502 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS they are Schedule 4B poisons subject to the Drugs, Prevention of Misuse, Act, 1964). One wonders whether there are errors falling in other areas of know- ledge, of which the reader has not sufficient first hand experience to know at a glance whether the statement is true or false. Although the two mistakes quoted above are rather trivial in them- selves, they are unfortunate insofar that this is the type of book to be read by politicians, journalists and others inter- ested in the pharmaceutical industry. These worthy gentlemen are guilty of enough claptrap when discoursing on scientific matters without actually feed- ing them erroneous information - particularly on the currently highly emotional subjects of drug toxicity and abuse. However, in many ways the authors have done a good job. They consider contributions to drug research from academic and governmental laboratories as well as from the industry, and generally present a well balanced picture. They are not slow to criticise the indus- try and they pose provocative questions regarding the dichotomy of academic and industrial research, giving con- sideration to nationalising research instead of the industry, extending the time limit on provisional patent protec- tion, and regarding the need for more clinical pharmacologists and clinical trial centres, etc. Particularly forthright is their criticism of companies xvho purport to be the inventor of a drug when in fact all they have done is to secure a licence from a foreign inventor. Although the prose is always elegant and well constructed, the general style is very readable, not without a little wit, and sometimes informal to the point of chattiness. These volumes should be recom- mended reading for all students inter- ested in entering the pharmaceutical industry, particularly the R & D sector, and it will be of considerable use to scientific historians. The authors are probably a little optimistic in hoping to extend their readership to the layman since a fair knowledge of chemistry and biology is necessary for a full under- standing of the text, although the practising scientist who requires a little general reading will find it always interesting and sometimes fascinating. Volume 2 includes a useful glossary of medical and pharmacological terms, an extensive bibliography and a classi- fied index. There are at least three minor spelling mistakes and there is some confusion in p. 185 regarding the numbering of diagrams of structural formulae. Also Table 8.1 in p. 50 could give the reader the impression that Probenecid gives relief from gout by promoting uric acid resorption in the kidney tubule whereas in fact the opposite is the case. B. CooK. THERMOMETRIC TITRIMETRY. L. S. Bark and S. M. Bark. Pp. ix + 126 + Ill. (1969). Pergamon Press, O•ford. •2.25 (45s). Most analytical titrations involve an endo- or exothermic reaction but in the past relatively little use has been made of this fact. Recently there has been more interest and it is now clear that thermometric titrations can play a useful role in routine and research analysis. This volume is one of the few publications where information on this subject has been collected. The book covers the history, the basic principles and the equipment required. The many applications include neutralization titra- tions (including mixtures of strong and

BOOK REVIEWS 503 weak acids and bases), Redox systems, precipitation reactions, •netal cmnplexes and non-aqueous titrations. One main advantage of the technique is that a variety of analytical procedures can be performed rapidly with one piece of apparatus and this makes it attractive for industrial applications, e.g. for the metallurgical, petrochemical, pharma- ceutical, soap and detergent industries. Thermometric titrations have great potential, probably more than any other method, for rapid on-line analysis which could mean that further progress is likely to occur in the near future. This volume will be of interest to most analysts and it is a useful and up to date introduction to the subject. Note: In Chapter 9 "Industrial Analysis" the authors have confused anionic and cationic detergents. In pages 100 and 101 the reader should substitute anionic for cationic and vice versa. Mrs. D. M. GABreEL PHYSICAL PROPERTIES OF STEROID CONJUGATES. S. Bern- stein, J. P. Dusza and J. P. Joseph. Pp. xi + 212. (1968). Springer-Verlag, Berlin, Heidelberg, New York. DM 48 $12. This is a useful handbook for those who require a ready source of reference to the physical constants of steroid conjugates and their derivatives. The authors mention that some of the compounds have been arbitrarily selec- ted, but the primary emphasis has been directed towards 'useful over-all com- pleteness'. The catalogue is arranged according to the empirical formula of the parent steroid and the references to the various data supplied are given in a separate list at the end of the book. In some cases several references for similar physical constants are given in an effort to detail all relevant characterization data. M. A. CooK•. DISPOSAL OF PROCESS WASTES. M. Wulfinghoff. Pp. vii + 240 + Ill. (1•68). Che•ical Publishing Co., New York. $12.50. Air and river pollution is a •najor problem in practically every country of the world. England is certainly no ex- ception on this score and, as one is well aware, a great deal of work is carried out with a view to improving the situation. The volume being reviewed is the result of a symposium, the Achema meeting in Frankfurt in 1.064 and whilst it not surprisingly has a bias towards the problems of German industry, is of general interest. Certainly works engin- eers seeking to improve the waste and effluent situations of their own works would be interested in reading this volume though it is likely to be of less interest to cosmetic chemists themselves. Examples of treatment are taken from a wide range of industries and cover treatment of gases and liquid waste. Some emphasis is also given to recovery and utilisation of materials in the process of treatment. At a cost of approx. •5, this is likely to have a limited appeal to readers of this Journal, though they may be interested in recommending it t• their engineering staffs. C. PUGH. SCHNELLMETHODEN UND AUTO- MATISIERUNG IN DER ANALYSE- CHROMATOGRAPHISCHE METHO- DEN. Dechema-Monographien Nr. 1102- 1124. 62. Pp. 313 q- Ill. (1968). Verlag Chemie, Weinheim. DM 56.25. This volume is the latest in the series of monographs from Dechema. Each volume deals with different sub-