PREVENTION OF HAZARDS FROM CHRONIC TOXICITY OF COSMETICS 329 Cold Permanent Waving Preparations Thioglycolates, thiolactates and related compounds are widely used but are very reactive chemically and highly toxic. These compounds shotfid be in the C.-W.R. category. They shotfid be subject to rigid specifications so that impurities, including dithio derivatives and heavy metals, are excluded. The maximum concentration allowed should be 8•o (when sold retail) and the maximum pH 9.5. The hands of hairdressers using these preparations should be protected. ACKNOWL•DGEUENT The meeting was made possible by the generous support of Unilever, Ltd., Thomas Hedley and Co., Ltd., Beecham Group, Ltd., Boots Pure Drug Co., Ltd., Imperial Chemical Industries, Ltd., and D. R. Collins, Ltd. Participants: Mr. M. Ainsworth Mr. L. T. Bowerman Professor E. Boyland Professor C. D. Cainan Professor A. Castille Professor Sv. Dalgaard-Mikkelsen Dr. J. H. Draize Professor H. Druckrey Dr. W. Eckardt Professor A. C. Frazer Dr. L. Golberg APPENDIX Chemical Defence Experimental Establishment, Porton Down, Wilts., England. Thomas Hedley and Co. Ltd., Newcastle-upon- Tyne, 1, Co. Durham, England. Chester Beatty Research Institute, Fulham Road, London, S.W.3, England. St John's Hospital for Diseases of the Skin, Lisle Street, London, W.C.1, England. Institut de Pharmacie, Universit• de Louvain, Louvain, Belgium. Afedlingen for farmakologi og toksikologi, Copen- hagen V, Denmark. Food and Drug Administration, Washington 25, D.C., U.S.A. Laboratorium der chirurg. Universitats-Khnik, Freiburg im Breisgau, Germany. Waldweg 2a, Bad Segeberg/Holstein, Germany. University of Birmingham Medical School, Birm- ingham, 15, Warwicks., England. British Industrial Biological Research Association, 93 Regent Street, London, W.1, England.

330 Dr. R. Goulding Dr. M. R. Gurd Professor A. Haddow Professor Dr. G. Hecht Dr. H. W. Hibbott Professor O. H6gl Dr. A. Lafontaine Dr. G. de Meuron Dr. D. L. Opdyke Dr. B. L. Oser Mr. J. McL. Philp Apotheter I. Pint•r Mr. C. Pugh Professor L. Schmid Professor R. Truhaut JOURNAl. OF T}• SOCIETY OF COS•mT•C Ministry of Health, Savile Row, London, W. 1. Boots Pure Drug Co. Ltd., Pennyfoot Street, Nottingham, Notts., England. Chester Beatty Research Institute, Fulham Road, London, S.W.3, England. Pharmakologisches Institut, Bayer-Werke, Wup- pertal-Elberfeld, Germany. D. R. Collins Ltd., Raans Road, Amersham, Bucks., England. Service fdd•ral de l'hygi•ne publique, Berne, Switzerland. (World Health Organisation), Institut d'Hygi•ne et d'•piddmiologie, 14, me Juliette Wystman, Brussels, Belgium. J. R. Geigy, S.A., Basel, Switzerland. The Proctor and Gamble Company, Cincinnati, 0., U.S.A. Food and Drug Research Laboratories Inc., New York City, N.Y., U.S.A. Unilever, Ltd., Shambrook, Beds., England. Institut far Ern•hrung, Budapest IX, Hungary. County Laboratories, Ltd., Brentford, l•liddex., England. Lehrkanzel far Lebensmittelchemie an der Universit•t Wien, Wien IX, Austria. Facult• de Pharmacie, Universit• de Paris, Paris 6c, France. Dr. J.P. K. van der Steur Dr..1. G. van Esch Dr. P. Velon l•lr. J. B. Wilkinson Unilever, N.V., Rotterdam, Holland. Rihks Instituut voor de Volksgezondheid, Utrecht, Holland. Socidtd Lancome, 60 Avenue Marceau, Courbevoie, France. Unilever, Ltd., Isleworth, Middex., England.