JOURNAL OF COSMETIC SCIENCE 132 CONCLUSION In conclusion, EPS-229 protects from UV-induced oxidative stress, chelates heavy metals, preserves from lipid peroxidation and structural changes caused by exposure to pollut- ants, and shields the skin from fi ne particles. Such properties make it an ideal antipollu- tion ingredient for a skin that looks luminous and healthy. The successful development of EPS-229, as a cosmetic active capable of shielding the skin from urban pollution, is a vibrant example of how biomimicry can lead to sustainable innovation. REFERENCES (1) J. Guézennec, X. Moppert, G. Gérard Raguénès, L. Richert, B. Costa, and C. Simon-Colin, Process Bio- chem., 46(1),16–22 (2011). (2) F. Rossi and R. De Philippis, Life (Basel)., 5(2), 1218–1238 (2015). (3) U. U. Nwodo, E. Green, and A. I. Okoh, Int. J. Mol. Sci., 13(11), 14002–14015 (2012). (4) C. Cassier-Chauvat and F. Chauvat, Int. J. Mol. Sci., 16(1), 871–886 (2014). (5) R. P. Rastogi, R. P. Sinha, S. H. Moh, T. K. Lee, S. Kottuparambil, Y. J. Kim, J. S. Rhee, E. M. Choi, M. T. Brown, D. P. Häder, and T. Han, J. Photochem. Photobiol. B., 141,154–169 (2014). (6) P. Kumar, L. Morawska, W. Birmili, P. Paasonen, M. Hu, M. Kulmala, R. M. Harrison, L. Norford, and R. Britter, Environ. Int., 66, 1–10 (2014). (7) L. Baumann, J. Invest. Dermatol., 125(4), xii–xiii (2005). (8) M. C. Dominguez, E. Sole, C. Goñi, and A. Ballabriga, Biol. Trace Elem. Res., 47(1–3), 57–67 (1995). (9) J. van Smeden, M. Janssens, G. S. Gooris, and J. A. Bouwstra, Biochem. Biophys. Acta., 1841(3), 295–313 (2014). (10) M. Mergener, C. R. Rhoden, and S. L. Amantéa, J. Pediatr. (Rio J)., 90(6), 632–636 (2014). (11) T. Hiraga, K. Ohyama, A. Hashigaya, T. Ishikawa, W. Muramoto, H. Kitagawa, N. Mizuno, and H. Teraoka, Vet J., 178(1), 109–114 (2008). (12) T. L. Pan, P. W. Wang, I. A. Aljuffali, C. T. Huang, C. W. Lee, and J. Y. Fang, J. Dermatol. Sci. 78(1), 51–60 (2015). (13) W. E. Roberts, J. Drugs Dermatol., 14(4), 337–341 (2015). Figure 6. EPS-229 helps remove PM2.5 particles from the skin surface.
J. Cosmet. Sci., 68, 133–136 ( January/February 2017) 133 Review of innovations to improve fragrance bloom, release, and retention on skin from surfactant-rich cosmetics VETHAMUTHU, M., LIRA, S., DIANTONIO, E., and FARES, H., Ashland Specialty Ingredients, Bridgewater NJ 08807. INTRODUCTION Fragrance molecules are small, highly volatile, and amphiphilic to different extents all of which makes them a challenging composition to effi ciently encapsulate, retain in micro- capsules, or a polymer matrix, and deposit them on a substrate such as skin or hair. This is particularly true when trying to do so from surfactant-rich cosmetic rinse-off product (1–3). Since volatility is an inherent fragrance attribute that leads to reduced sensory perception over time, a number of fragrance encapsulation technologies have been devel- oped to address this issue. These include fragrance-encapsulated polymeric microspheres (4), complex coacervation with various macromolecules (5), molecular inclusions into a host, such as cyclodextrin (6), and incorporation into solid lipid nanoparticles using ap- propriate lipids and surfactants (1,2,7). There are many challenges associated with these approaches, mainly due to the partial solubility in water of the many essential oil fra- grance components, causing hydrolytic instability in the microencapsulation process by interfacial reactions. In addition, side reactions could also lead to alteration of the encap- sulated “fragrance oils” which may limit its application in personal care products. This presentation will provide an overview of innovations and current challenges that address stability of fragrance encapsulates alone and in surfactant-rich formulations spe- cifi cally from leakage kinetics (integrity of microcapsule and its cargo). Next, technolo- gies that provide improved fragrance delivery and long-lasting fragrance perception on skin will be discussed. MATERIALS AND METHODS INSTRUMENTATION Analyses were performed on a 7890A GC combined with a 5975C Inert XL MSD with triple axis detector (Agilent Technologies). The gas chromatography mass spectrometry Address all correspondence to Martin Vethamuthu at MSVethamuthu@ashland.com.
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