SUBMISSION DEADLINE : March 31st, 2021 Sponsorship Information Be a part of the 2021 Sunscreen Symposium. Contact Peter Toth - or Carol Holmes for your opportunity to be recognized! Predicting the Future: Sun Care Trends in an Uncertain Regulatory Environment Attendee or Exhibitor Registration: sunscreensymposium21 Hotels reservations: Click here or call (407) 939-4686 Don’t forget to Register for the Golf event & GALA! See you there! (GALA event included in full reg, Golf is seperate.)
Insights in Human Hair Curvature by Proteome Analysis of Two Distinct Hair Shapes EVELYNE MAES, FRASER BELL, CHARLES HEFER, ANCY THOMAS, DUANE HARLAND, ALASDAIR NOBLE, JEFFREY PLOWMAN, STEFAN CLERENS, and ANITA GROSVENOR , Beyond Food, AgResearch Ltd., Lincoln 7674, New Zealand (E.M., A.T., D.H., J.P., S.C., A.G.), Unilever R&D, Port Sunlight, Bebington, Wirral CH63 3JW (F.B.), United Kingdom , Knowledge and Analytics, AgResearch Ltd., Lincoln 7674, New Zealand (C.H., A.N.), Biomolecular Interaction Centre, University of Canterbury, Christchurch 8041, New Zealand (S.C.), Riddet Institute, Massey University, Palmerston North 4474, New Zealand (S.C.) Accepted for publication January 6, 2021. Synopsis Scalp hair is a universal human characteristic, and a wide range of hair shape and color variations exists. Although differences in human scalp hair shape are visually apparent, the underpinning molecular insights are yet to be fully explored. This work reports the determination of differences at the protein level between two distinct groups of hair shape: very straight samples versus very curly hair samples. An in-depth high- resolution liquid-chromatography mass spectrometry proteome analysis study was performed on hair samples from 50 individuals (pooled in 10 × 5 samples) with very curly hair and 50 subjects with very straight hair (pooled in 10 × 5 samples) to decipher differences between the two experimental groups at the protein level. Our results demonstrate that a distinction between the two experimental groups (very straight vs. very curly) can be made based on their overall protein profi les in a multivariate analysis approach. Further investigation of the protein expression levels between these two groups pinpointed 13 unique proteins which were found to be signifi cantly different between the two groups, with an adjusted p-value 0.05 and a fold change of more than two. Although differences between the very curly and the very straight hair sample groups could be identifi ed, linkage between population differences and curl phenotype is currently unknown and requires further investigation. INT RODUCTION Hum an scalp hair is an important component of personal identity, and the perception of hair quality measured by numerous visual appearance and tactile aspects is of crucial importance to consumers. Individual hair-care needs and aspirations are diverse, and Address all correspondence to Anita Grosvenor at 249 J. Cosmet. Sci., 72, 249–267 (May/June 2021)
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