772 JOURNAL OF THE SOCIETY OF COSMETIC CItEMISTS (172) (173) (174) (175) (176) (177) (178) (179) 080) 081) (182) (183) 084) (185) (186) (187) (188) (189) (19o) (191) (192) (193) (194) (195) (196) (197) 098) (199) Vogel, H. G., Kobelt, D., Korting, G. W. and Holzmann, W. Studies on the mechanical properties of rats' skin in correlation to sex and age. Arch. Klin. Exp. Dermatol. 239 296 (1970). Sodeman, W. A. and Burch, G. E. A direct method for the estimation of skin distensi- bility with its application to the study of vascular states. J. Clin. Invest. 17 785 (1938). Evans, J. H. and Siesennop, W. W. Controlled quasi-static testing of human skin in vive. 7th Int. Con. t• Med. Biol. Engng, Stockholm 27 4 (1967). Harkness, M. L. R. and Harkness, R. D. Changes in the physiological properties of the uterine cervix of the rat during pregnancy. J. t'hysiol. 148 524 (1959). Harkhess, R. D in Illingworth, C. Factors affecting the strength of the dermis in Wound healing 243 (1966) (Churchill, London). Schade, H. Untersuchungen zur Organfunktion des Bindegewebes. I. Die Elasticitaets Funktion des Bindegewebes und die intravitale Messung ihrer Stoerungen. Z. Exp. t'athol. Ther. 11 369 (1912). Finlay, B. Dynamic mechanical testing of human skin in vive. J. Biomechanics 3 557 (1970). Laden, K. and Morrow, R. Torsional measurements on skin. J. See. Cosmet. Chem. 21 417 (1970). Eldon, H. R. in A Treatise on the skin 1 Biophysical properties of the skin (1971) (Wiley, Interscience, New York). Blank, I. H. and Finesinger, J. E. Electrical resistance of the skin: effect of size of elec- trodes, exercise and cutaneous hydration. Arch. Neurol. t'sychiat. 56 544 (1946). Richter, C. P. Physiological factors involved in the electrical resistance of the skin. Amer. J. t'hysiol. 88 596 (1929). Lawler, J. C., Davis, M. J. and Griffith, E. C. The electrical impedance of the surface sheath of skin and deep tissues. J. Invest. Dermatol. 34 301 (1960). Lewis, T and Zotterman, Y. Vascular reactions of the skin to injury VIII. The resistance of human skin to constant currents in relation to injury and vascular response. J. t'hysiol. 62 280 (1927). Rosendal, T. Studies on the conducting properties of the human skin to a direct current. Acta Physiol. Scan& 5 130 (1943). Burns, R. C. A study of skin impedance. Electronics 190 (1950). Allenby, A. C., Fletcher, J., Schock, C. and Tees, T. F. S. The effect of heat, pH and organic solvents on the electrical impedance and permeability of excised human skin. Brit. J. Dermatol. 81 31 (1969). Kligrnan, A.M. Topical pharmacology and toxicology of DMSO. Part I. J. Amer. Med. Ass. 193 796 (1965). Menre, D. D. and Stoughton, R. B. Dimethyl acetamide (DMAC) and dimethylform- amide (DMFA) effect on percutaneous absorption. Arch. Dermatol. 92 585 (1965). Matoltsy, A. G., Dowries, A.M. and Sweeney, T. M. Studies of the epidermal water barrier. Pt. II. Investigation of the chemical nature of the water barrier. J. Invest. Dermatol. 50 19 (1968). Vinson, L. J., Singer, E. J., Koeler, W. R., Lehman, M.D. and Masurat, T. The nature of the epidermal barrier and some factors influencing skin permeability. To.xicol. Appl. t'harmacol. 7 7 (1965). Choman, B. R. Determination of the response of skin to chemical agents by an in vitro procedure. I. Effect of unbuffered and buffered artionic solutions. J. Invest. Dermatol. 37 263 (1961). Emery, B. E. and Edwards, L. D. The pharmacology of soaps. J. Amer. t'harm. Ass. (Sci.) 29 251 (1940). Choman, B. R. Determination of the response of skin to chemical agents by an in vitro procedure. II. Effects of aqueous anionic, cationic and non-ionic surfactant solutions. J. Invest. Dermatol. 40 177 (1963). Puttnam, F. W. and Neurath, H. Interaction between proteins and synthetic detergents. J. Biol. Chem. 159 195 (1945). Lansdown, A. B. G. and Grasso, P. Physico-chemical factors influencing epidermal damage by surface-active agents. Brit. J. DermatoL 86 361 (1972). Puttnam, N. A. and Baxter, B.H. Spectroscopic studies of skin in situby attentuated tota reflectance. J. $oc. Cosmet. Chem. 18 469 (1967). Comaish, S. Infra-red studies of human skin in vive by multiple internal reflection. Brit. J. Dermatol. 80 522 (1968). Parker, F. S and Ans, R. Infra-red studies of human and other tissues by the attenuated total reflection technique. Anal. Blochem. 18 414 (1967).
Book reviews I.U.P.A.C. Editor: M. N. Kolosov. The chemistry of natural products-7. Pp. viii -•- 304 q- Ill. (1971). Butterworths, London. oe7.80. $23.40. This work is a collection of the plenary lectures given at the VIIth International Symposium on the Chemistry of Natural Products, held in Riga, U.S.S.R. in June 1970. In general the topics covered illustrate the wide application of the principles of modern organic chemistry to important and complex problems of biochemistry and mole- cular biology. The quality of the contribu- tions is outstanding, which is not surprising when one notes the lecturers. Thus, Prof. D. H. R. Barton describes approaches to the synthesis of the tetra- cyclines Prof. H. G. Khorana gives an account of his brilliant synthesis of yeast alanine transfer RNA, while Prof. R. B. Woodward continues the saga of attempts to synthesize vitamin Bx2. Other contributions of note are Prof. E. Lederer's on present knowledge of the chemistry of the cell wall of Mycobacteria and related organisms Naka- nishi's account of the ecdysones and Van Deenen on the chemistry of phospholipids and biological membranes. Antimetabolite chenfistry and enzyme catalysis and topo- graphy are also dealt with. An important paper, surveying the develop- ment of natural product chemistry in the U.S.S.R. over the last 10 years, was given by Prof. M. M. Shemyakin, whose sudden death occurred during the meeting. This volume is to be recommended for general reading and essential to any organic chemist interested in the application of his subject to the study of the biological sciences. A. G. BROWN 773 THE APPLICATIONS OF MOLECULAR DISTILLATION. J. Hollo, E. Kurucz and A. Borodi. Pp. 210 q- I11. (1971). Akad6miai Kiad6, Budapest. oe1.75. This book surveys the principal uses of molecular distillation up to the mid-1960s, from a practical viewpoint. The theoretical aspects of the process are briefly dealt with in an introductory section, and there is an account of the available t.•pes of still and ancillary equipment. The main part of the book is a comprehensive literature review (226 references, with a further 400 or so in a sup- plementary classified list) covering laboratory analytical and preparative applications as well as industrial uses. The greatest emphasis, naturally enough, is on the processing of glyceride oils and the production of vitamin concentrates, some such processes being de- scribed in useful detail other topics such as tall oils, mineral oils and plasticizers are more briefly discussed. The book has the common fault of trans- lated technical literature, an awkwardness of expression which leads sometimes to a lack of clarity, particularly in the theoretical section. The brief chemical process descrip- tions contain one or two minor lapses from strict accuracy. However, the book justifies its unpretentious claim to be a 'modest appendix' to the monographs already available it may be found of use as a practical introduction to the subject and as a key to the literature. P. L. WILLIAMS MARTINDALE: THE EXTRA PHARMA- COPOEIA. 26th edn. Pp. xviq-2320 (1972). The Pharmaceutical Press, London. oe14. The Extra t'harmacoj•oeia is so well known that a new edition calls for little more than a
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