MICRO-ORGANISMS IN PHARMACEUTICALS AND COSMETICS PREPARATIONS 425 wards. The control of pharmaceutical preparations during the interval between preparation and administration to the patient is often imperfect, and is a fruitful area for collaboration between the pharmacist and the clinical microbiologist. (Received: 7th July 1971) REFERENCES (lO) (11) (12) (13) 04) (16) (17) (19) (20) (1) Olsen, H. An epidemiological study of hospital infection with Flavobacterium meningo- septicurn. Danish Med. Bull. 14 6 (1967) (2) Noble, W. C. and Savin, J. A. Steroid cream contaminated with Pseudomonas aeruginosa. Lancet i 347 (1966). (3) Bassett, D.C. J., Stokes, K. J. and Thomas, W. R. G. Wound infection due to Pseudomonas multivorans. A water-borne contaminant of disinfectant solutions. Lancet i 1188 (1970). (4) Mitchell, R. G. and Hayward, A. C. Post-operative urinary-tract infections caused by contaminated irrigating fluid. Lancet i 793 (1966). (5) Hardy, P. C., Ederer, G. M. and Matsen, J. M. Contamination of commercially packaged urinary catheter kits with the pseudomonad EO-1. New Engl. J. Med. 282 33 (1970). (6) Mertz, J. J., Scharer, L. and McClement, J. H. A hospital outbreak of klebsiel a pneumonia from inhalation therapy with contaminated aerosol solutions. Am. Rev. Respirat. Diseases 95 454 (1967). (7) Phillips, I. Post-operative respiratory-tract infection with Pseudomonas aeruginosa due to contaminated lignocaine jelly. Lancet i 903 (1966). (8) Theodore, F. H. and Feinstein, R. R. Practical suggestions for the preparation and main- tenance of sterile ophthalmic solutions. Am. J. OphthalmoL 35 656 (1952). (9) Ayliffe, G. A. J., Barry, D. R., Lowbury, E. J. L., Roper-Hall, M. J. and Walker, W. M. Post-operative infection with Pseudomonas aeruginosa in an eye hospital. Lancet i 1113 (1966). Kallings, L. O., Ringertz, O., Silverstolpe, L. and Enerfeldt, F. Microbiological con- tamination of medical preparations. Acta Pharm. Suecica 3 219 (1966). Forkher, C. E. Pseudomonas aeruginosa infections 59 (1960). (Grune & Stratton, New York). Gerke, J. R. and Magliocco, M. V. Experimental Pseudomonas aeruginosa infection of the mouse cornea. Infection and Immunity 3 209 (1971). Crompton, D. O., Anderson, K. F. and Kennare, M. A. Experimental infection of the rabbit anterior chamber. Trans. Ophthalmol. $oc. Australia 22 81 (1962). Neter, E. and Weintraub, D. H. The epidemiological study of Pseudomonas aeruginosa (Bacillus pyocyanea) in premature infants in the presence and absence of infection. J. Pediatrics 46 280 (1955). (15) Wassermann, M. Ueber eine Epidemie-artig aufgetretene septische Nabel-Infektion Neugeborener ein Beweis fiir pathogenetiche Wirksarnkeit des Bacillus pyocyaneus beim Menschen. Virchows Arch. Pathal. Anat. Physiol. Klin. Med. 165 342 (1901). Cooke, E. M., Shooter, R. A., O'Farrell, S. M. and Martin, D. R. Faecal carriage of Pseudo- monas aeruginosa by newborn babies. Lancet ii 1045 (1970). Victorin, L. An epidemic of otitis in newborns due to infection with Pseudomonas aeru- ginosa. Acta Paediat. Scan& 56 344 (1967). McCormack, R. C. and Kunin, C. M. Control of a single source nursery epidemic due to Serfaria marcescens. Pediatrics 37 750 (1966). Plotkin, S. A. and McKitrick, J. C. Nosocomial meningitis of the newborn caused by a fiavobacterium. J. Amer. Med. Assoc. 198 662 (1966). Morse, L. J., Williams, H. L., Grenn, F. P., Eldridge, E. E. and Rotta, J. R. Septicaemia due to Klebsiella pneumoniae originating from hand-cream dispenser. New Engl. J. Med. 277 472 (1967). (21) Lang, D. J., Kurtz, L. J., Martin, A. R., Schroeder, E. R. and Thomson, L. A. Carmine as a source of nosocomial salmonellosis. New Engl. J. Med. 276 829 (1967). (22) Elkoff, T. C. Nosocomial salmonellosis due to carmine. Ann. Internal Med. 66 813 (1967). (23) Steinbach, H. L., Rousseau, R., McCormack, K. R. and Jawetz, E. Transmission of enteric pathogens by barium enema. J. Am. Med. Assoc. 174 1207 (1960). (24) Darrell, J. H. and Wahba, A. H. Pyocine-typing of hospital strains of Pseudomonas pyo- cyanea. J. Clin. Pathal. 17 236 (1964).
426 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS (27) (28) (29) (30) (31) (32) (33) (34) (35) (36) (37) (38) (39) (40) (41) (42) (43) (44) (46) (47) (48) (49) (50) (51) (25) Shooter, R. A., Walker, K. A., Williams, V. R., Horgan, G. M., Parker, M. T., Asheshov, E. H. and Bullimore, J. F. Faecal carriage of Pseudomonas aeruginosa in hospital patients possible spread from patient to patient. Lancet ii 1331 (1966). (26) Shooter, R. A., Cooke, E. M., Gaya, H., Kumar, P., Patel, N., Parker, M. T., Thom, B. T. and France, D. R. Food and medicaments as possible sources of hospital strains of Pseudo- monas aeruginosa. Lancet i 1227 (1969). Hooper, W. L. The nature and extent of the microbial contamination of pharmaceutical preparations in hospital. Symposium on 'Microbial control', London (29 September 1971). Buck, A. C. and Cooke, E. M. The fate of ingested Pseudomonas aeruginosa in normal persons. J. Med. Microbiol. 2 521 (1969). Gaya, H., Adnitt, P. I. and Turner, P. Changes in the gut flora after cephalexin treatment. Brit. Med. J. 2 624 (1970). Wilson, G. S. and Miles, A. A. in Topley, W. W. C. and Wilson, G. S. Principles of Bac- teriology and Immunity, 5th edn, 1922 (1964) (Edward Arnold, London). Kuntz, L. J. and Ouchterlony, O. T. G. Salmonellosis originating in a hospital a newly recognized source of infection. New Engl. J. Med. 253 761 (1955). McCall, C. E., Collins, R. N., Jones, D. B., Kauffmann, A. F. and Brachman, P.S. An inter- state outbreak of salmonellosis traced to a contaminated food supplement. Am. J. Epidemiol. 84 32 (1966). Stoodley, B. J. and Thom, B. T. Observations on the intestinal carriage of Pseudomonas aeruginosa. J. Med. Microbiol. 3 367 (1970). Burkholder, W. H. Sour skin, a bacterial rot of onion bulbs. Phytopathology 40 115 (1950). Morris, M. B. and Roberts, J. B. A group of pseudomonads able to synthesize poly-13- hydroxybutyric acid. Nature (London) 193 1538 (1959). Philips, I., Eikyn, S., Curtis, M. A. and Snell, J. J. S. Pseudomonas cepacia (multivorans) septicaemia in an intensive care unit. Lancet i 375 (1971). Speller, D.C. E., Stephens, M. E. and Viant, A. C. Hospital infection with Pseudomonas cepacia. Lancet i 798 (1971). Baumann, P., Doudoroff, M. and Stanier, R. Y. A study of the moraxella group. II. Oxidase-negative species (genus Acinetobacter). J. Bacteriol. 95 1520 (1968). Taplin, D., Rebell, G. and Zias, N. The human skin as a source of Mima-Herellea infections. J. Am. Med. Assoc. 186 952 (1963). Adair, F. W., Geftic, S. G. and Gelzer, J. Resistance of Pseudornonas to quaternary ammo- nium compounds. I. Growth in benzalkonium chloride solution. Appl. Microbiol. 18 299 (1969). Lowbury, E. J. L. and Fox, J. The influence of atmospheric drying on the survival of wound flora. J. Hyg. Cambridge 51 203 (1953). Burdon, D. W. and Whitby, J. L. Contamination of hospital disinfectants with Pseudomonas species. Brit. Med. J. 2 153 (1967). Bassett, D. C. J. The effect of pH on the multiplication of a pseudomonad in chlorhexidine and cetrimide. J. Clin. Pathol. 24 706 (1971). U.S. Department of Health, Education and Welfare. Nosocomial bacteraemias associated with intravenous fluid therapy--U.S.A. Morbidity and Mortality Weekly Report. Special supplement to 20 (No. 9, 12 March) (1971). (45) U.S. Department of Health, Education and Welfare. Follow-up on septicaemias associated with contaminated Abbott intravenous fluids---U.S.A. MorbMity and Mortality Weekly Report, 20 91 (No. 10, 26 March) (1971). Morse, L. J. and Schonbeck, L. E. Hand lotions--a potential nosocomial hazard. New Engl. J. Meal. 278 376 (1968). Ayliffe, G. A. J., Barrowcliff, D. F. and Lowbury, E. J. L. Contamination of disinfectants. Brit. Med. J. I 505 (1969). Knights, H. T. and Harvey, J. Hand creams containing hexachlorophene and cross infection with Gram-negative bacteria. New Zealand Med. J. 63 653 (1964). Palmer, P. H. and McCracken, L. M. Contaminated antiseptic solutions. Lancet il 776 (1970). Simmons, N. A. and Gardner, D. A. Bacterial contamination of a phenolic disinfectant. Brit. Med. J. 2 668 (1969). Bassett, D.C. J. Causes and prevention of sepsis due to Gram-negative bacteria common- source outbreaks. Proc. Roy. Soc. Med. 64 980 (1971).
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