WATER RESISTANCE OF SUNSCREENS 87 80 • 20 0 80 60- 40- 20- oo +++ OMC •-+++ cq- r W/O EMULSION -- BENZOPHENONE-3 CONTROL [2] PP-2 [73 TRICONTANYL PVP COPOLYMER - Significant differences from control, * = p_0.10, ** = p_0.05 - Significantly differences between treatments amongst two emulsion types, +++ = p_0.01 Figure 2. Amount of sunscreens retained from emulsions inside stratum coeneum in water-resistance measurements using pig skin (n = 4).

88 JOURNAL OF COSMETIC SCIENCE Table VI Sunscreen Distribution From O/W and W/O Emulsions in Water-Resistance Measurements (n = 4) Benzophenone-3 (% Applied dose _+ SEM) Penetrated Retained (receptor + Total Washes (inside SC) viable skin) Recovery O/W emMsio. Control PP-2 Tricontanyl PVP copolymer W/O emulsion Control PP-2 Tricontanyl PVP copolymer O/W emuhion Control PP-2 Tricontanyl PVP copolymer W/O emulsion Control PP-2 Tricontanyl PVP copolymer 45.88 _+ 2.54 42.2 _+ 2 6.28 + 0.48 94.36 46.76 + 4.77 38.46 + 3.16 5.25 + 0.64 90.47 33.86 -+ 5.99* 58.15 + 5.58** 4.71 + 0.73 96.72 50.8 _+ 3.68 27.34 + 2.61 4.92 -+ 0.76 83.06 56.87 + 2.13 29.93 + 1.33 3.91 + 0.08 90.71 57.49 -+ 3.3 30.44 _+ 3.69 3.25 -+ 0.45 91.18 OMC (% Applied dose _+ SEM) 47.39 -+ 2.77 48.38 + 2.28 3.69 -+ 0.55 99.46 50.09 + 5.31 45.35 + 3.73 3.33 ñ 0.58 98.77 34.23 _+ 6.58* 64.54 _+ 6.39* 2.99 -+ 0.56 101.76 55.62 + 4.02 31.88 _+ 3.27 2.14 _+ 0.52 89.64 58.29 _+ 2.91 32.43 _+ 1.36 1.84 + 0.05 92.56 62.67 _+ 3.63 33.14 _+ 4.12 2.04 _+ 0.47 97.85 Significantly different from control: * p -- 0.10 ** p -- 0.05. Table VII Amount of Sunscreens in the First Two Strips as Percent of Total Retained Inside SC From O/W and W/O Emulsions (n = 4) Benzophenone-3 OMC (+SEM) (+SEM) O/W emulsion Control 47.82 _+ 3.71 48.02 _+ 3.54 PP-2 46.13 _+ 1.5 46.3 + 1.42 Tricontanyl PVP copolymer 62.02 + 1.93'* 61.36 _+ 1.85'* W/O emulsion Control 61 + 4.44? 58.55 -+ 4.89 PP-2 57.8 _+ 3.62't" • 55.92 -+ 3.27•'? Tricontanyl PVP copolymer 67.45 _+ 2.09 61.57 + 2.56 Significant differences from control: ** = p -- 0.05. Significant differences between treatments among two emulsion types: •' = p 0.10 ?'• = p 0.05.