936 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS Dichlorophcne, silylation and gas-liquid chromatography of, 683 Dihydroergotamine methanesulfonate, vaso- constricting effect of, 299 Dimethyl sulfoxide, effect on mechanical properties of stratum comeurn strips, 129 Drugs, photosensitizing, influence of ultra- violet irradiation on properties of, 155 Drum mixers, horizontal, rotation of free flowing granular material in, 205 rotary, kinetic angle of repose of powders in flights of, 37 rotating, evaluation of, in continuous mixing of particulate solids, 3 Elasticity of skin, measurement of, 417 Emulsifiers, theoretical interpretation of HLB scheme for rating of, 193 Emulsions, aerosol, stabilization of, 377 geometry of, with emphasis on phases re- lationships, state of subdivision, and physical properties, 141 methacrylate copolymer, alkali-thicken- able, use of, 471 micro-, theoretical advances, 193 prediction and evaluation of stability of, with ultracentrifugal stress, 393 surfactant location and required HLB for, 365 Encapsulation, micro-, techniques, applica- tions and problems, 85 Ethanol, corrosive acidity of, and effect on degradation of aerosol products and packages, 183 •/Ethyl cellulose, acid esters of, physical measurements of, 281 Feathers, red, identification of chromo- phores of, 77 Fibers, keratin, prediction of dry extension properties of, from wet extension data, 639 Fihn formers useful for hair sprays, physi- cal measurements of, 281 Fihns, aerosol, release of various ingredients from, 667 monomolecular, as model for study of photosensitized reactions, 155 Flowability of bulk particulate solids, effect of glidant addition on, 483 Fluids, Newtontan and non-Ncwtonian, mixing of, 541 Fluoride, gas chromatographic determina- tion of, in dental creams, 533 Foams, aerosol, stabilization of, 377 Follicles, hulnan hair, metabolism and con- trol mechanisms of, 901 Formaldehyde, effect on mechanical proper- ties of stratum corneum strips, 129 Formic acid, effect on mechanical properties of stratum corneum strips, 129 Gelatin, gels, applications of rigidity and yield values in study of, 427 reaction of propylene glycol alginatc with, 441 Gels, formation of, in aqueous solutions of polar organic compounds by use of Laponite clay, 237 gelatin and Laponite, applications of rigidity and yield values in study of, 427 Gentian Violet, release of, from aerosols containing film-forming agents, 667 Germicides, measurement of, deposited on skin, 521 Glidant, effect of addition of, on flowability of bulk particulate solids, 483 Growth of human skin epithelial cells in vitro, effect of retinoic acid on, 925 Guinea pigs, skin of, effect of dimethyl sulf- oxide and other reagents on mechani- cal properties of, 129 solar simulator sunscreen evaluations in, 6O7 Hair, follicles, metabolism and control mechanisms of, 901 mechanism of bleaching of, 875 red, identification of chromophores of, 77 Hair sprays, physical measurements of fihn formers useful for, 281 in study of effect of valve body orifice size on propellant/concentrate ratio, 661 Hardness, of creams, changes in, upon pro- duction scale-up, 625 of film formers useful for hair sprays, measurement of. 281 Heat exchanger, Votator-type, for determi- nation of quality of creams upon pro- duction scale-up, 625 Hexachlorophene, determination of, by gas-liquid chromatography of its tri- methylsilyl derivative, 683 Histidase activity in skin after ultraviolet irradiation, 817 HLB, required to form oil/water emulsion, 365 scheme for rating emulsifiers, theoretical interpretation, 193 Hoppers, problematical aspects of flow of particulate materials from, 53 Hygiene in manufacture and preservation of toiletties and cosmetics, complex factors involved, 719 hnmunodiffusion in agar for study of rela- tionships between types of protein ex- tracted from human epidermis, 169 •/Inorganic agents, mechanisms of thickening by, 347 Interfacial region around propellant drop- lets in aerosol emulsions stabilized with molecular complexes, polymolecular structure of, 377 International Federation of Societies of Cosmetic Chemists, Sixth Congress, 376 Isovaleric acid, odor of, correlated with

JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS 937 molecular shape by scanning computer, 99 Keratin, adherence of vegetable bath oils to, 613 fibers, prediction of dry extension proper- ties of, from wet extension data, 639 modification of, in hair bleaching, 875 Keratinization, and chemical differentiation in epidermis, 583 of human skin epithelial cells in vitro, effect of retinoic acid on, 925 Laponite, clay, as synthetic inorganic gelling agent for aqueous solutions of polar organic compounds, 237 gels, applications of rigidity and yield values in study of, 427 Liquid crystal structure of molecular com- plexes in stabilization of aerosol emul- sions and foams, 377 Lithium bromide, in extraction of pro- teins from human epidermis, 169 Manufacture of toiletries and cosmetics, factors influencing hygiene of, 719 Mechanical properties of stratum corneum strips, effect of dimethyl sulfoxide and other reagents upon, 129 Melanin, changes in, in hair bleaching, 875 Metabolism and control mechanisms of hu- man hair follicles, 901 Methacrylate copolymer emulsions, alkali- thickenable, use of, 471 Metrication, conversion factors, symbols and definitions, 74 Mice, in phototoxicity testing of cosmetic materials, 825 Microscope-closed circuit television system, for observation of subcutaneous micro- vascular responses in bat wing to ex- ogenous agents, 845 Microscopy of very fine particles, 563 Mixing, and blending of powders, 205 continuous, of particulate solids, 3 and index of homogeneity in sa•npling and assessment of powder mixtures, 259 V of Newtonian and non-Newtonian fluids, 541 Molecular complexes in stabilization of aerosol emulsions and foams, 377 Molecular shape, correlation of, with pri- mary odor, by scanning computer, 99 Odors, determination of, using olfactometer, 289 elimination of, evaluation of several chemicals for, 801 primary, correlation of, with molecular shape by scanning computer, 99 Olfactometer, application of, 289 for evaluation of chemicals used for elimi- nation of undesirable odors, 801 Organic compounds, polar, formation of gels in aqueous solutions of, by use of Laponite clay, 237 •,Particles, of different sizes, segregation in drutn mixers, 205 •J flow of, from storage hoppers, 53 size of, effect on area of peak of thermo- gram, 221 size of, effect on glidant efficiency and •,t flowability of bulk particulate solids, 483 x/ size of, effect on kinetic angle of repose, 37 • size of, in powder aerosols, 553 size distribution of, of creams, changes upon production scale-up, 625 it' small, microencapsulation techniques, 85 solid, continuous mixing of, 3 k/very fine, physical, chemical, and optical properties of, 563 Perfume, phototoxic potential of, 695 Permeability of epidermis, effects of sur- factants and solvents on, 853 Pharmaceuticals, potential use in, of propyl- ene glycol alginate reactions with gela- tine, polyvinyl alcohol, and starch, 441 sampling and assessment of powder mix- tures for, 259 Phenol, effect on mechanical properties of stratum corneum strips, 129 Phenylephrine hydrochloride, vasocon- stricting effect of, 299 Pheomalanoproteins, red, structure of, 77 Photosensitized reactions, monomolecular films as model for study of, 155 Phototoxic index, for comparison of surface pressure changes due to irradiation of drug-film system, 155 Phototoxicity, of cosmetic materials, 825 of perfumes containing bergamot, 695 Pigments, red, of hair and feathers, identi- fication of chromophores of, and rela- tion to black melanogenesis, 77 Plasticizcrs, influence of, on rate of release of Gentian Violet from aerosols, 667 Polyethylene glycol 400 monolaurate in germicidal systems deposited on skin, 521 Polymers, influence of, on rate of release of Gentian Violet from aerosols, 667 methacrylate, alkali-thickenable, use of emulsions of, 471 Polyvinyl alcohol, reaction of propylene gly- col alginate with, 441 Powders, aerosol, problems and recent de- '4 velopments, 553 dry state, and dispersion in liquids, v changes in physical, chemical, and opti- cal properties, 563 fine, flowability of, on admixture with •/ coarse material, 483 kinetic angle of repose of, 37 •, mixing and blending of, in drum mixer, 2O5 thermal conductivity effects in differential thermal analysis of, 221