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J. Cosmet. Sci., 53, 193-197 (May/June 2002) Abstracts Journal of the Society of Cosmetic Chemists Japan Volume 35, No. 1, 2001 Basement Membrane Damage, a Sign of Skin Early Aging, and Laminin 5, a Key Player in Basement Membrane Care Satoshi Amano Skin Biology Research Laboratories, Shiseido Life Science Research Center Skin is composed of the epidermis and the dermis, whicll are separated by the epidermal basement membrane. This membrane plays an important role in maintaining the skin structure by forming anchoring complex. It also controls proliferation and differentiation of basal cells in the epidermis and maintains the polarity of the epidermis. Disruption and reduplication of the epidermal basement membrane have been reported in skin from elderly people. Indeed, they are also seen in facial skin of people in their late 20s and early 30s, when changes in skin surface texture take place. Such damage and alteration are thought to be signs of early aging of skin, which might lead to the formation of wrinkles and sagging. Therefore, early basement membrane care could be an effective approach to prevent apparent skin aging. Laminin 5 is a glycoprotein and a component of anchoring complex in the epidermal basement membrane, playing an important role in the adhesion of epidermis to dermis. Purified laminin 5 stimulates the formation of epidermal basement membrane in a skin quivalent model and in epidermal sheet gra•ing in vivo. Furthermore, basement membrane formation is also enhanced by substances that stimulate laminin 5 synthesis in the skin equivalent model, as well as by purified laminin 5. These results suggest thatlaminin 5 itself and substances that stimulate laminin 5 synthesis could be effective players in basement membrane care. The Development of Quick Drying Nail Enamels Katsuyuki Kaneko, Ryota Yamasaki, Toshihito Yabu, Yoshikazu Soyama, Yoshimaru Kumano, Isamu Kaneda, Toshio Yanaki Product Development Center, Basic Research Center, Shiseido Co., Ltd. Nail enamels are very popular as a point makeup product next to lipsticks. Recently the number of user steadily increases with the prosperity of nail salons and nail art. This popularity of nail enamel put it more important position. The qualities required in nail enamel are speed of drying, even formation of film with high gloss, non irritant against the nail, and long lasting luster and finish. There is a strong growing demand for quicker drying nail enamels in recent markets, and several products are found. However, with conventional technologies, there is a limit in reducing the drying time, because of its poor appearance. This paper describes the technologies of fast drying nail enamels with the example of"dip-in - water" nail enamel. Although the process of drying is- usually regarded as solvent evaporation, in the case of developing this new nail enamel, the drying of nail enamel is considered as precipitation process of film former. This unique idea made it possible to reduce drying time dramatically with the help of water. A New Method for Evaluating Optical Traits of Stereoscopy of Face Masahide Shimoyama, Manabu Fuse, Koichi Shimmoto, Tsuyoshi Ogihara Research & Development Division, KOSE Corporation In the functions of the cosmetics, one of the crucial points is to represent the stereoscopy. Now its objective evaluation is required. Though the facial stereoscopy by the makeup is created through emphasizing the light and shade, its effectiveness until now has been evaluated by human senses such as the sense of sight. Obtaining an objective evaluation is quite difficult. A series of methods that are proposed by this study can help resolve this problem. This study proves that facial light and shade can be directly measured in a short time, enabling the calculation of the 3D facial traits and stereoscopy brought by the traits. The assembled device was designed to irradiate * These abstracts appear as they were originally published. They have not been edited by the Journal of Cosmetic Science. 193