198 JOURNAL OF COSMETIC SCIENCE
2. Yarova G. et al. “Delivering Nutrient Benefits from Cleansers to the Skin Through
Enhanced Ceramide Production and Continues Nourishment” 2021 AAD e-poster.
ACKNOWLEDMENTS
The authors thank Hannah Avery and Alice Kirby of Meditech Media, UK for providing
medical writing support.
CONFLICT OF INTEREST
The authors declare that no competing interest exist.
AUTHORS ORCID IDS
Galina Yarova – 0000-0002-4105-1504
William F. Lathrop – 0000-0001-6434-3975
Andrew E. Mayes – 0000-0003-4060-0660
Stacy Hawkins – 0000-0002-8791-9567
Brian Dobkowski – 0000-0003-3474-1811
Bivash R. Dasgupta -0000-0001-7932-3483
John S. Bajor – 0000-0003-4614-6956
REFERENCES
(1) Danso MO, Berkers T, Mieremet A, Hausil F, Bouwstra JA. An ex vivo human skin model for studying
skin barrier repair. Exp Dermatol. 2015 24(1):48–54.
(2) van Smeden J, Bouwstra JA. Stratum corneum lipids: their role for the skin barrier function in healthy
subjects and atopic dermatitis patients. Curr Probl Dermatol. 2016 49:8–26.
(3) Madison KC, Swartzendruber DC, Wertz PW, Downing DT. Presence of intact intercellular lipid
lamellae in the upper layers of the stratum corneum. J Invest Dermatol. 1987 88(6):714–718.
(4) Berkers T, van Dijk L, Absalah S, van Smeden J, Bouwstra JA. Topically applied fatty acids are
elongated before incorporation in the stratum corneum lipid matrix in compromised skin. Exp Dermatol.
2017 26(1):36–43.
(5) Knox S, O’Boyle NM. Skin lipids in health and disease: a review. Chem Phys Lipids. 2021 236:105055.
(6) Cha HJ, He C, Zhao H, Dong Y, An IS, An S. Intercellular and intracellular functions of ceramides and
their metabolites in skin (Review) [review]. Int J Mol Med. 2016 38(1):16–22.
(7) Damien F, Boncheva M. The extent of orthorhombic lipid phases in the stratum corneum determines the
barrier efficiency of human skin in vivo. J Invest Dermatol. 2010 130(2):611–614.
(8) J.A. Bouwstra, P.L. Honeywell-Nguyen, G.S. Gooris, M. Ponec, Structure of the skin barrier and its
modulation by vesicular formulations, Prog Lipid Res, 42, 1–36, (2003).
(9) Bouwstra JA, Honeywell-Nguyen PL, Gooris GS, Ponec M. Structure of the skin barrier and its
modulation by vesicular formulations. Prog Lipid Res. 2003 42(1):1–36.
(10) van Smeden J, Janssens M, Kaye EC, et al. The importance of free fatty acid chain length for the skin
barrier function in atopic eczema patients. Exp Dermatol. 2014 23(1):45–52.
2. Yarova G. et al. “Delivering Nutrient Benefits from Cleansers to the Skin Through
Enhanced Ceramide Production and Continues Nourishment” 2021 AAD e-poster.
ACKNOWLEDMENTS
The authors thank Hannah Avery and Alice Kirby of Meditech Media, UK for providing
medical writing support.
CONFLICT OF INTEREST
The authors declare that no competing interest exist.
AUTHORS ORCID IDS
Galina Yarova – 0000-0002-4105-1504
William F. Lathrop – 0000-0001-6434-3975
Andrew E. Mayes – 0000-0003-4060-0660
Stacy Hawkins – 0000-0002-8791-9567
Brian Dobkowski – 0000-0003-3474-1811
Bivash R. Dasgupta -0000-0001-7932-3483
John S. Bajor – 0000-0003-4614-6956
REFERENCES
(1) Danso MO, Berkers T, Mieremet A, Hausil F, Bouwstra JA. An ex vivo human skin model for studying
skin barrier repair. Exp Dermatol. 2015 24(1):48–54.
(2) van Smeden J, Bouwstra JA. Stratum corneum lipids: their role for the skin barrier function in healthy
subjects and atopic dermatitis patients. Curr Probl Dermatol. 2016 49:8–26.
(3) Madison KC, Swartzendruber DC, Wertz PW, Downing DT. Presence of intact intercellular lipid
lamellae in the upper layers of the stratum corneum. J Invest Dermatol. 1987 88(6):714–718.
(4) Berkers T, van Dijk L, Absalah S, van Smeden J, Bouwstra JA. Topically applied fatty acids are
elongated before incorporation in the stratum corneum lipid matrix in compromised skin. Exp Dermatol.
2017 26(1):36–43.
(5) Knox S, O’Boyle NM. Skin lipids in health and disease: a review. Chem Phys Lipids. 2021 236:105055.
(6) Cha HJ, He C, Zhao H, Dong Y, An IS, An S. Intercellular and intracellular functions of ceramides and
their metabolites in skin (Review) [review]. Int J Mol Med. 2016 38(1):16–22.
(7) Damien F, Boncheva M. The extent of orthorhombic lipid phases in the stratum corneum determines the
barrier efficiency of human skin in vivo. J Invest Dermatol. 2010 130(2):611–614.
(8) J.A. Bouwstra, P.L. Honeywell-Nguyen, G.S. Gooris, M. Ponec, Structure of the skin barrier and its
modulation by vesicular formulations, Prog Lipid Res, 42, 1–36, (2003).
(9) Bouwstra JA, Honeywell-Nguyen PL, Gooris GS, Ponec M. Structure of the skin barrier and its
modulation by vesicular formulations. Prog Lipid Res. 2003 42(1):1–36.
(10) van Smeden J, Janssens M, Kaye EC, et al. The importance of free fatty acid chain length for the skin
barrier function in atopic eczema patients. Exp Dermatol. 2014 23(1):45–52.








































































