122 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS Draize had accepted a position as toxicologist at Edgewood Arsenal. He studied the effect of chemical warfare agents on skin and mucous membrane. These investigations remain unpublished. This assignment was the beginning of his specialization in the study of dermal toxicity. He entered the Food and Drug Administration in 1939, and was appointed Chief of the Skin Toxicity Branch in 1947. During the war he con- ducted a number of studies involving products of interest to the Armed Forces. His present duties include development of techniques for derreal and mucous membrane studies, as well as the testing of samples and compounds that are involved in the regulatory work of the Administration. While his duties are by no means confined to testing of cosmetics, he had contributed greatly to the progress of the cosmetic industry. There are few procedures, if indeed there are any, for determining derreal toxic- ity that Dr. Draize and his co-workers have not either developed or refined. His methods and techniques are used daily by workers in many countries. A complete list of publications by Dr. Draize forms the appendix to my remarks. The work represented by these publications covers a broad field indeed. These papers summarize the reasons for the high regard that scientists in the complex field of pharmacology have for Dr. Draize and his group. Dr. Draize is a member of the following professional societies: American Society for Pharmacology and Experimental Therapeutics Society for Experimental Biology and Medicine and the American Association for the Advancement of Science. He is also a member of the honorary professional societies Sigma Xi and Phi Sigma. I have given a few important dates in the life of our Medalist. The account would not be complete without a few more. In 1939, a second son, James John, was born. He is now attending the University of Mary- land. A most important year was 1956, for then the Draizes became grand- parents. They now have two grandchildren. In concluding these remarks, let me say that the Soctv. T¾ can take pride in the excellent choice made by the Medal Award Committee. I am sure that Dr. Draize will treasure the Medal to be awarded to- night. I am also certain that each of us will take satisfaction in the reali- zation that in honoring Dr. Draize we can claim honor to the since such a man accepts our Medal. SCIENTIFIC PAPERS (1) J. H. Draize and A. L. Tatum, "Experimental Thyrotoxicos," ztrch Int. Pharmacol. Therap., 4:3, 237 (1932).

JOHN H. DRAIZE, MAN AND SCIENTIST 123 (2) O. A. Beath, J. H. Draize and H. F. Eppson, "Three Poisonous Vetches," Bulletin 189, University of Wyoming (1932). (3) "Arrow Grass," Chemical and Physiological Considerations," Bulletin 193, University of Wyoming (1933). (4) O. A. Beath, J. H. Draize and H. F. Eppson, "Three Species of Zygadenus (Death Comas)," Bulletin 194, University of Wyoming (1934). (5) O. A. Beath, J. H. Draize, H. F. Eppson, C. S. Gilbert and O. C. McCreary, "Certain Plants Poisonous to Livestock," y./lm. Pharm./lssoc., 23, 94 (1934). (6) J. H. Draize, "Sodium Tetrathionate and Methylene Blue in Cyanide Poisoning," Science, 78, 145 (1933). (7) O. A. Beath, J. H. Draize and C. S. Gilbert, "Plants Poisonous to Livestock," Bulletin 200, University of Wyoming (1934). (8) J. H. Draize and O. A. Beath, "Observations on the Pathology of Blind Staggers and Alkali Disease," y. ,aim. ?et. Med. •lssoc., 86 NS, 39, No. 6, 753 (1935). (9) J. H. Draize, "The Determination of the pH of the Skin," y. Invest. Dermatol., 5, 77 (1942). (10) E. P. Laug and J. H. Draize, "Percutaneous Absorption of Ammonium Hydrogen Sulfide," y. Pharmacol. Expt. Therap., 76, 179 (1942). (11) .[. H. Draize, A. A. Nelson and H. O. Calvery, "Percutaneous Absorption of DDT in Laboratory Animals," Ibid., 82, 159 (1944). (12) J. H. Draize, G. Woodard and H. O. Calvery, "Methods for the Study of Irritation and Toxicity of Substances Applied Topically to Skin and Mucous Membranes," Ibid., 82, 377 (1944). (13) J. H. Draize, O. G. Woodard, A. A. Fitzhugh, R. B. Nelson, P. K. Smith and H. O. Cal- very, "Summary of Toxicological Studies of the Insecticide DDT," Chem. Eng. News, 22, 1503 (1944). (14) J. H. Draize and G. Woodard, "DDT, Its Nature and Applications," Monograph for the Belgian American Foundation (1946). (15) H. O. Calvery, J. H. Draize and E. P. Laug, "The Metabolism and Permeability of Normal Skin," Physiol. Rev., 26, 495 (1946). (16) J. H. Draize, E. Alvarez, M. F. Whitesell, G. Woodard, E. C. Hagan and A. A. Nelson, "Toxicity of Insect Repellants," y. Pharmacol. Expt. Therap., 93, 26 (1948). (17) H. O. Calvery, J. H. Draize and G. Woodard, "Relative Acute Toxicity of Some Or- ganic Compounds Following Oral Administration and Skin Application," Fed. Proc. Soc. Expt. Biology and Med., 2, 842 (1945). (18) J. H. Draize and E. Alvarez, "Discussion of Certain Aspects of Pharmacological Tests on Cosmetics," Proc. Sci. Sec. Toilet Goods/lssoc., No. 12, 12 (1949). (19) .[. H. Draize, E. Alvarez and M. F. Whitesell, "Toxicity and Primary Irritation of Some Chemical Compounds Following Oral Administration and Skin Application," Fed. Proc. Soc. PharmacoL Expt. Therap., 174 (1946). (20) J. H. Draize, "Procedures for the Appraisal of the Toxicity of Chemicals in Foods," Food, Drug and Cosmetic Law •uart., 412 (1949). (21) J. H. Draize, E. Alvarez and M. F. Whitesell, "Percutaneous Toxicity of Thioglyco- lates," Proc. Sci. Sect. Toilet Goods/lssoc., No. 7, 29 (1947). (22) M. V. Freeman, J. H. Draize and E. Alvarez, "Cutaneous Absorption of Phenol," y. Lab. Clin. Med., 38,262 (1951). (23) "Toxicity to Eye Mucosa of Certain Cosmetics Containing Surface Active Agents," Proc. Sci. Sect. Toilet Goods •lssoc., No. 17, 1 (1952). (24) J. H. Draize, "Procedures for the Appraisal of Chemicals in Food, Drugs and Cosmet- ics Section on Dermal Toxicity," Food, Drug and Cosmetic Law y., 679 (1955). (25) J. H. Draize, "The Skin Game (An Editorial)," Int. Record of Med., 169, 37 (1956). (26) M. V. Freeman, J. H. Draize and P. K. Smith, "Some Aspects of Mechanism of Toxicity of Thioglycolate," y. Pharmacol. Expt. Therap., 118, 296 (1956). (27) M. V. Freeman, J. H. Draize and P. K. Smith, "Some Aspects of the Absorption, Distri- bution and Excretion of Sodium Thioglycolate," Ibid., 118, 304 (1956). (28) J. H. Draize, F. X. Wazeter, E. A. Kelley and R. E. Zwicky, "Ethanolamines in Topi- cal Preparations," Proc. Sci. Sect. Toilet Goods •lssoc., No. 27, 12 (1957). (29) J. H. Draize "Cutaneous Toxicity of Boric Acid Preparations," (in process of publica- tion).