ABOUT SCC: Founded in 1945, the SCC is the oldest and largest 501(c)3 membership organization serving the cosmetics and personal care industry. Dedicated to the advancement of cosmetic science, SCC headquarters provides unparalleled education, resources and networking for nearly 6,000 members globally and via 19 chapters across Greater North America. Visit www.scconline.org for more information. MEMBERSHIP MEMBER BENEFITS INCLUDE: z Complimentary digital subscription to the Journal of Cosmetic Science, featuring the latest advances in cosmetic science (including access to issues dating back to 1947). z Discounted and/or free registration for continuing Education (webinars, lectures, hands-on lab instruction, and more) providing access to cosmetic science information for all experience levels. To keep your professional edge in this dynamic, growing industry, JOIN US TODAY! WWW.SCCONLINE.ORG/MEMBERSHIP With the Society of Cosmetic Chemists, the oldest & largest professional association focused on providing the best cosmetic science education, you join a fantastic network of formulators, marketers, suppliers, academics and regulators. noun: Joining a global community of nearly 6,000 cosmetics and personal care industry professionals, just like you! ޖPHPEԥUޙ6+LS z Opportunities to participate in a wide range of education and networking events at 19 affiliated Chapters across Greater North America. z Discounted registration to the Annual Meeting, the premiere event in the cosmetics and personal care community with two full days of education on the latest industry innovations and research. AND SO MUCH MORE!
J. Cosmet. Sci., 71, 53–64 (March/April 2020) 53 Antiaging Potential of Fucoxanthin Concentrate Derived from Phaeodactylum tricornutum SO YOUNG KANG, HUIJI KANG, JI EUN LEE, CHAN SONG JO, CHANG BAE MOON, JAEHYOUN HA, JAE SUNG HWANG, and JONGKEUN CHOI , Department of Chemical Engineering, Chungwoon University, Incheon 22110, Korea (S.Y.K., H.K., J.C.), Graduate School of Biotechnology, Kyung Hee University, Yongin 17104, Korea (J.E.L., C.S.J., J.S.H.), R&D Center, Outin Futures Co. Ltd., Seoul 06178, Korea (C.B.M.), Skin Research Center, IEC Korea, Suwon 16690, Korea (J.H.) Accepted for publication September 13, 2019. Synopsis The aim of the study was to investigate the potential of a fucoxanthin concentrate prepared from Phaeodactylum tricornutum as a wrinkle care cosmetic agent. The concentrate (up to 25 μg/ml) did not affect the proliferation of human fi broblasts. In addition, the concentrate signifi cantly increased procollagen synthesis in the fi broblasts at 12.5 and 25 μg/ml however, it signifi cantly decreased the expression of matrix metalloproteinase (MMP)-1, MMP-2, and MMP-9 at 25 μg/ml. In a follow-up study, a wrinkle care cream containing 0.03% of fucoxanthin concentrate was prepared and tested in women (aged 35–50 years, n = 21) for 8 weeks. The cream was applied twice daily. Safety assessment of the cream was carried out visually. In addition, interviews were conducted to investigate if adverse events such as erythema, edema, scaling, itching, stinging, burning, tightness, or prickling had occurred. No symptoms that threaten skin safety were reported. Evaluation of wrinkles around the eyes using the replica method showed a statistically signifi cant decrease in wrinkles at week 8. Moreover, skin moisture and elasticity increased signifi cantly from week 4. These results suggest that the fucoxanthin concentrate has no adverse effects on the skin and can be used as an active ingredient in wrinkle care cosmetics. INT RODUCTION The skin is directly exposed to the external environment therefore, it plays an important role in maintaining homeostasis of the human body by protecting it from external factors such as temperature, humidity, pathogens, and ultraviolet (UV) rays (1). However, skin cells are damaged by various harmful factors, such as pollutants, strong UV rays, stress, and malnutrition (2–5). As aging progresses and damages caused by the aforementioned factors accumulate, changes in the biochemical activities of the skin occur, which lead to Address all correspondence to Jongkeun Choi at jkchoi@chungwoon.ac.kr.
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