EFFECTS OF AFTER-SHAVE LOTIONS ON SKIN I I.ORA 759 100 9O 8O 7O 6O 5O 40 3O 2O 10 Solutions- no perfume Commercial Lotions Soluhons- with xach I orophen e I I I I I 2 .'5 4 5 6 Time in hours Figure 10.--Face Plate Counts--Averages: Test solutions without perfume Com- mercial lotions Test solutions with hexachlorophene. The in vivo and in vitro procedures outlined here confirm each other and offer a choice of quick, convenient and reproducible methods for deter- mining the effects of perfume in alcoholic lotions. (Received June 22, 1964)
760 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS REFERENCES (1) Maruzzella, J. C., and Kirsch, N., Perfumery Essent. OilRecord, 54, 823 (1963•. (2) Sagatin, E., The Science and •4rt of Perfumery, McGraw Hill, New York, N.Y. (1945). (3) Drug Trade News, 38, No. 15, 4-12 (1963). (4) Cade, A. R., in Reddish, G. F., •tntiseptics, Disinfectants, Fungicides and SteriSzation, 2nd Ed., Lea and Febiger, Philadelphia, Pa. (1957), p. 355. (5) Cade, A. R., Ibid., p. 358. (6) Miller, R., Die Mikro-organismen der Mundh•le, (1892). (7) Freudenreich, E.,/Innales de Micrographie, 249 (1889). (8) Dyche-Teague, F. D., Perfumery Essent. Oil Record, 15, 6 (1924). (9) Bryant, J. J., Ibid., 15, 426 (1924). (10) Bryan, A. H., ,Im. Perfumer •4romat., 57, 33 (1951). (11) Hatfield, C. A., and Lockwood, J. S., Surgery, 13, 931-940 (1928). (12) Prombo, M.P., and Tilden, E. B., y. Dental Res., 29, 108-122 (1950). (13) Kliewe, H., and Huthmacher, E. R., Deut. •tpotheker-Z., 53, 952-955 (1938).
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