MONITORING OF UV FILTERS BY HPLC 117 MA, MBC, BZ-3, BZ-8, BMDM, OC, ED-PABA, EMC, PABA, IMC, DBT, PBS, and TDS, and THF was used for EHT and MBBT. The recoveries from the spiked UV fi lters were 94.90–116.54%, depending on the matrixes used. The method was applied to 23 commercial sunscreen samples to determine the contents of 16 UV fi lters, which showed acceptable levels compared with label claims and maximum authorized concentrations. Con- sequently, the method provides assessable and effi cient determination of UV fi lters, in- cluding DBT, TDS, and MBBT, that are recently registered in the EU or USA. ACKNOWLEDGMENT This study was supported by a grant (09101 KFDA 251) from the Korea Food & Drug Administration. REFERENCES (1) C. Tuchinda, H. W. Lim, U. Osterwalder, and A. Rougier, Dermatol. Clin., 24, 105–117 (2006). (2) E. C. De Fabo, F. P. Noonan, T. Fears, and G. Merlino, Cancer Res., 64, 6372–6376 (2004). (3) P. Kullavanijaya and H. W. Lim, J. Am. Acad. Dermatol., 52, 937–958 (2005). (4) D. Sehedic, A. Hardy-Boismartel, C. Couteau, and L. J. Coiffard, Arch. Dermatol. Res., 301, 603–608 (2009). (5) A. Fourtanier, D. Moyal, and S. Seite, Photodermatol. Photoimmunol. Photomed., 24, 164–174 (2008). (6) S. Scalia, R. Tursilli, and V. lannuccelli, J. Pharm. Biomed. Anal., 44, 29–34 (2007). (7) L. R. Gaspar and P. M. Maia Compos, Int. J. Pharm., 307, 123–128 (2006). (8) P. P. Agin, K. Ruble, S. J. Hermansky, and T. J. McCarthy, Photodermatol. Photoimmunol. Photomed., 24, 211–217 (2008). (9) S. Durrer, C. Ehnes, M. Fuetsch, K. Maerkel, M. Schlumpf, and W. Lichtensteiger, Environ. Health Perspect., 115(Suppl. 1), 42–50 (2007). (10) J. Ashby, H. Tinwell, J. Plautz, K. Twomey, and P. A. Lefevre, Regul. Toxicol. Pharmacol., 34, 287–291 (2001). (11) A. Zenker, H. Schmutz, and K. Fent, J. Chromatogr. A, 1202, 64–74 (2008). (12) L. Dimosthenis, L. Giokas, A. Salvador, and A. Chisvert, Trends Anal. Chem., 26, 360–374 (2007). (13) D. De Orsi, G. Giannini, L. Gagliardi, R. Porrà, S. Berri, A. Bolasco, I. Carpani, and D. Tonelli, Chro- matographia, 64, 509–515 (2006). (14) D. J. Schakel, D. Kalsbeek, and K. Boer, J. Chromatogr. A, 1049, 127–130 (2004). (15) A. Chisvert and A. Salvador, J. Chromatogr. A, 977, 277–280 (2002). (16) A. Chisvert, M. C. Pascual-Marti, and A. Salvador, Fresenius’ J. Anal. Chem., 369, 638–641 (2001). (17) C. Couteau, A. Faure, J. Fortin, E. Paparis, and L. J. Coiffard, J. Pharm. Biomed. Anal., 44, 270–273 (2007). (18) H. R. Buser, M. D. Muller, M. E. Balmer, T. Poiger, and I. J. Buerge, Environ. Sci. Technol., 39, 3013– 3019 (2005). (19) E. Chatelain and B. Gabard, Photochem. Photobiol., 74, 401–406 (2001).