D., and Moyer, C. A., The water barrier in human epidermis, Arch. Dermatol., 87, 584 (1963). Berenson, G. S., and Burch, G. E., Studies of diffusion of water through dead human skin, Arner. J. Trop. Med., 31, 849. (1951). Blank, I. H., Cutaneous barrier, J. Invest. Dermatol., 45, 249 (1965). Scheuplein, B. J., and Blank, I. H., Permeability of the skin, Physiol. Be,)., 51, 702 (i97i). Baker, H., and Kligman, A.M., Measurement o[ transepidermal water loss by elec- trical hygrometry, Arch. Dermatol., 96, 441 (1967). Burch, G. E., and Winsor, T., Rate of insensible perspiration locally through living and dead human skin, Arch. lntern. Med., 74, 437 (1946). Singer, E. J., and Vinson, L. J., The water-binding properties of skin, Proc. Sci. Sect. Toilet Goods Ass., 46, 29 (1966). Mali, J. W. H., The transport of water through the human epidermis, J. Invest. Dermatol., 27, 451 (1956). Matoltsy, A. G., Downes, A.M., and Sweeney, T. M., Studies of the epidermal wa- ter barrier. Part 2. Investigation of the chemical nature of the water barrier, Ibid., 50, 19 (1968). Wurster, D. E., and Kramer, S. F., Investigations of some factors influencing per- cutaneous absorption, J. Pharm. Sci., 50, 288 (1961). Buettner, K., Diffusion of water vapor through small areas of human skin in a normal environmeut, J. Appl. Physiol., 14, 269 (1959). Burch, G. E., and Winsor, T., Diffusion of water through dead plantar, palmar and dorsal human skin and through toe nails, Arch. Dermatol., 53, 39 (1944). De Long, C. W., Thompson, R. C., and Kornberg, I5. A., Percutaneous absorption of tritimn oxide, Amer. J. Roentgenol., Radium Ther. Nucl. Med., 71, 1038 (1954). Scheuplein, R. J., Mechanism of percutaneous absorption. I. Routes of penetration and the influence of solubility, J. Invest. Dermatol, 45, 334 (1965). Spruit, D., and Malten, K. E., Epidermal water-barrier formation after stripping of normal skin, 1bid., 45, 6 (1965). Cronin, E., and Stoughton, R. B., Percutaneous absorption. Regional variations and the effect of hydration and epidermal stripping, Brit. J. Dcrmatol., 74, 265 (1962). Vickers, C. F. H., Existence of a reservoir in the stratum comeurn, Arch. Dermatol., 88, 20 (1963). Fox, C., Tassoff, J. A., Bieger, M. M., and Deem, D. E., Modification of the water- holding capacity of callus by pretreatment with additives, J. Soc. Cosmet. Chem., iS, •.63 (1962). WursteL D. E., and Munies, I4., Factors influencing percutaneous absorption of methyl ethyl ketone, J. Pharm. Sci., 54, 554 (1965). Idson, B., Biophysical factors in skin penetration, ]. Soc. Cosmet. Chem., 22, 615 (1971). Fritsch, W. F., and Stoughton, B. B., The effect of temperature and humidity on the penetration of C" acetylsalicylic acid in excised human skin, J. Int•esC Derrnatol., 41, 307 (1963). Scheuplein, B., and Boss, L., Effects of surfactants and solvents on the permeability of the epidermis, J. Soc. Cosmet. Ghem., 21, 853 (1970). McKenzie, A. W., and Stoughton, B. B., Method for comparing percutaneous ab- sorption of steroids, Arch. DermatoL, 86, 608 (1962). Hall-Smith, S. P., "Polythene" coverings in dermatological treatment, Br•t. Med. J., •, 1233 (1962). Sulzberger, M. B., and Witten, V. H., Thin plastic films in topical dermatologic ther- apy, Arch. Dermatol,, 84, 1027 (1961). Witten, V. H., Stein, S. J., and Michaelides, P., Use of thin pliable film in selected dermatoses, Ibid., 87, 458 (1963). Jacobi, O., Hygroscopic properties and the wettability of keratin materials, Kolloid- Z., 114, 88 (1949).
WATEB AND THE SKIN 9,09 (34) (35) (36) (37) (38) (39) (4O) (41) (42) (43) (44) (45) (46) (47) (48) (49) (50) (51) (52) (53) (54) (55) (56) Jacobi, O., Water and water vapor absorption of the stratum corncure of the living hutnan skin, J. Appl. Ph•tsiol., 12, 403 (1958). Spier, H. W., and Pascher, G., Dic WasserlSslichen Bestandteil der peripheren Hornschicht (Hautoberfl5che) Allgemeines, Stickstoffhaltige Substanzen, Arch. Klin. Exp. Dermatol., 199, 411 (1955). Spier, H. W., and Pascher, G., Freie aminosSuren an der hautoberflache, Ibid., 200, 59 (1955). Spier, H. W., and Pascher, (3., Die Wasserlbslichen Bestandteil der peripheren Homschicht (Hautober•iche) Stickstoffreie S[iuren und Basen, 1bid., 201, 181 (1955). Pascher, G., Die WasserlSslichen Bestandteile der peripheren Hornschicht (Hauto- berfl•iche) a-pyrrolidoncarbons•ture, Ibid., 203, 234 (1956). Pascher, G., and Spier, H. W., Die Wasserlbslichen Bestandteile der peripheren Hornschicht (Hautoberflache}: die Ursache der Thermolabilitiit des Oberttachen-pH, Ibid., 203, 239 (1956). Pascher, G., yon Steinvuck, G., and Spier, H. W., Die WasserlSslichen Bestandteile der peripheren Hornschicht (Hautoberfi•iche) zur inhomogenen Verteilung von a- Amino Stickstoff, Milchs•iure, Chlorid, Kalium (und Natrium) im Stratum Disjune- turn, 1bid., 204, 140 (1957). Szakall, A., Ober die Eigenschaften, Herkunft und physiologischen Funktionen der die H-Ionenkonzentration bestimmenden Wirkstoffe in der verhornten Epidermis, 1bid., 201, 331 (1955). Szakall, A., Physiologische Prinzipien bet der Entwicklung wirksamer PrSparate zur Gesunderhaltung der Haut, unter besonderer Beriicksichtigung der Verhiitung von Beruflichen HautschSden, Arzneim.-Forsch., 7, 408 (1957). Blank, I. H., and Shappirio, E. B., Water content of the stratum corneton. III. Effect of previous contact with aqueous solutions of soaps and detergents, ]. lnvesL Dermatol., 25, 391 (1955). Middleton, J. D., The mechanism of water binding in stratmn comeurn, Brit. 1. Dermatol., 80, 437 (1968). Park, A. C., and Baddiel, C. B., Rh½ology of stratum eorneum II. A physico-chemi- ca1 investigation of factors influencing the water content of the corneum, 1. Soc. Cosmet. Chem., 23, 13 (1972). Flesch, P, Chemical basis of emollient function in horny layers, Proc. Sci. Sect. Toilet Goods Ass., 40, 12 (1963). Jelenko, C., Purification of the water-holding lipid of intact skin and burn eschar, Amer. Surg., 35, 864 (1969). Laden, K., and Morrow, R., Torsional measurements on skin, 1. Soc. Cosmet. Chem., 21, 417 (1970). Laden, K., and Spitzer, R., Identification of a natural moisturizing agent in skin, Ibid., 18, 351 (1967). Kligman, A.M., in Montagna, W., and Lobitz, W. C., Jr., The Epidermis, Academic Press, New York, 1964. Scheuplein, R. J., Analysis of permeability data for the case of parallel diffusion pathways, Biophys. 1., 6, 1 (1966). Scheuplein, R. J., and Morgan, L. J., "Bound-water" in keratin membranes mea- sured by a microbalance technique, Nature, 214, 456 (1967). Grice, K. A., and Bettley, F. R., Skin water loss and accidental hypothermia in psoriasis, ichthyosis and erythroderma, Brit. Med. 1., IV, No. 5573, 195 (1967). Parmley, T. H., and Seeds, A. E., Fetal skin permeability to isotopic water in early pregnancy, Amer. ]. Obstet. Gynecol., 108, ]28 (1970). Scheuplein, R. J., Molecular structure and diffusional processes across intact epider- mis, Final Comprehensive Rep. No. 7, Springfield, U.S. Dept. of Commerce, 1966. Wang, J. H., Self-diffusion and structure of liquid water. I. Measurements of self- diffusion of liquid water with deuterium as a chaser, 1. Amer. Che•n. Soc., 73, 510 (1951).
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