188 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS -. --%o •)

AMINO ACID METABOLITES IN DRY SKIN 189 z [•_ 30 20 10 a) • • Ser • Cit • o His Asp 2 3 TIME [•.K] 30 20 10 b) Set Cit Asp Orn L¾s 2 3 TIME Figure 3. The influence of experimentally induced hyperkeratosis on the free amino acid composition. a) = control b) = treated. Dry skin in winter. Of 77 subjects, the cheek skin was estimated as dry skin (A) in 25, accounting for 32% of the subjects. This suggests that skin gets chapped in winter in a considerable number of people (Table III). Amino acids and their metabolites were measured in 46 subjects, including 16 having dry skin (A Group), 22 with an inter- 30 o Pro AspThr Ser Cit Glu GI, Ala Val lie Leu Tyr Phe Orn Lys His Arg Figure 4. The free amino acid composition of human forearm stratum corneum 7 days after application of 3% LAS solution. Open bars = control solid bars = treated.