ELECTROSPUN PVA FIBER MATS AS EXTRACT CARRIERS 241 (NANOTEC), Thailand (grant number: BR0108). O.S. acknowledges a doctoral schol­ arship from the Thailand Graduate Institute of Science and Technology (TGIST) (TG- 5 5-09-49-069D). REFERENCES (1) B. M. Sundaram, C. Gopalakrishnan, S. Subramanian, D. Shankaranarayanun, and L. Kameswaran, Antimicrobial activities of Garcinia mangostana, Planta Med., 48, 59-60 (1983). (2) P. Moongkarndi, N. Kosem, 0. Luanratana, S. Jongsomboonkusol, and N. Pongpan, Antiproliferative activity of Thai medicinal plant extracts on human breast adenocarcinoma cell line, Fitoterapia, 75, 375-377 (2004). (3) P. Moongkarndi, N. Kosem, S. Kaslungka, 0. Luanratana, N. Pongpan, and N. Neungton, Antipro­ liferation, antioxidation and induction of apoptosis by Garcinia mangostana (mangosteen) on SKBR3 human breast cancer cell line,]. Ethnopharmacol., 90, 161-166 (2004). (4) W. Weecharangsan, P. Opanasopit, M. Sukma, T. Ngawhirunpat, U. Sotanaphun, and P. Siripong, Antioxidative and neuroprotective activities of extracts from the fruit hull of mangosteen (Garcinia mangostana Linn.), Med. Prine. Pract., 15, 281-287 (2006). (5) H. A. Jung, B. N. Su, W. J. Keller, R. G. Mehta, and A. D. Kinghorn, Antioxidant xanthones from pericap of Garcinia mangostana (mangosteen),]. Agric. Food Chem., 54, 2077-2082 (2006). (6) P. Williams, M. Ongsakul, J. Proudfoot, K. Croft, and L. Beilin, Mangostin inhibits the oxidative modification of human low density lipoprotein, Free Radie. Res., 23, 175-184 (1995). (7) N. Chairungsrilerd, K. Furukawa, T. Ohta, S. Nozoe, and Y. Ohizumi, Histaminergic and serotonergic receptor blocking substances from the medicinal plant Garcinia mangostana, Planta Med., 62, 471-472 (1996). (8) K. Nakatani, M. Atsumi, T. Arakawa, K. Oosawa, S. Shimura, N. Nakahata, and Y. Ohizumi, Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant, Biol. Pharm. Bull., 25, 1137-1141 (2002). (9) D. Shankaranarayan, C. Gopalakrishnan, and L. Kameswaran, Pharmacological profile of mangostin and its derivatives, Arch. Int. Pharmacodyn., 239, 257-269 (1979). (10) C. Gopalakrishnan, D. Shankaranarayanan, L. Kameswaran, and S. K. Nazimudeen, Effect of mangos­ tin, a xanthone from Garcinia mangostana in immunopathological and inflammatory reactions, Ind.]. Exp. Biol., 18, 843-846 (1980). (11) N. R. Farnsworth and N. Bunyapraphatsara, Thai Medicinal Plant: Recommended for Primary Health Care System (Prachachon Company, Bangkok, 1992), pp. 25-50. (12) J. Y. Lu, C. Normal, K. A. Abboud, and A. Ison, Crystal engineering of an inclusion coordination polymer with cationic pocket-like structure and its property to form metal-organic nanofibers, Inorg. Chem. Commun., 4, 459-461 (2001). (13) J. Doshi and D. H. Reneker, Electrospinning process and applications of electrospun fibers,]. Elec­ trostat., 35, 151-160 (1995). (14) C. Zhang, X. Yuan, L. Wu, Y. Han, and J. Sheng, Study on morphology of electrospun poly(vinyl alcohol) mats, Eur. Polym. ]., 41, 423-432 (2005). (15) Y. M. Shim, M. M. Hohman, M. P. Brenner, and G. C. Rutledge, Experimental characterization of electrospinning: The electrically forced jet and instabilities, Polymer, 42, 9955-9967 (2001). (16) S. A. Theron, E. Zussman, and A. L. Yarin, Experimental investigation of the governing parameters in the electrospinning of polymer solutions, Polymer, 45, 2017-2030 (2004). (17) B. Ding, H. Y. Kim, S. C. Lee, C. L. Shao, D. R. Lee, S. J. Park, G. B. Kwag, and K. J. Choi, Preparation and characterization of a nanoscale poly(vinyl alcohol) fibre aggregate produced by an electrospinning method,]. Polym. Sci. Polym. Phys., 40, 1261-1268 (2002). (18) L. L. Wu, X. Y. Yuan, and J. Sheng, Immobilization of cellulose in nanofibrous PVA membranes by electrospinning,J. Membr. Sci., 250, 167-173 (2005). (19) J. S. Choi, S. W. Lee, L. Jeong, S. H. Bae, B. C. Min, J. H. Youk, and W. H. Park, Effect of organo­ soluble salts on the nanofibrous structure of electrospun poly(3-hydroxybutyrate-co-3- hydroxyvalerate), Int.]. Biol. Macromol., 34, 249-256 (2004). (20) K. Kim, Y. K. Luu, C. Chang, D. F. Fang, B. S. Hsiao, B. Chu, and M. Hadjiargyrou, Incorporation and controlled release of a hydrophilic antibiotic using poly(lactide-co-glycolide)-based electrospun nanofibrous scaffolds,]. Control. Release, 98, 47-56 (2004).

242 JOURNAL OF COSMETIC SCIENCE (21) J. Zeng, X. Xu, X. Chen, Q. Liang, X. Bian, L. Yang, and X. Jing, Biodegradable electrospun fibers for drug delivery,]. Control. Release, 92, 227-231 (2003). (22) G. Verreck, I. Chun, J. Peeters, J. Rosenblatt, and M. E. Brewster, Preparation and characterization of nanofibers containing amorphous drug dispersions generated by electrostatic spinning, Pharm. Res., 20, 810-817 (2003). (23) G. Verreck, I. Chun,]. Rosenblatt,]. Peeters, A. van Dijck,J. Mensch, M. Noppe, and M. E. Brewster, Incorporation of drugs in an amorphous state into electrospun nanofibers composed of a water­ insoluble, non-biodegradable polymer,]. Control. Release, 92, 349-360 (2003). (24) P. Taepaiboon, U. Rungsardthong, and P. Supaphol, Drug-loaded electrospun mats of poly(vinyl alcohol) fibers and their release characteristics of four model drugs, Nanotechnology, 17, 2317-2329 (2006) (25) A. Koski, K. Yim, and S. Shivkumar, Effect of molecular weight on fibrous PVA produced by electrospinning, Mater. Lett., 58, 493-497 (2004). (26) S. J. Kim, S. J. Park, K. H. An, N. G Kim, and S. I. Kim, Water behavior of poly(vinyl alcohol)/ poly(vinylpyrrolidone) interpenetrating polymer network hydrogels,]. Appl. Polym. Sci., 89, 24-27 (2003). (27) W. K. Son, J. H. Youk, T. S. Lee and, W. H. Park, Effect of pH on electrospinning of poly(vinyl alcohol), Mater. Lett., 59, 1571-1575 (2005). (28) M. S. Blois, Antioxidant determination by the use of a stable free radical, Nature, 181, 1199-1200 (1958). (29) R. Rujiravanit, S. Kruaykitanon, A. M. Jamieson, and S. Tokura, Preparation of crosslinked chitosan/ silk fibroin blend films for drug delivery system, Macromol. Biosci., 3, 604-611 (2003). (30) J. Zeng, A. Aigner, F. Czubayko, T. Kissel, J. H. Wendorff, and A. Greiner, Poly(vinyl alcohol) nanofibers by electrospinning as a protein delivery system and the retardation of enzyme release by additional polymer coatings, Biomacromolecules, 6, 1484-1488 (2005).