150 JOURNAL OF COSMETIC SCIENCE (5) H. Takahashi and P. G. Parsons, Rapid and reversible inhibition of tyrosinase activity by glucosidase inhibitors in human melanoma cells,]. Invest. Dermatol., 98(4), 481-487 (1992). (6) G. Imokawa, Analysis of carbohydrate properties essential for melanogenesis in tyrosinases of cultured malignant melanoma cells by differential carbohydrate processing inhibition,]. Invest. Dermatol., 95(1), 39-49 (1990). (7) G. E. Costin, M. Trif, N. Nichita, R. A. Dwek, and S. M. Petrescu, pH-sensitive liposomes are efficient carries for endoplasmic reticulum-targeted drugs in mouse melanoma cells, Biochem. Biophys. Res. Commun., 293, 918-923 (2002). (8) B. W. Barry, Drug delivery routes in skin: A novel approach, ADDR, 54, S31-S40 (2002). (9) A. Ohashi, Y. Funasaka, M. Ueda, and M. Ichihashi, c-KIT receptor expression in cutaneous malignant melanoma and benign melanocytic naevi, Melanoma Res., 6, 25-30 (1996). (10) T. Mossman, Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays,]. Immunol. Meth., 65, 55-63 (1983). (11) G. E. Costin, J.C. Valencia, W. D. Vieira, M. L. Lamoreux, and V. J. Hearing, Tyrosinase processing and intracellular trafficking is disrupted in mouse primary melanocytes carrying the underwhite (uw) mutation: A model for oculocutaneous albunism (OCA) type 4,j. Cell Sci., 116, 3203-3212 (2003). (12) S. Simoes, J. N. Moreira, C. Fonseca, N. Di.izgtines, and M. C. Pedroso de Lima, On the formulation of pH-sensitive liposomes with long circulation times, ADDR, 56, 947-965 (2004). (13) A Varki, Biological roles of oligosaccharides: All of the theories are correct, Glycobiology, 3, 97-130 (1993). (14) K. Kono, T. Igawa, and T. Takagishi, Cytoplasmic delivery of calcein mediated by liposomes modified with a pH-sensitive poly(ethylene glycol) derivative, BEA, 1325, 143-154 (1997). (15) M.A. Elorza, B. Elorza, and J. R. Chantreset, Stability of liposomal formulations: Action of amphi- philic molecules, Int. J. Pharmaceut., 158, 173-183 (1997).
J. Cosmet. Sci. 1 59, 151-156 (March/April 2008) Comparison of hair shaft damage after UVA and UVB irradiation SOO-YOUNG JEON, LONG QUAN PI, and WON-SOO LEE, Department of Dermatology and Institute of Hair and Cosmetic Medicine, Yonsei University Wonju College of Medicine, Ilsan-dong 162, Wonju, Korea. Accepted for publication October 12, 2007. Synopsis Sunlight, especially ultraviolet (UV) light-induced hair damage is difficult to avoid during daily life. Concerns about the effects of ultraviolet light on hair are emerging recently. These photochemical changes mainly come from damage to hair proteins and melanins. In this study, we performed experiments to find the patterns of morphological and biochemical changes in UV-light-induced damage to hair by scanning and transmission electron microscopy and hair protein analysis. In our results, morphological damage is significant in DVB-irradiated hairs, while biochemical changes are greater in UVA-irradiated hairs. INTRODUCTION Changes in hair fibers induced by UV light are largely composed of physical and chemical changes. As for physical changes, dryness, reduced strength, rough surface texture, loss of color, decreased luster, stiffness, and brittleness may occur. In respect to chemical changes, hair proteins, lipids, and hair pigments can change. When light irradiates the hair shaft, the amino acids in the cuticle are altered more than those in the cortex because the outer layers receive higher intensities of radiation (1). Beyak et al. (2) reported that sunlight and UV light decreased tensile properties of wet human hairs and that degrees of damage are related to the total doses of radiation rather than a specific wavelength. But, in another study, it was reported that the specific wavelength of UV irradiation, especially between 254 and 400 nm, seemed to damage hair more severely than did other wavelengths (3). Hoting et al. (4) showed that the cell membrane complex (CMC) lipids of hair fibers was degraded mainly by visible light but that UV A and UVB light also participated in the damaging process. He explained that weakening of the CMC and multiple fractures in hair occurred by a combination of the effects of visible and UV light. Address all correspondence to Won-Soo Lee. 151
Previous Page Next Page