268 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS However, for a particular ternary system, water-surfactant-lipophile phase, it is the isotropic oily phase formation capacity of emulsions which regulates their occlusivity. The isotropic oily phase formation depends largely on the HLB value of the surfactant (19). Thus, emulsions made with surfactant of such an HLB that the emulsions form an isotropic oily phase most easily manifest the greatest occlusivity. Any additive modifying isotropic oily phase formation capacity of emulsions could eventually modify their occlusivity as we observed in the presence of humectants. By chemical nature, humectants are close to electrolytes. They may change HLB value of surfactants (20) and consequently modify isotropic oily phase formation capacity. A relationship between the formation of an isotropic oily phase and the occlusivity of emulsions has been established. This finding can provide a rapid guide in choosing emulsions of different occlusivities ranging from weaker to strong ones. Thus, it will be possible to simplify cosmetic and dermatological preparations. However, a further study is necessary to prove this relationship by doing experiments either with human subjects or i, vitro using human skin. REFERENCES (1) I. H. Blank, Factors which influence the water content of the human skin, J. Invest. Dermatol., 18, 433-440 (1952). (2) I. H. Blank, Further observations on factors which influence the water content of the stratum comeurn, J. Invest. Dermatol., 21, 259-269 (1963). (3) L. Gaul and G. B. Underwood, Relation of dew point and barometric pressure to chapping of normal skin, J. Invest. Dermatol., 19, 9-19 (1952). (4) G. Barnett, "Emollient Creams and Lotions," in Cosmetic Science and Technology, 2nd ed., M.S. Balsam and E. Sagarin Eds. (Wiley Interscience, New York, 1972), pp. 27-104. (5) F. Tranner and G. Berube, Mineral oil and petrolatum: Reliable moisturizers, Cosmet. Toilet., 93, 81-82 (1978). (6) J. B. Shelmire, The influence of oil-in-water emulsions on the hydration of keratin, J. Invest. Der- matol., 26, 105-108 (1956). (7) R. M. Handjani-Vila, B. Rondot, and F. Lachampt, Perspiratio insensibilis control by specific associations of lipids, Cosmet. Perrum., 90, 39-42 (1975). (8) J. Wepierre, M. Adrangui, and J. P. Marty, Factors in the occlusivity of aqueous emulsions, J. Soc. Cosmet. Chem., 33, 157-167 (1982). (9) D. H. Powers and C. Fox, The effect of cosmetic emulsions on the stratum corneum, J. Soc. Cosmet. Chem., 10, 109-116 (1959). (10) T. Choudhury, M. Adrangui, J.P. Marty, A.M. Orecchioni, M. Sei!,ler, and J. Wepierre, Importance of moisturizing agents on the occlusive properties of emulsions, presented at the 12th Congress of International Federation of Societies of Cosmetic Chemists, Paris, Sept. 13-17, 1982, pp 159-177. (11) R. M. Handjani-Vila, B. Rondot, and F. Lachampt, Measurement of moisturizing effect, Cosmet. Toilet, 91, 25-30 (1976). (12) M. Adrangui, F. Puisieux, M. Selllet, E. Morszanyi, and A.M. Orecchioni, Diagramroes: eau- surfactif-huile • base de perhydrosqual&ne et de Miglyol 812 ©, Pharm. Acta. Helv., 54, 214-219 (1979). (13) A. Delaunois, Biostatistics in Pharmacology (Pergamon Press, Oxford, 1973), Vol. II, pp 911-919. (14) D. Spruit, Interference of some substances with water vapor loss of human skin, Amer. Perf. Cosmet., 86, 27-32 (1971). (15) I. H. Blank, "Emollients," in The Chemistry and Manufacture of Cosmetics, 2nd ed., M. G. de Navarre, Ed. (Continental Press, Orlando, Florida, 1975), pp 15-24. (16) H. Tsutsumi, T. Utsugi, and S. Hayashi, Study on the occlusivity of oil films,J. Soc. Cosmet. Chem., 30, 345-356 (1979).

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