INFLUENCE OF DEPLETION ON PERCUTANEOUS ABSORPTION 247 10 4O 2O • I I I I I I I I I I .0001 .001 .01 .1 1 10 VOLUME (ml) Figure 11. Effect of value of Ki/K_ I on maximum penetration rate for various donor volumes. K = 0.6 hr -i. z B TIME 12 (HR) 18 B Figure 12. Amount on the surface (fraction of applied dose) as a function of time at different values of Ki/K_ I. Donor volume = 0.0032 mi. (A) 5. (B) 10. (C) 20. (D) 40.
248 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS z m z z B 0 4 8 12 16 20 TIME (HR) Figure 13. Amount in the membrane (fraction of the applied dose) as a function of time. Details as for Figure 12. 0 4 8 12 15 20 TIME (HR) Figure 14. Amount penetrated (fraction of applied dose) as a function of time. Details as for Figure 12.
Previous Page Next Page 
Purchased for the exclusive use of nofirst nolast (unknown)
From: SCC Media Library & Resource Center (library.scconline.org)