653 WHAT CAUSES CURLY HAIR? (47) L. M. Dowling, K. F. Ley, and A. M. Pearce, Eds., “The protein composition of cells in the wool cortex,” in Proceedings of the 8th International Wool Textile Research Conference (7–14 February 1990), Vol. I. G. H. Crawshaw. Ed. (Wool Research Organisation of New Zealand, Christchurch, New Zealand, 1990), pp. 205–214. (48) Y. Kajiura, S. Watanabe, T. Itou, A. Iida, Y. Shinohara, and Y. Amemiya, Structural analysis of single wool fibre by scanning microbeam SAXS, J. Appl. Crystallogr., 38, 420–425 (2005). (49) L. N. Jones, M. Choleva, I. J. Kaplin, G. E. Legge, and R. W. Ollerhead, Eds., “Elemental distributions in keratin fibre/follicle sections,” in Proceedings of the 8th International Wool Textile Research Conference (7–14 February 1990), Vol. I. G. H. Crawshaw. Ed. (Wool Research Organisation of New Zealand, Christchurch, New Zealand, 1990), pp. 246–255. (50) F. J. Wortmann and H. Deutz, Thermal analysis of ortho- and para-cortical cells isolated from wool fibers, J. Appl. Polym. Sci., 68, 1991–1995 (1998). (51) F. J. Wortmann and G. Wortmann, A somewhat unexpected result from the deconvolution of DSC curves for human hair: there is no apparent relation between cortical cell fractions and hair curliness, Exp. Dermatol., 27, 292–294 (2018). (52) H. Liu and W. G. Bryson, A three-component model of the wool fibre—effects of morphology, elasticity and intermediate filament arrangement on fibre stiffness, J. Text. Inst., 93, 121–131 (2002). (53) H. W. Liu, W. G. Bryson, Z. Y. Wang, and P. Xu, An analytical model of wool crimp, Adv. Mater. Res., 146–147, 386–389 (2011). (54) D. P. Harland, J. A. Vernon, R. J. Walls, and J. L. Woods, Transmission electron microscopy staining methods for the cortex of human hair: a modified osmium method and comparison with other stains, J. Microsc., 243, 184–196 (2011). (55) K.-H. Phan, Electron Microscopy and the Characterization of Keratin Fibres (EEC Cornett Eurotex, Universidade do Minho-Guimaräes, Portugal, 1991). (56) Y. Kajiura, S. Watanabe, T. Itou, K. Nakamura, A. Iida, K. Inoue, N. Yagi, Y. Shinohara, and Y. Amemiya, Structural analysis of human hair single fibres by scanning microbeam SAXS, J. Struct. Biol., 155(3), 438–444 (2006). (57) C. Popescu and H. Höcker, Hair—the most sophisticated biological composite material, Chem. Soc. Rev., 36, 1282–1291 (2007). (58) S. Thibaut, P. Barbarat, F. Leroy, and B. A. Bernard, Human hair keratin network and curvature, Int. J. Dermatol., 46(Suppl. 1), 7–10 (2007). (59) C. R. Robbins, Chemical and Physical Behavior of Human Hair, 3rd Ed. (Springer-Verlag, New York, NY, 1994). (60) J. A. Swift, “Morphology and histochemistry of human hair,” in Formation and Structure of Human Hair. P. Jollès, H. Zahn, and H. Höcker. Eds. (Birkhäuser Verlag, Basel, Switzerland, 1997), pp. 149–175. (61) I. J. Kaplin and K. J. Whiteley, “The structure of keratin macrofibrils. Part I: Keratins of high sulphur content,” in Proceedings of the 7th International Wool Textile Research Conference. M. Sakamoto and S. Gakkai. Eds. (Society of Fiber Science and Technology, Tokyo, Japan, 1985) pp. 95–104. (62) P. Kassenbeck, “Morphology and fine structure of hair,” in Hair Research, Status and Future Aspects. E. E. Orfanos, W. Montagna, and G. Stuttgen. Eds. (Springer-Verlag, Berlin, Germany, 1981), pp. 52–64. (63) C. Orfanos and H. Ruska, Fine structure of human hair II. Hair-cortex, Arch. Klin. Exp. Dermatol., 231, 264–278 (1968). (64) R. Randebrock, Neue erkenntnisse über den morphologischen aufbau des menschlichen haares, J. Soc. Cosmet. Chem., 15, 691–706 (1964). (65) P. Kassenbeck, The Hair and Its Structure (Wella, Darmstadt, Germany, 1984). (66) D. P. Harland, “Introduction to hair development,” in The Hair Fibre: Proteins, Structure and Development. J. E. Plowman, D. P. Harland, and S. Deb Choudhury. Eds. (Springer, New York, NY, 2018), pp. 89–96.

654 JOURNAL OF COSMETIC SCIENCE (67) D. P. Harland and J. E. Plowman, “Development of hair fibres,” in The Hair Fibre: Proteins, Structure and Development. J. E. Plowman, D. P. Harland, and S. Deb Choudhury. Eds. (Springer, New York, NY, 2018), pp. 109–154. (68) L. Auber, The anatomy of follicles producing wool-fibres, with special reference to keratinization, Trans. R. Soc. Edinb., 62(1), 191–254 (1952). (69) R. E. Chapman, “The ovine arrector pili musculature and crimp formation in wool,” in Biology of the Skin and Hair Growth. A. G. Lyne and B. F. Short. Eds. (Angus and Robertson, Sydney, Australia, 1965), pp. 201–232. (70) J. J. Lemasters, V. K. Ramshesh, G. L. Lovelace, J. Lim, G. D. Wright, D. Harland, and T. L. Dawson, Compartmentation of mitochondrial and oxidative metabolism in growing hair follicles: a ring of fire, J. Invest. Dermatol., 137, 1434–1444 (2017). (71) A. J. Mickinnon, D. P. Harland, and J. L. Woods, Relating self-assembly to spatio-temporal keratin expression in the wool follicle, J. Text. Eng., 62, 123–128 (2016). (72) D. F. Orwin and J. L. Woods, Number changes and development potential of wool follicle cells in the early stages of fiber differentiation, J. Ultrastruct. Res., 80, 312–322 (1982). (73) M. S. Zamil, D. P. Harland, B. K. Fisher, M. G. Davis, J. R. Schwartz, and A. Geitmann, Biomechanics of hair fibre growth: a multi-scale modeling approach, J. Mech. Phys. Solids, 148, 104290 (2021). (74) Z. Yu, S. W. Gordon, A. J. Nixon, C. S. Bawden, M. A. Rogers, J. E. Wildermoth, N. J. Maqbool, and A. J. Pearson, Expression patterns of keratin intermediate filament and keratin associated protein genes in wool follicles, Differentiation, 77(3), 307–316 (2009). (75) J. McKinnon and D. P. Harland, A concerted polymerization-mesophase separation model for formation of trichocyte intermediate filaments and macrofibril templates 1: Relating phase separation to structural development, J. Struct. Biol., 173(2), 229–240 (2011). (76) P. I. Hynd, N. M. Edwards, M. Hebart, M. McDowall, and S. Clark, Wool fibre crimp is determined by mitotic asymmetry and position of final keratinisation and not ortho- and para-cortical cell segmentation, Animal, 3, 838–843 (2009). (77) E. Maes, F. Bell, C. Hefer, A. Thomas, D. Harland, A. Noble, J. Plowman, S. Clerens, and A. Grosvenor, Insights in human hair curvature by proteome analysis of two distinct hair shapes, J. Cosmet. Sci., 72(3), 249–267 (2021). (78) J. E. Plowman, R. E. Miller, A. Thomas, A. J. Grosvenor, D. P. Harland, and S. Deb-Choudhury, A detailed mapping of the readily accessible disulfide bonds in the cortex of wool fibers, Proteins, 89(6), 708–720 (2021). (79) E. Maes, J. M. Dyer, S. Deb-Choudhury, S. Clerens. Mapping protein crosslinks in human hair via mass spectrometry. J. Cosmet. Sci., 72(S), 655–669 (2021). (80) J. E. Plowman, D. P. Harland, S. Ganeshan, J. L. Woods, B. van Shaijik, S. Deb-Choudhury, A. Thomas, S. Clerens, and D. R. Scobie, The proteomics of wool fibre morphogenesis, J. Struct. Biol., 191(3), 341–351 (2015). (81) L. Langbein, M. A. Rogers, H. Winter, S. Praetzel, U. Beckhaus, H.-R. Rackwitz, and J. Schweizer, The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle, J. Biol. Chem., 274, 19874–19884 (1999). (82) L. Langbein, M. A. Rogers, H. Winter, S. Praetzel, and J. Schweizer, The catalog of human hair keratins. II. Expression of the six type II members in the hair follicle and the combined catalog of human type I and II keratins, J. Biol. Chem., 276, 35123–35132 (2001). (83) L. Langbein and J. Schweizer, Keratins of the human hair follicle, Int. Rev. Cytol., 243, 1–78 (2005). (84) L. Langbein, H. Yoshida, S. Praetzel-Wunder, D. A. Parry, and J. Schweizer, The keratins of the human beard hair medulla: the riddle in the middle, J. Invest. Dermatol., 130, 55–73 (2010).