472 JOURNAL OF COSMETIC SCIENCE The effect of CAAS was comparable to that of T and was higher than that of AA. Occlusion of the formulations may be an important factor in skin hydration. Because w/o creams had a higher lipid content, increased conductance values were observed. ACKNOWLEDGMENT This project was supported by the Research Fund of Istanbul University, project no. UDP-199/003092003. REFERENCES (1) A. V. Rawlings, I. R. Scott, C. R. Harding, and P.A. Browser, Stratum corneum moisturization at the molecular level,]. Invest. Derrnatol., 103, 731-740 (1994). (2) H. Mireles-Rocha, I. Galindo, M. Huerta, B. Trujillo-Hernandez, A. Elizalde, and R. Cortes-Franco, UVB protection with antioxidants: Effects of oral therapy with d-alpha-tocopherol and ascorbic acid on the minimal erythemal dose, Acta Derm. Venerol., 82, 21-24 (2002). (3) P. M. Maia Campos and G. M. Silva, Ascorbic acid and its derivatives in cosmetic formulations, Cosmet. Toiletr., 115, 59-62 (2000). (4) C. Fox, Advances in the cosmetic science and technology of topical biactive materials, Cosmet. Toiletr., 112, 67-84 0997). (5) S. Tamburic, G. Abamba, and J. Ryan, Moisturizing potential of d-a-tocopherol, Cosrnet, Toiletr., 114, 73-82 0999). (6) F. Gonzalez, Human cytochromes P450: Problems and prospects, TIPS Rev., 13, 346-352 (1992). (7) K. Anbarasi, G. Kathirvel, G. Vani, G. Jayaraman, and C. S. Shyamala Devi, Cigarette smoking induces heat shock protein 70 kDa expression and apoptosis in rat brain: Modulation by bacoside A, Neurosci., 138, 1127-1135 (2006). (8) M. Valko, C. J. Rhodes, J. Moncol, M. Izakovic, and M. Mazur, Free radicals, metals and antioxidants in oxidative stress-induced cancer, Chern.-Biol. Interact., 160, 1-40 (2006). (9) A. Valencia and I. E. Kochevar, Ultraviolet A induces apoptosis via reactive oxygen species in a model for Smith-Lemli-Opitz syndrome, Free Rad. Biol. Med., 40, 641-650 (2006). (10) S. R. Pinnell, H. Yang, M. Omar, N. Monteiro-Riviere, H. V. de Buys, L. C. Walker, Y. Wang, and M. Levine, Topical L-ascorbic acid: Percutaneous absorption studies, Derrnatol. Sttrg., 27, 137-142 (2001). (11) M. D. Carbonate and M.A. Pathak, Skin photosensitizing agents and the role of reactive oxygen species in photoaging,J. Photochem. Photobiol. B, 14, 105-124 0992). (12) C. L. Philips, S. B. Combs, and S. R. Pinell, Effects of ascorbic acid on proliferation and collagen synthesis in relation to the donor age of human fibroblasts,]. Invest. Dennatol., 103, 228-232 (1994). (13) H. Padh, Cellular functions of ascorbic acid, Biochem. Cell. Biol., 68, 1166-1173 (1990). 04) K. Kameyama, C. Sakai, and S. Kondoh, Inhibitory effect of magnesium L-ascorbyl-2-phosphate (VC-PMG) on melanogenesis in vitro and in vivo,]. Acad. Dermatol., 34, 29-33 0996). 05) H. Z. Zhai and H. I. Maibach, Skin whitening agents, Cosmet. Toiletr., 116, 20-25 (2001). (16) P. Spiclin, M. Gasperlin, and V. Kmetec, Stability of ascorbyl palmitate in topical microemulsions, Int. J. Pharrn., 222, 271-279 (2001). (17) E. Kleszczewska, L-ascorbic acid-Clinical use, toxicity, properties, methods of determination and application in chemical analysis, Pharmazie, 55, 640-644 (2000). (18) G. R. Buettner and B. A. Jurkiewicz, Catalytic metals, ascorbate and free radicals: Combinations to avoid, Radiat. Res., 145, 532-541 (1996). (19) R. Austria, A. Semenzato, and A. Bettero, Stability of vitamin C derivatives in solution and topical formulations,]. Pharm. Biomed. Anal., 15, 795-801 (1997). (20) M. Lopez-Torres, J. J. Thiele, Y. Shindo, D. Han, and L. Packer, Topical application of alpha-
MOISTURIZING EFFECTS OF AA, CAAS, AND TOCOPHEROL 473 tocopherol modulates the antioxidant network and diminishes ultraviolet-induced oxidative damage in murine skin, Br. J. Derrnatol., 138, 207-215 (1998). (21) U. Gi:ini.ilh.i., G. Yener, M. Uner and T. incegi.il, Moisturizing potentials of ascorbyl palmitate and calcium ascorbate in various topical formulations, Int. J. Cosmet. Sci, 26, 31-36 (2004). (22) CK, Courage + Khazaka Electronic GmbH, Information and operating instructions for the Corneom­ eter SM 810® and the software. (23) T. Barlow and J. W. Wiechers, Measuring skin hydration, Costnet. Toiletr., 114, 47-53 (1999). (24) J. W. Wiechers, Comparing instrumental and sensory measurements of skin moisturization, Costnet. Toiletr., 114, 29-34 (1999). (25) S. A. Wissing, A. Lippacher, and R. H. Muller, Investigations on the occlusive properties of solid lipid nanoparticles (SLN),j. Cosrnet. Sci., 52, 313-324 (2001).
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