378 JOURNAL OF COSMETIC SCIENCE scores (4.5 or greater) in the lower eyelid, nasolabial groove, cheek, and the corner of the mouth. Table III shows the wrinkle scores in eight areas of the face in 70 Japanese females using the same photoscale. In the group aged 20-29 years, the mean score was between 1 and 2 in all areas except the forehead, which was consistent with our previous study ( 6). As seen in Caucasian females, the wrinkle scores in all areas increased with age. Figure l(A-H) compares the results between the Caucasian and Japanese females in each area of the face in each age group. Forehead. The wrinkle scores were significantly lower in Japanese females than in Cau­ casian females in the groups aged 20-29 and 40-49 years, slightly lower in Japanese females than in Caucasian females in the groups aged 30-39 years, but similar between Japanese and Caucasian females in the groups aged 50-59 and 60-69 years (Figure lA). Glabella. The wrinkle scores were significantly lower in Japanese females than in Cau­ casian females in the groups aged 20-29, 30-39, 40-49, and 50-59 years, but similar between Japanese and Caucasian females in the groups aged 60-69 years (Figure lB). Upper eyelid. The wrinkle scores were significantly lower in Japanese females than in Caucasian females in the groups aged 20-29 and 30-39 years, slightly lower in Japanese females than in Caucasian females in the groups aged 40-49 years, but similar between Japanese and Caucasian females in the groups aged 50-59 and 60-69 years (Figure lC). Corner of the eye. The wrinkle scores were significantly lower in Japanese females than in Caucasian females in the groups aged 20-29, 30-39, and 40-49 years, but similar between Japanese and Caucasian females in the groups aged 50 years or more (Figure 1D). Lower eyelid. In all age groups (20-69 years), Japanese females showed significantly lower wrinkle scores than Caucasian females (Figure lE). Nasolabial groove. The wrinkle scores were significantly lower in Japanese females than in Caucasian females in the groups aged 20-29, 30-39, 40-49, and 50-59 years, but similar in the groups aged 60-69 years (Figure lF). Cheek. In all age groups (20-69 years), Japanese females showed significantly lower wrinkle scores than Caucasian females (Figure lG). Corner of the mouth. In all age groups (20-69 years), Japanese females showed significantly lower wrinkle scores than Caucasian females (Figure lH). COMPARISON OF LOWER CHEEK SAGGING BETWEEN CAUCASIAN AND JAPANESE FEMALES Table IV compares the lower-cheek sagging scores between the Japanese and Caucasian females. In the Caucasian females as well as in the Japanese females, the sagging scores increased with age. Figure 2 compares subzygomatic sagging between Caucasian and Japanese females in each age group. The sagging scores did not significantly differ between Caucasian and Japanese females in the groups aged 20-29 and 30-39 years, but were significantly higher in Caucasian females than in Japanese females in the groups aged 40 years or more.

A u ... 0 u B 5 3 a:xxxa 00 2 20a 5 4 .. 3 . 000 20■ AGE-RELATED FACIAL WRINKLING ** 00 a:x::x:x, aa. CXXX) CXXX) 00 30■ 40■ 50a 60a Age-group (years) a:x::x:x,WX' 30. 40■ 50a 60a Age-group (years) 379 □ Caucasian m Japanese □ Caucaaian □ Japanese Figure 1. Comparison of wrinkle scores between Caucasian and Japanese females. (A): Forehead. (B): Glabella. (C): Upper eyelid. (D): Corner of the eye. (E): Lower eyelid. (F): Nasolabial groove. (G): Cheek. (H): Corner of the mouth. ***, **, *: p 0.001, 0.01, 0.05, respectively. (Continued on pp. 380-382) In this study, photos were taken with the subjects' eyes open. Wrinkle score assessment in the upper eyelid was possible in all Japanese females but was impossible in the 16 Caucasian females with markedly depressed upper eyelids (data not shown). DISCUSSION We compared wrinkle and sagging scores between Caucasian females living in North