619 CENTELLA ASIATICA EXTRACTS IN SKIN REPAIR PRODUCTS Table IV Results of the Cosmetic Qualities and Efficacy Evaluation Aspect evaluated Number (% of mothers or fathers) Strongly agree Somewhat agree Somewhat disagree Strongly disagree Promoted skin repair 9 (81.8) 1 (9.1) 1 (9.1) 0 (0.0) Alleviated reddening 9 (81.8) 1 (9.1) 1 (9.1) 0 (0.0) Repaired rubbing or friction (chafing) zones 10 (90.9) 0 (0.0) 1 (9.1) 0 (0.0) The product is rapidly absorbed The product does not leave a sg415cky sensag415on on the skin The product does not leave an oily sensag415on on the skin The product does not stain clothing Figure 3. Results of the cosmetic qualities evaluation in the efficacy and acceptability study of Blastoactiva™ in pediatric population. Figure 4. Results of the cosmetic efficacy evaluation in the efficacy and acceptability study of Blastoactiva™ in pediatric population. Percentage (%) of parents satiied

620 JOURNAL OF COSMETIC SCIENCE CONCLUSION Blastoactiva™ cream, based on the combination of the active extracts of C asiatica, asiaticoside and asiatic acid, has been the subject of different experimental and human studies. These studies confirm its beneficial anti-irritant effect, skin barrier function repair and epidermal cell renewal enhancing action, as well as great acceptability referred to its cosmetic characteristics with no allergenic or phototoxic potential. Repair of the skin damaged by dryness (xerosis), superficial acne scarring, or superficial aggression produced by physical agents such as cold, wind, pollution, solar exposure, and diaper rash, or after cosmetic/nonsurgical treatments (laser, peeling, depilation and epilation, tattoos, and phototherapy sessions) are some clinical scenarios where the use of Blastoactiva™ would be especially indicated. ACKNOWLEDGMENTS We thank Marta Pulido, MD, for editorial assistance. RESEARCH ETHICS Any aspect of the work covered in this manuscript that has involved human patients has been conducted with the ethical approval of all relevant bodies. REFERENCES (1) A. Guerra-Tapia, E. Serra-Baldrich, L. Prieto Cabezas, E. González-Guerra, and J. L. López-Estebaranz, Diagnosis and treatment of sensitive skin syndrome: an algorithm for clinical practice, Actas Dermosifiliogr., 10, 800–808 (2019). (2) A. Pons-Guiraud, Sensitive skin: a complex and multifactorial syndrome, J. Cosmet. Dermatol., 3, 45–48 (2004). Promoted skin repair Alleviated reddening Repaired rubbing or friction (chafing) zones Figure 5. Results of the cosmetic efficacy evaluation in the efficacy and acceptability study of Blastoactiva™ in pediatric population. Percentage ( of parent s s