172 JOURNAL OF COSMETIC SCIENCE
(9) Andersen FA, Bergfeld WF, Belsito DV, et al. Final amended safety assessment of hydroquinone as used
in cosmetics. Int J Toxicol. 2010 29(6)(suppl):274S-2787.
(10) Wang J, Chen Z, Lu Y, et al. Soluble Pearl Extract provides effective skin lightening by antagonizing
endothelin. J Cosmet Dermatol. 2021 20(8):2531-2537.
(11) Yang YL, Chang CH, Huang CC, Liu HW. Anti-inflammation and anti-apoptosis effects of pearl extract
gel on UVB irradiation HaCaT cells. Bio Med Mater Eng. 2015 26(suppl 1):S139-S145.
(12) Scott GA, Cassidy L. Rac1 mediates dendrite formation in response to melanocyte stimulating hormone
and ultraviolet light in a murine melanoma model. J Invest Dermatol. 1998 111(2):243-250.
(13) Alzahofi N, Welz T, Robinson CL, et al. 27a coordinates actin-dependent transport by controlling
organelle-associated motors and track assembly proteins. Nat Commun. 2020 11:3495.
(14) Netcharoensirisuk P, Umehara K, De-Eknamkul W, Chaotham C. Cajanin suppresses melanin synthesis
through modulating MITF in human melanin-producing cells. Molecules. 2021 26(19):6040.
(15) C. Chiaverini, L. Beuret, E. Flori, R. Busca, P. Abbe, K. Bille, P. Bahadoran, J. P. Ortonne, C. Bertolotto
and R. Ballotti, Microphthalmia-associated transcription factor regulates RAB27A gene expression and
controls melanosome transport. J. Biol. Chem., 283, 12635-12642(2008).
(16) Mamat N, Dou J, Lu X, Eblimit A, Haji Akber A. Isochlorogenic acid A promotes melanin synthesis in
B16 cell through the β-catenin signal pathway. Acta Biochim Biophys Sin (Shanghai). 2017 49(9):800-807.
(17) Ko SC, Lee SH. Protocatechuic aldehyde inhibits α-MSH-induced melanogenesis in B16F10 melanoma
cells via PKA/CREB-associated MITF downregulation. Int J Mol Sci. 2021 22(8).
(18) Guo B, Qi M, Huang S, et al. Cadherin-12 regulates neurite outgrowth through the PKA/Rac1/Cdc42
pathway in cortical neurons. Front Cell Dev Biol. 2021 9:768970.
(19) Cianfrocca R, Rosanò L, Tocci P, et al. Blocking endothelin-1-receptor/β-catenin circuit sensitizes to
chemotherapy in colorectal cancer. Cell Death Differ. 2017 24(10):1811-1820.
(9) Andersen FA, Bergfeld WF, Belsito DV, et al. Final amended safety assessment of hydroquinone as used
in cosmetics. Int J Toxicol. 2010 29(6)(suppl):274S-2787.
(10) Wang J, Chen Z, Lu Y, et al. Soluble Pearl Extract provides effective skin lightening by antagonizing
endothelin. J Cosmet Dermatol. 2021 20(8):2531-2537.
(11) Yang YL, Chang CH, Huang CC, Liu HW. Anti-inflammation and anti-apoptosis effects of pearl extract
gel on UVB irradiation HaCaT cells. Bio Med Mater Eng. 2015 26(suppl 1):S139-S145.
(12) Scott GA, Cassidy L. Rac1 mediates dendrite formation in response to melanocyte stimulating hormone
and ultraviolet light in a murine melanoma model. J Invest Dermatol. 1998 111(2):243-250.
(13) Alzahofi N, Welz T, Robinson CL, et al. 27a coordinates actin-dependent transport by controlling
organelle-associated motors and track assembly proteins. Nat Commun. 2020 11:3495.
(14) Netcharoensirisuk P, Umehara K, De-Eknamkul W, Chaotham C. Cajanin suppresses melanin synthesis
through modulating MITF in human melanin-producing cells. Molecules. 2021 26(19):6040.
(15) C. Chiaverini, L. Beuret, E. Flori, R. Busca, P. Abbe, K. Bille, P. Bahadoran, J. P. Ortonne, C. Bertolotto
and R. Ballotti, Microphthalmia-associated transcription factor regulates RAB27A gene expression and
controls melanosome transport. J. Biol. Chem., 283, 12635-12642(2008).
(16) Mamat N, Dou J, Lu X, Eblimit A, Haji Akber A. Isochlorogenic acid A promotes melanin synthesis in
B16 cell through the β-catenin signal pathway. Acta Biochim Biophys Sin (Shanghai). 2017 49(9):800-807.
(17) Ko SC, Lee SH. Protocatechuic aldehyde inhibits α-MSH-induced melanogenesis in B16F10 melanoma
cells via PKA/CREB-associated MITF downregulation. Int J Mol Sci. 2021 22(8).
(18) Guo B, Qi M, Huang S, et al. Cadherin-12 regulates neurite outgrowth through the PKA/Rac1/Cdc42
pathway in cortical neurons. Front Cell Dev Biol. 2021 9:768970.
(19) Cianfrocca R, Rosanò L, Tocci P, et al. Blocking endothelin-1-receptor/β-catenin circuit sensitizes to
chemotherapy in colorectal cancer. Cell Death Differ. 2017 24(10):1811-1820.









































































