438 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS Particle size oils effects, occlusion, skin, 345 Perfumes allergies prevention, using anti- irritants, 415 odors evaluations, perceived fragrance complexity, humans, 253 evaluations, psychophysical, 91 Petrolatum effects transepidermal, water loss, humans, 333 moisture transepidermal, loss prevention, evaluation, equipment, 181 occlusion skin, measurement, using transepidermal water loss, humans, 345 Polysorbate 20 emulsions oil-in-water, formulations, low surfactant concentration, 167 Powders methodology occlusion, skin, measured using transepidermal water loss, humans, 345 Preservatives cosmetics evaluations, linear regression method, 321 parabens emulsions. selection, 25 Proteins hair: effects, chemicals, hair preparations, 401 Psychology odors perfumes, psychophysical measurement, 91 2-Pyridinesulfonic acid l-oxide chromatography, liquid shampoos, 73 2-Pyridinesulfonic acid chromatography, liquid shampoos, 73 2-Pyridinethiol chromatography, liquid shampoos, 73 Raw materials cosmetics analysis, nitrites and nitrosamines, 127 sodium nitrite colorimetry, 385 Shampoos 2,2'-dithiobis-pyridine- l, 1 '-dioxide chromatography, liquid, 73 gels formulations, nonirritant, 415 preservatives evaluations, linear regression method, 321 Side effects, see Toxicity Silicones antifoams transient, effects, foam stability, 105 antiperspirants sticks, formulations, 137 Skin moisture effects, oil films, measurement, using transepidermal water loss, humans, 345 loss, measurement, transepidermal, 369 transepidermal, loss, from and dry and normal skin, humans, 333 stratum corneum topology, relief structure, 213 Sodium nitrite colorimetry raw materials, 385 Solubility parabens preservatives, emulsions, use in selection, 25 surface active agents use, o/w emulsification, 167 Solutions, ophthalmic tetrahydrozoline toxicity, eye irritation studies, humans, 67 Sorbitan monolaurate emulsions oil- in-water, formulations, low surfactant concentration, 167 Span 20, see Sorbitan monolaurate Squalane effects skin, biosynthesis, rabbits, 263 Stability dyes hair, oxidative reactions with p- a•ninophenols, 191 foams effects, transient antifoams, 105 hydrophilic ointment structure, DAB 7 formulations, 9 Stearyl alcohol, see Alcohols, stearyl Sticks antiperspirants formulations, stearyl alcohol-volatile silcones, 137 Structure emulsions properties, 3 phase, 309 hydrophilic ointment German Pharmacopeia, DAB 7, 9 Structure-activity relationships alcohols sulfates, ether sulfates and ethoxylates, rat skin absorption, effects, chain length, 157 surface active agents effects, keratin penetration, 41 Sulfur and derivatives odors, oral, instrumental evaluation using bacteria, 241 Sunscreen agents effects protection factor, hmnans, 81 Surface active agents absorption keratin, structure effects, 41 antifoams transient. effects, discussion, 105 effects antiperspirants, aluminum salts, hmnans, 357 polysorbate 20 emulsions, o/w, low surfactant concentration, 167 sorbitan monolaurate emulsions, o/w, low surfactant concentration, 167 Temperature effects moisture, transepidermal, loss, measurement, equipment, 181 Tetrahydrozoline solutions, ophthalmic toxicity, eye irritation, humans, 67 Therapeutic efficacy, see Drugs, clinical effectiveness Therapeutic equivalent, see Drugs, clinical effectiveness

SUBJECT INDEX 439 Thioglycolates hair preparations effects, proteins of whole hair, cuticle and cortex, 401 Topical preparations absorption methodology, guinea pig, comparison, fetal hog skin, 375 petrolatum effects, transepidermal water loss, humans, 333 Toxicity see also Drugs, adverse reactions cosmetics prevention, anti-irritants, 415 decane effects, skin biosynthesis, rabbits, 263 surface active agents effects, keratin, 41 tetrahydrozoline eye, irritation, humans, 67 Toxicity, environmental copper hair, green coloration, 1 Tween 20, see Polysorbate 20 Vasoconstricting agents tetrahydrozoline toxicity, eye irritation studies, humans, 67 Water toxicity, environmental hair, green discoloration due to copper content, 1 Wetting agents, see Surface active agents ¾1ang-ylang oil odors evaluations, perceived fragrance complexity, humans, 253 The Author and Subject indexes were prepared by the American Society of Hospital Pharmacists through its computerized IPA Information System.