BOOK REVIEWS PHARMACEUTICAl. ANALYSIS, edited by Takeru Higuchi and E. Broch- mann-Hanssen. Interscience Pub- lishers, Inc., New York 1, N.Y. 1961. 854 pages, indexed. Price $28.50. One is slightly misled by the title of this book for it is expected that the work will consist of an- alysis of the many ingredients and finished products which today com- prise "pharmaceuticals." Instead one finds thirteen selected subjects treated in as many chapters of widely varying page length. The shortest is that dealing with hydroxy- benzoic acids and their derivatives taking about 20 pages, while the chapter on alkaloids disproportion- ately utilizes about 230 pages. Each chapter is written by a top flight analyst either associated with a pharmaceutical manufacturing co.mpan. y. or attached to one of the universities. The work contributed appears to be of high caliber no errors in proofreading were noticed. But the book seems high priced. As a result its market will be pro- portionately reduced. The editors must be congratulated for a pains- taking job of style and usage uni- formity between the different au- thors. Yet, because of the limited number of contributions there are numerous voids. One would have liked to see methods of separation of the com- plex mixtures sold on prescription today--such items as syrups, sus- pensions, creams, lotions, ampoule solutions of tablets, for example. But, alas for this one still has to turn to Garratt, the official com- pendia and AOAC methods along with one's ingenuity. This book replaces nothing but it compliments and modernizes al- ready e.xisting texts or reference works m the area of "drug analysis."--M. G. DEN. ORGANIC CHEMISTRY Or BIVALENT Sul.ruR, Volume II. E. E. Reid, Chemical Publishing Co., Inc., New York 10, N.Y. 476 pages, in- dexed. Price $20. This second in a series of five volumes covers occurrence and prep- aration of sulfides, reactions of sulfides, physical properties of sul- fides, hydroxy- and halo-sulfides, mustard gas, sulfides with other substituents and physical properties of some substituted sulfides. Each chapter is heavily docu- mented with literature and patent references, as many as 1522 in the last chapter, for example. This will serve to complement the previously published volume and the others to come, making the work a monumental organic chem- istry of bivalent sulfur.--M. G. DEN. 319

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