142 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS Figure 5. 16 MPD: General morphology. Hematoxylin and eosin stain. A: SPF-7 sunscreen (magnification X295). The hyperplastic epidermis is characterized by thick downgrowths, loss of order, atypia, and numerous sunburn cells (•). Foci of parakeratosis are present (*). B: SPF-7 sunscreen (magnification X 115). Inflammatory infiltrates are present in the upper dermis, cysts have proliferated to 3-4 rows, and the granulomatous reaction is severe (--•-). Overall, the skin is greatly thickened.
BROAD-SPECTRUM SUNSCREENS 143 Figure 5. Continued. C: SPF-16 sunscron (magnification X295). The thickened epidermis displays atypia, loss of order, dyshesion, and sunburn cells ( • ). D: SPF-16 sunscron (magnification X 115). Cysts have proliferat• to 2-3 rows. lnfi•mation andthe granulomatous reaction are not as severe as with the SPF-7 sunscreen.
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