338 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS

LANOLIN DERIVATIVES FOR PRESSURIZED FORMULATIONS 330 (1) After 1 hour at 20 ø C Propellant 12 (dichlorodifiuoromethane) The solubility of the lanolin products is poor in Propellant 12, with the exception of liquid lanolin I.S.O. (vi) and liquid lanolin "L.I.N." (viii). The addition of D/IS effects complete, or nearly complete, solubility of all products, with the exception of anhydrous lanolin, B.P. (i). Propellant 11 (trichlorofiuoromethane) The solubility of the lanolin products is good or excellent, with the excep- tion of water soluble lanolin "75" (ix) and water soluble wool alcohols "20" (x). The addition of the IMS effects virtually complete solubility of products (ix) and (x). Propellant 114 (dichlorotetrafiuoroethane) The solubility of the !anolin products in Propellant 114 is negligible. The addition of D/IS effects complete, or nearly complete, solubility of all products except anhydrous lanolin, B.P. (i), and water soluble lanolin "75" (ix). Propdlants 11/12 mixture The solubility of the lano!in products is good or excellent, with the exception of alcohol soluble lanolin (iv), water soluble !artolin "75" (ix), and water soluble wool alcohols "20" (x). The addition of the D/IS effects virtually complete solubility of the first two products, but has no effect on the last named. The addition of the isopropanol does not have so marked an effect, although it improves the solubility of the alcohol soluble lanolin (iv). (2) Storage for 6 weeks at 20 ø C In general there have been only minor changes in solubility during the test period. The exceptions are alcohol soluble lano!in (iv) in Propellant 11 (B), and water soluble lanolin "75" (ix) in propellants 11/12/IMS (H) where partial precipitation has occurred, accompanied by agglomeration in the latter. There has also been a tendency for some of the other precipitates to agglomerate which could be a potential cause of valve blockage. (3) Storage for 6 weeks at 0 ø C There is a slight decrease in solubility of some of the products, and also a tendency for some of the precipitates to agglomerate, but this phenomenon is not restricted to those products which form agglomerates during storage at 20 ø C. (4) Storage for 8 weeks at 0 ø C, followed by storage for 24 hours at 20 ø C In general the solubilities are similar to those noted after storage for