92 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS Society of Cosmetic Chemists Medal Award to Dr. Martin M. Rieger The Society of Cosmetic Chemists presented its 1974 Medal A•vard to Dr. Martin M. Riegel Associate Director of Long-Term Development in the Personal Products Division of Warner-Lambert Company, Morris Plains, N.J. The Medal A•vard, the Society's highest honor, •vas presented to Dr. Rieger in recognition of the many contributions he has made over the years to the cosmetic and toiletries industry and to the Society of Cosmetic Chem- ists organization in particular. The formal presentation •vas made at the December 2nd luncheon during the Socie•'s Annual Scientific Meeting by Dr. Hyman Henkin, 1974 SCC President, and Mr. Charles Fox, a long-time colleague of Dr. Rieger, acted as Eulogist. ß :.• .• :•.•}, • •'•'• '-':-::. •. •'•'•"'•:'-: •-t .'- "::'•-:-•? ...,•'::"- :v-, •- * ß . .... .•C• ' •':• •'?" .:' ::': .•Z ...... k:': ' •: . ' •. •:.•.: '- •'::: ' -:-' : •.• :.-....g•½:.L.:..:.. • •a •- k:. M-- .... .:• "'w -• -..:-..-." ..' -•-•.•.4½ •: ..... - •' -----• ..4' .'-:-a** . s•.:%.,•. ,.( .:• , : ß p.,. .-.. ...2... •: * . ½•.....::..:'.•..:•::• ..... : .... .::.. .... 5::•,-,.,:., .... .?.• .•½: , .:•¾::..:,:c:•,... ,: •,. •%,,• ....:..t,,:, ..•:. ?•:':*::•* ..,--:•...--*'*-:'• -*• -• • ..... :.• ß .'•:-a..: ½-- •:•½• :. ,,?..--.•-•::• • • ,•* . • *'•. ,. ,•,•k:•{ '*. •.... f&a:--..'•' ..** .. • ß ...a ,. .% • ..: .... , ....... ...... ............... **...:,. •*':•½2•.. ::.• ..... ß ...... . ... :.. ß ......... .:. .... -•: • •-•.... :4.• -E . --, s :::-•4:.:•?•.. :- . '• :*•' -:.:-•.. ::-:&' :•s ..... : : •:: - :&• m•.?.: ....• . :. --..:..•..•?•%: .-•:. -. ,. ... ..-.•.:.---- .:.. .y..•c .. • .:: . .... . . -- ..:g ..,. ].**.- .-. .. * .,a•. •-,•-...... -• ß .., ....,.,.:..:.:. ..:• ß .-. •.:::•..-' . :y' ..... ...:. '.•, ---".-. :.•., •: , ... :.. ? .... . ':.:' ...:... : " 7 '- ..•.,..:• :•' ..•-' " :--,• • •] :•-: ' ': • • ¾?..,..:'c-: •:::.:•..•. :/ ,"t, ...• : a,? • '•::'. ....:'.e'.. *.. ., '" -'•K • ' . ,. .•q .,: ,. • •. -.. •-.,. ?.,, , .-• .•'" .% .?* •'... , ....... ,,: ..,:-,". : %... ... .. '• .. •:.:.]..:.,:.. . .. Le•t to right: Medal Award Chairman Lester I. Conrad, Society President Hyman Henkin, Medalist Martin M. Bieger, and Eulogist Charles Fox

I. Soc. Cosmet. Chem., 26, 93-104 (February 1975) Resorptionsm/Jglichkeiten der Haut F. MEYER':' und J. ZIEGENMEYER':' Nach einem Vortrag anliifilich der Tagung der Gesellschafl Deutscher Kosmetik-Chemiker e. V. in Baden-Baden, 13.--15.3. 1974 Synopsis--The Absorption Potential of Skin. -- PENETRANTS are defined as materials which can transport actives into the CORIUM OF SKIN and act as ACCELERATORS OF ABSORPTION. Transport into the corium appears to occur i n t o t o without any ip- preciable selectivity. Within the epidermis the penetrant evidently loses its efficacy, and transport becomes increasingly dependent on the active. The velocity of PERCUTANEOUS ABSORPTION can be exceedingly high. Thus the presence of DYES in the corium or the ACTION OF LIDOCAINE can be demonstrated already 15 minutes after EXTERNAL APPLICATION. Differences in absorption between LABORATORY ANIMALS and MAN can be expected and are related, in part, to the thickness of the epidermis and the density of hair. Finally, it has been known for some time that DISEASED, DAMAGED, or AGED SKIN has an altered ability to absorb foreign materials. The behavior i n the skin will, of course, have a major influence on CAPILLARY ABSORPTION. Depot action in the epithelium must also be considered since resorption can continue even after termination of external contact. This appears particularly important in the case of COSMETICS since, in principle, ACCELERATION OF PENETRATION is possible. Sometimes, this is desirable for an INTENTIONAL "DEEP" ACTION. Often, it will however be less desirable because the unavoidable absorption cannot be controlled. It is not certain whether and to what degree penerrants or the subsequent interference with penetration can be used to generate meaningful effects in deeper layers of the ikin. In principle it appears at least theoretically possible to control the depth of penetration. On the other hand, it is frequently metho- dologically extremely difficult to describe the required parameters quantitatively. Overall, the TECHNOLOGICAL EFFORTS OF COSMETIC RESEARCH should be s u p p o r t e d more than previously by ANIMAL EXPERIMENTATION. This will permit an early deter- mination whether percutaneous absorption of materials from cosmetic preparations can occur or can be precluded. Auch eine intakte Haut schiitzt den Organismus nicht vollstiindig gegen iiufgere chernische Einfiiisse. Aus der Toxikologie ist z. B. die percutane Auf- hahroe yon Alkylphosphaten, Phenolen, Salicylsiiurederivaten und Hexa- chlorophen seit langem bekannt. •ufgerlich applizierte Substanzen kiSnnen so- reit die Haut durchdringen und auf diesera Wege in den allgemeinen Kreis- lauf gelangen. Sie ist eben doch durchliissig fiir eine in ihrer Gesamtheit noch ':' Prof. Dr. med. F. Meyer, Direktor des Instituts for Pharmakologie und Toxikologie der Technischen Universitiit Carolo-Wilhelrnina, D-33 Braunschweig, Pockelsstr. 14 Dr. I. Ziegenrneyer, ebenda. 93