Figure 4(a). SEM of a replica from untreated forearm of a 49 year old male (x 188). (b) An adjacent site 300 rain after application of Emollient C, again showing a flattening of contour.

.-• . •1 •. '-•- - ' •'' - • • • --V ß •-• • ..... •. •%•.•. . _.• ..•.•..•... •.• •.• . .• •. • ..: . : . .. ..-'•.,•- ?.".••.•.. •._ •. :• •:.._• .. :. ß . • . ..t.. • • ....• ." •:.. ß --.., * .- • ..' • . .. • -.• . -. : •.• •_ • , .: . •..•.• •.: '• 4'-- ,., -. . .t • .• *--:-• . •.. . . . .:-. ' ...•. '- . :... .•'...•. - •.. ...:: . •. ß . *• .? • -. •.. •'• .•.• t•""' , -[ .. -. .... . '•. .--' * '"*• • , •' '. c•T z*: :': -•½'• • ,:.. ' . :. . . ...t* . .: .., .. .....• ...: •.• . •, * . . • .-. ,. .. .. . ._ .. .-. ,•- . ..* -. . .•, • •**' ' . t. r• ' ,-..•. , *• ..} ..... - ..• . ..,- • • ' •. . , ....a , . ... "*' • "'• . • ..... . • •:•' -t': :.- t.- • • •.' ., :,. --.-.... • .- . , . • : ß "' . .: • - Figure 5 (a). SEM of a replica from the untreated leg of a 55 year old female (x 840). (b) An adjacent site 120 min after application of Emollient B, (x 894). Individual corneocytes appear more prominent. In some areas 'rolled' thickened edges of the corneocytes can be discerned.