224 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS . o Figure 1. (a) Low magnification overview of water-washed tissue displaying the separation between dis- juncture and compactum regions of SC. Disjuncture is characterized by the absence of interlayer desmo- somes (arrowheads) (! ! 000 x). (b) Lipids covering the outermost corneocytes of disjunctum (arrowheads) in control tissue show few multiple layers of ordered lameliar structures (128,000x).

SURFACTANT-SKIN INTERACTIONS 225 Figure 1. (c) Water-washed control tissue showing the presence of interlayer desmosomes (arrowheads) in the outer regions of SC and absence of disjuncture (24,000x). (d) Multilayered lipid lamellae (arrows) enveloping the outer layers of corneocytes and desmosomes (arrowheads) were seen in those regions of control tissue that lacked disjuncture (128,000x).

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