190 JOURNAL OF COSMETIC SCIENCE or suspended in appropriate cream and lotion vehicles. In these formulations a slow release of octyl methoxycinnamate from the complex takes place, resulting in a long- lasting protection of the skin (Lipo Chemicals Inc.). Stability of emulsions. In a simple three-component system of paraffin oil, water, and [3-cyclodextrin, stable emulsions are formed. The formed emulsions are stable under various storage conditions. However, the origin of this stabilization effect can not be given at present (38). The apparent viscosity of these emulsions strongly depends on the cyclodextrin concentration. The stabilization effect of [3-cyclodextrin on emulsions formed from triglyceride and water has also been reported (39). CONCLUSION Cyclodextrins are already used in cosmetic products. They offer many advantages. For example, the discussed effects of the stabilization of substances, reducing their vapor pressure, and increasing their solubility cannot be easily achieved with other formulation techniques. Due to further decreases in their prices, more applications will become possible in the near future. The use of textiles with permanently fixed cyclodextrins offers new applications for cosmetic formulations (14). These textiles may act as depots for cosmetic compounds. They will be released from the cyclodextrins only in contact with the skin. ACKNOWLEDGMENT Financial support within the scope of the project "Textile" from the Ministerium ftir Schule, Wissenschaft und Forschung of Nordrhein-Westfalen is gratefully acknowl- edged. REFERENCES (1) (2) (3) (4) (5) (6) (7) (8) (9) (10) A. Villiers, Sur la transformation de la fdcule en dextrine par le ferment butyrique, Cornpt. Rend. Acad. Sd. Paris, 112, 435--437 (189l). F. Schardinger, Ober thermophile Bakterien aus verschiedenen Speisen und Milch, sowie tiber einige Umsetzungsprodukte derselben in kohlehydrathaltigen Niihrl/3sungen, darunter krystallisierte Poly- saccharide (Dextrine) aus Stiirke, Z, Untermch. Nahrungsm. Genussm., 6, 865-880 (1903). K. Freudenberg, G. Blomqvist, and L. Ewald, Hydrolyse und Acetolyse der Stiirke und der Schard- inger-Dextrine, Chem. Ber., 69, 1258-1266 (1936). K. Freudenberg and F. Cramer, Die Konstitution der Schardinger-Dextrine ix, [3 and •, Z. Naturfor- schg., B3, 464 (1948). W. Borchert, R/3ntgenographische Untersuchungen an Schardinger-Dextrinen, Z. Naturforschg., B3, 464-465 (1948). .. F. Cramer, Uber EinschluBverbindungen, I. Mitteil: Additionsverbindungen der Cycloamylosen, Chem. Ber. 84, 851-854 (1951). W. Saenger, Cyclodextrin inclusion compounds in science and industry, Angew. Chem. Int. Ed., 19, 334-352 (1980). J. Szejtli (Ed.), Proceedings of the First International Symposium on Cyclodextrins (D. Reidel, Dordrecht, 1982). J. Szejtli, Cyclodextrins and Their Inclusion Complexes (Akademiai Kiado, Budapest, 1982). K.-H. Fr/3mming and J. Szejtli, Cyclodextrins in Pharmacy (Kluwer, Dordrecht, 1994).
C¾CLODEXTRINS 191 (21) (22) (23) (24) (25) (26) (27) (28) (29) (3o) (31) (11) T. Loftsson, Cyclodextrins in Pharmaceutical FormMations (Department of Pharmacy, University of Ice- land, 1998). (12) J. Szejtli, Cyclodextrin Technology (Kluwer, Dordrecht, 1988). (13) D. Duch•ne (Ed.), New Trends in Cyclodextrins and Derivatives (Editions de Sant6, Paris, 1991). (14) H.-J. Buschmann, D. Knittel, and E. Schollmeyer, New textile applications of cyclodextrins, J. Incluion Phenom., 40, 169-172 (2001). (15) J. Szejtli, Cyclodextrins in food, cosmetics and toiletries, Starch, 34, 379-385 (1982). (16) H. Yokota, Application of cyclodextrin to cosmetic products and its problems, FragraneJ., 11, 84-89 (1983). (17) H. Hashimoto, Application of cyclodextrins to food, toiletties and other products in Japan, Proceeding• of the Fourth International Symposium on Cyc/odextrim, O. Huber and J. Szejtli, Eds. (Kluwer, Dordrecht, 1988), pp. 533-543. (18) M.E. Brewster, in New Trend• in Cyclodextrins and Derivatives, D. Duchane, Ed. (Editions de Sant•, Paris, 1991), p. 313. 09) Erste Verordnung zur •nderung zusatzsoff•echtlicher Vorschriften vom 13.11.2000 (BGB1, I S. 1520), Anlage 4, Tell B. (20) D. Duchene, D. Wouessidjewe, and M.-C. Poelman, "Derreal Uses of Cydodextrins and Derivatives," in New Trends in Cyclodextrins and Derivatives, D. Duch•ne, Ed. (Editions de Sant6, Paris, 199l), pp. 449-48 l. P. K/Shler, R.-D. Petersen, and S. Botcherr, Stabilization of tea tree oil, S(SFWJ., 125, 7, 10-12 (1999). V. Tsomi, Cosmetic skin-lightening composition based on a hydroquinone/2,6-dimethyl-[3- cyclodextrin complex, WO 9 l/18589 (1991). S. Hatae and K. Nakashima, Whitening cosmetic, EP 0241572 A1 (1987). M. Granger, M. Dupont, and H. Ledon, Clathrates of peroxyacids, their preparation and their uses. US 5382571 (1995). J. Kock, Storage of stable, powdered detergent and cleaning agent containing perfume, DE 30 20 269 (1981). D. R. Bacon and T. Trinh, Detergent compositions containing enduring perfume, US 5500154 (1996). M. Kubota and R. Komaki, Long-lasting perfume compositions containing (-)muscone,Jpn. Kokai, Tokkyo KohoJP 07,324,196 (1995). H. Matsuda, K. Ito, A. Taki, and O. Uejima, Cosmetic composition containing inclusion product with hydroxyalkylated cyclodextrin, US 5447920 (1995). G. Decknet and C. Sang, Cosmetic compositions, WO 98/56345 (1998). J. Pitha, Water soluble forms retinoids, US 4371673 (1983). T. Wimmer, M. Regiert, and J.p. Moldenhauer, Stabilization of retinol with •-cyclodextrin, Proceed- ings of the 9th International Symposium on Cyc/odextrins, J. J. Torres Labandelta and J. L. Vila Jato, Eds. (Kluwer, Dordrecht, 1999), pp. 407-410. (32) 1. Matsuura, Y. Kimura, Y. Sakai, and N. Nakatsuji, Glutathione-cyclodextrin inclusion complex for cosmetic compositions, EP 0442420A1 (1991). (33) S. Kubo and F. Nakamura, Waving lotion for cold waving, US 4548811 (1985). (34) P. C. Schmidt, S. Stamm, B. Hempel, and D. Berndt, Kosmetische und pharmazeutische Mittel auf Basis eines Kamillenextraktes, DE 19746284 A1 (1999). (35) G.J. Guskey, D. R. Bacon, P.S. Junneja, C. B. Motley, and G. P. Rizzi, Deodorant compositions containing cyclodextrin odor controlling agents, US 6123932 (2000). (36) J. Szejtli and E. Bolla, Stabilisierung fett/Sslicher Vitamine mir beta-Cyclodextrin, Starch, 32,386-391 (1980). (37) J. Pitha, Enhanced water solubility of Vitamins A, D, E, and K by substituted cycloamyloses, Li• Sci., 29, 307-311 (1981). (38) S. Laurent, M. Serpelloni, and D. Pioch, A study of 13-cyclodextrin-stabilized paraffin oil/water emulsions. J, Cosmet. Sci., 50, 15-22 (1999). (39) K. Shimada, K. Kawano, J. Ishii, and T. Nakamura, Structure of inclusion complexes of cyclodextrins with triglyceride at vegetable oil/water interface,.]. Food Sci., 57, 655-656 (1992).
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