COSMETIC TESTING ON MAN 349 Literatur 1. Empfehlungen ftir Hautvertr•iglichkeitsprtifungen von K•Srperpflegemitteln (Kosmetische Erzeugnisse). Gemeinschat•sarbeiten der DGF: 54. Mitteilung Fette, Seifen, Anstrichmittel 73, 467--469 (1971). 2. Shelanski, H. A. and Shelanski, M. V., A new technique of human patch tests, Proc. Sci. Sect. Toilet Goods Ass. 19, 46--49 (1953).

I. Soc. Cosmet. Chem., 27, 351-363 (August 1976) A Stereomicroscopic Method For Determination Of Moisturizing Efficacy In Humans The DEREK R. HIGHLEY, Ph.D.,* VERA O. SAVOYKA, B. Sc.,t JOHN J. O'NEILL, Ph.D.,* and JOHN B. WARD, Ph.D.** Presented, May 30, 1976, SCC Annual Seminar, St. Louis, Mo. Synopsis: A Stereomicroscopic Test for Moisturizing Efficacy has been developed, which is based upon the ability of moisturizers to prevent or alleviate soap-induced dry skin using the back of the hand as a substrate. The method is founded on objective definitions of the terms "dry skin" and "moisturizer." These definitions do not apply any particular etiology of the condition, nor do they imply any particular mechanism of efficacy in treatment. One advantage of this procedure is that it permits comparative efficacy measurements on moisturizing preparations regardless of their form or water content. Another is, that by means of this test using panels of small size, information is generated, which could otherwise be obtained only through clinical testing on large populations. A numerical grading system for relative skin dryness has been developed by means of which a numerical measure of moisturizing efficacy is obtained. Computerized statistical analysis of the data is performed when two materials are compared for moisturizing efficacy. INTRODUCTION The influence of moisturizing agents on the status of stratum corneum water has been the subject of numerous publications. Water vapor transmission *The Gillette Co., Personal Care Division, Gillette Park, Boston, MA 02106. •20 West 64th St., New York, N.Y. 10023. *Avon Products Inc., Suffern, N.Y. 10901. **Cyanamid Consumer Research Center, Clifton, N.J. 07015. 351