HUMAN HAIR FOLLICLES 923 (17) Beatty, C. H., Peterson, R. D., and Bocek, R. M., Metabolism of red and white muscle fiber groups, Amer. J. Physiol. 204, 939-42 (1963). (18) Lowry, O. H., The quantitative histochemistry of the brain. Histological sampling, J. Histochem. Cytochertt., 1, 420-8 (1953). (19) Lowry, O. H., Roberts, N. R., Wu, M. L., Hixon, W. S., and Crawford, E. J., The quantitative histochemistry of brain. II. Enzyme measurements, J. Biol. Chem., 207, 19-37 (1954).' (20) Lowry, O. 'H., and Passonneau, J. v., The relationships between substrates and en- zymes of glycolysis in brain, Ibid., 239, 31-42 (1964). (21) Uno, H., Adachi, K., and Montagna, W., Glycogen contents of primate hair follicles, J. Invest. Dermatol., 51, 197-9 (1968). (22) Montagna, W., and Chase, H. B., Histology and cytochemistry of human skin. X. X-irradiation of the scalp, A ruer. J. A nat., 99, 415-46 (1956). (23) Adachi, K., Chow, D.C., and Rothman, S., Metabolism of glycogen in skin and the effect of radiation, Science, 135, 216-7 (1962). (24) Wotiz, H. H., Mescon, H., Doppel, H., and Lemon, H. M., The in vitro metabolism of testosterone by human skin, ]. Invest. Dermatol., 26, 113-20 (1956). (25) Gomez, E. C., and Hsia, S. L., In vitro metabolism of testosterone-4-•C and A •- androstene-3,17-dione-4-•C in human skin, Biochemistry, 7, 24-32 (1968). (26) Bruchovsky, N., and Wilson, J. D., Evidence that dihydrotestosterone is the active form of testosterone, Clin. Res., 16, 74 (1968). (27) Bruchovsky, N., and Wilson, J. D., The conversion of testosterone to 5 a-androstane-17/•- ol-3-one by rat prostate in vivo and in vitro, J. Biol. Chem., 243, 2012-21 (1968). (28) Bruchovsky, N., and Wilson, J. D., The intranuclear binding of testosterone and 5 a- androstan-17/•-ol-3-one by rat prostate, Ibid., 243, 5953-60 (1968). (29) Morris, J. M., and Mahesh, V. B., Further observations on the syndrome "Testicular Feminization," Amer. J. Obstet. Gynecol., 87, 731-48 (1963). (30) Strauss, J. S., and Pochi, P. E., Recent advances in androgen metabolism and their relation to the skin, Arch. Dermatol., 100, 621-36 (1969). (31) Lowry, O. H., Passonneau, J. v., Schultz, D. W., and Rock, M. K., The measurement of pyridine nucleotides by enzymatic cycling, ]. Biol. Chem., 236, 2746-55 (1961). (32) Butcher, R. W., Robinson, G. A., Hardman, J. G., and Sutherland, E. W., The Role of Cyclic AMP in Hormone Actions, in Weber, G., Advances in Enzyme Regulation, Per- gamon Press, Oxford, London, Edinburgh, New York, Toronto, Sydney, Paris, and Braunschweig, 1968, pp. 357-89. (33) Robinsoq, G. A., Butcher, R. W., and Sutherland, E. W., Cyclic AMP, in Boyer, P. D., Annual Review of Biochemistry, Annual Reviews, Inc., Palo Alto, Calif., 1968, Vol. 37, pp. 149-74. (34) Krishna, G., Weiss, B., and Brodie, B. B., A simple, sensitive inethod for the assay of adenyl cyclase, .l. Pharmacol. Exp. Ther., 163, 379-85 (1968•. (35) Tao, M., and Lipmann, F., Isolation of adenyl cyclase from Escherichia coli, Proc. Nat. Acad. Sci. U.S., 63, 86-92 (1969). (36) Uno, H., Allegra, F., Adachi, K., and Montagna, W., Studies of common baldness of the stumptailed macaque, I. Distribution of the hair follicles, J. Invest. Dermatol., 49, 288-96 (1967). (37) Uno, H., Adachi, K., Allergra, F., and Montagna, W., Studies of common baldness of the stumptailed macaque, II. Enzyme activities of carbohydrate metabolism in the hair follicles, Ibid., 51, 11-18 (1968). (38) Takashima, I., Adachi, K., and Montagna, W., Studies of common baldness of the stump- tailed macaque. IV. In vitro metabolism of testosterone in the hair follicles, Ibid., In press (1970).

924 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS (39) Pearhnan, W. H., and Pearlman, M. R. J., The metabolis•n in vivo of •*-androstene- 3,17-dione-7-H'• its localization in the ventral prostate and other tissues of the rat, J. Biol. Chem., 236, 1321-7 (1961). (40) Rcsko, J. A., Goy, R. X•r., and Phoenix, C. H., Uptake and distribution of exogenous testosterone-l.2-aH in t•eural and genital tissues of the castrate guinea pig, Endocri- r•ology, 80, 490-8 (1967). (41) Northcutt, R. C., Island, D. P., and Liddie, G. W., An explanation for the target organ unresponsiveness to testosterone in the testicular feminization syndrome, J. ½lin. Endocrinol. Metab., 29, 422-5 (1969). (42) Dorfman, R. I., and Dorfman, A. S., Assay of subcutaneously administered androgens on the chick's comb, Acta oendocrinol., 41• 101-6 (1962).