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Appendix 1 Overview of the 217 proteins identifi ed and quantifi ed in at least 75% of the samples. Proteins (but not protein groups) are listed with the obtained sequence coverage, number of peptides identifi ed for that protein, number of unique peptides identifi ed per protein. Additionally, some proteins can be linekd to the proteomic procedure used and are indicated with an ‘x’ as artefact. Protein Description Sequence Coverage (%) #Peptides #Unique peptides Artefact Keratin-associated protein 2-3 99 41 28 Keratin 36 97 44 4 Keratin type I cytoskeletal 39 96 27 3 Keratin-associated protein 3-1 96 26 2 Keratin-associated protein 4-2 96 26 2 Keratin 81 93 105 1 Keratin 83 93 100 5 Keratin 85 92 63 15 Keratin 85 91 96 8 Keratin 33B 90 82 16 Keratin 32 90 57 12 Keratin-associated protein 2-4 90 43 5 Keratin 33A 88 68 17 Keratin-associated protein 9-9 87 41 2 Keratin 31 85 88 1 Keratin 38 84 37 5 Histone H4 L 84 22 20 Keratin-associated protein 9-8 83 55 1 Keratin-associated protein 4-6 83 25 1 Keratin-associated protein 11-1 82 23 13 Keratin-associated protein 1-1 81 35 4 Keratin-associated protein 9-6 80 31 1 Keratin-associated protein 13-2 78 15 3 Keratin-associated protein 9-3 75 39 1 Trypsin I (Fragment) 75 15 7 x Keratin associated protein 4-6 73 29 12 cDNA FLJ25625 fi s clone STM02974 72 19 5 PRSS1 protein 71 15 6 x Keratin-associated protein 4-3 70 19 2 Trypsin-1 (Fragment) 69 22 13 x Keratin-associated protein 9-4 68 33 1 Protease serine 1 (Fragment) 68 7 6 x Trypsin-1 67 12 3 x Trypsin-6 66 16 1 x Histone H4 H 62 18 6 Protease serine 1 (Fragment) 62 6 1 x Trypsin-2 62 6 1 x Histone H4 A 57 16 3 V-set and immunoglobulin domain-containing protein 8 57 16 3 Protease serine 1 (Fragment) 56 12 2 x Anionic trypsinogen 56 16 1 x Protein S100-A3 55 19 1 PRSS2 protein (Fragment) 47 6 6 x Protease serine 2 preproprotein 47 6 6 x Protease serine 2 43 9 7 x Keratin-associated protein 3-3 37 22 2 Transcription factor 4 36 4 4 HAIR SHAPE PROTEOMICS 263